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	Provedor de dados Genet. Mol. Biol. (2) Electron. J. Biotechnol. (1) Autor Salzano,Francisco Mauro (2) Amorim,Carlos Eduardo G. (1) Bau,Claiton Dotto (1) Bortolini,Maria Cátira (1) Cazarolli,Juciana (1) Cervera,María Teresa (1) Chies,José Artur Bogo (1) Comas,David (1) Gallo,Leonardo A (1) Marchelli,Paula (1) Paixão-Côrtes,Vanessa Rodrigues (1) Pastorino,Mario J (1) Poltri,Susana Marcucci (1) Pomponio,María F (1) Rovaris,Diego (1) Schiengold,Marion (1) Torales,Susana (1) Veit,Tiago Degani (1) Viscardi,Lucas Henriques (1) Mais... Palavra-chave Balancing selection (3) Adaptive variation (1) Amerindians (1) Behavioral genes (1) Evolution (1) HLA-G 14 bp INDEL (1) Human behavior (1) Immune genes (1) Patagonian cypress (1) Pathogen resistance (1) Single nucleotide polymorphisms (SNPs) (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Journal article (1) Ano 2018 (1) 2013 (1) 2012 (1) País Brazil (2) Chile (1) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última DNA sequence variation of drought-response candidate genes in Austrocedrus chilensis Electron. J. Biotechnol. Pomponio,María F; Torales,Susana; Gallo,Leonardo A; Pastorino,Mario J; Marchelli,Paula; Cervera,María Teresa; Poltri,Susana Marcucci. Background: Austrocedrus chilensis (D. Don) Pic. Ser. et Bizzarri commonly known as Patagonian cypress is a member of the Cupressaceae family, characterized by a high adaptive potential for growing in marginal areas and good timber quality. The species grows over a wide area and under a wide range of rainfall. This study assessed adaptive genetic variation at SNP level in candidate genes involved in response to drought stress. Results: A total of 18 single nucleotide polymorphisms (SNPs) were found among 1,428 bp. Average nucleotide diversity value (π = 0.00312) was similar to those previously reported in other Cupressaceae. The Fst average among genes and populations was 0.163 and the lowest differentiation was observed in continuous and humid... Tipo: Journal article Palavras-chave: Adaptive variation; Balancing selection; Patagonian cypress; Single nucleotide polymorphisms (SNPs). Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000200003 New evidence for balancing selection at the HLA-G locus in South Amerindians Genet. Mol. Biol. Veit,Tiago Degani; Cazarolli,Juciana; Salzano,Francisco Mauro; Schiengold,Marion; Chies,José Artur Bogo. HLA-G is a non-classical HLA (Human Leukocyte Antigen) molecule characterized by limited tissue distribution under normal physiological conditions and low variability at both DNA and protein levels. Several studies suggest that HLA-G could play a role, as an immunoregulatory molecule, in situations as diverse as transplantation, cancer, viral infections and inflammatory diseases. A total of 237 individuals from 21 South American tribes speaking nine different linguistic families were studied in relation to the 14 bp insertion/deletion polymorphism at the HLA-G gene. A consistent (seven in nine) excess of heterozygosity in samples classified by language was obtained. Our data supply evidences for balancing selection acting at the HLA-G 14 bp INDEL region.... Tipo: Info:eu-repo/semantics/article Palavras-chave: HLA-G 14 bp INDEL; Balancing selection; Amerindians; Pathogen resistance. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000600005 Searching for ancient balanced polymorphisms shared between Neanderthals and Modern Humans Genet. Mol. Biol. Viscardi,Lucas Henriques; Paixão-Côrtes,Vanessa Rodrigues; Comas,David; Salzano,Francisco Mauro; Rovaris,Diego; Bau,Claiton Dotto; Amorim,Carlos Eduardo G.; Bortolini,Maria Cátira. Abstract Hominin evolution is characterized by adaptive solutions often rooted in behavioral and cognitive changes. If balancing selection had an important and long-lasting impact on the evolution of these traits, it can be hypothesized that genes associated with them should carry an excess of shared polymorphisms (trans- SNPs) across recent Homo species. In this study, we investigate the role of balancing selection in human evolution using available exomes from modern (Homo sapiens) and archaic humans (H. neanderthalensis and Denisovan) for an excess of trans-SNP in two gene sets: one associated with the immune system (IMMS) and another one with behavioral system (BEHS). We identified a significant excess of trans-SNPs in IMMS (N=547), of which six of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Human behavior; Evolution; Balancing selection; Immune genes; Behavioral genes. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000100067 Registros recuperados: 3 Primeira ... 1 ... Última

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