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The surgical viability and radiological monitoring of brain implants of bioactive micro-seeds in an animal model BABT
Silva,Giane X. O.; Campos,Tarcisio Passos Ribeiro de; Siqueira,Sávio Lana; Maciel,Marcelo B..
The interstitial implant is a therapeutic modality in brachytherapy of the head and neck. Presently, the seeds implanted in tumors in the central nervous system are metallic I-125. After the full emission of the radionuclide, the seed remains inert in the implanted area. Bioactive ceramic seeds have been prepared for this research group incorporating Sm-152 to be active in Sm-153. The main goal of the present study is the development of a the surgical technique for implanting the biodegradable radioactive micro-seeds in the brains of rabbits, as well as the observation of the clinical reactions of the animal after implantation of two sets of three seeds. The surgical procedure consisted of performing two separate perforations 10 mm from each other in the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: BrainImplant; Surgery; Bioactive seeds; Sm-153.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700016
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