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New stereoisomeric derivatives of jasmonic acid generated by biotransformation with the fungus Gibberella fujikuroi affect the viability of human cancer cells Electron. J. Biotechnol.
Carvajal,Marcela; Espinoza,Luis; Caggia,Silvia; Cardile,Venera; Garbarino,Juan A; Peña-Cortés,Hugo; Russo,Alessandra.
Background: Several studies have shown that (-)-Jasmonic acid, (+)-7-iso-Jasmonic acid and its methyl ester, methyl jasmonate, have anti-cancer activity in vitro and in vivo, exhibiting selective cytotoxicity towards cancer cells. The degree of activity of these molecules is strongly related to their stereochemistry. The biotransformation of known compounds, natural or synthesized, related to interesting biological activities, generates new molecules displaying new improved properties compared with the original ones, increasing its value and providing new more effective products. Therefore, based on the above rationales and observations, in this work a biotransformation protocol to modify the chemical structure of the plant hormone jasmonic acid by using...
Tipo: Journal article Palavras-chave: Apoptosis; Biotransformations; Cancer cells; Cell vitality; Gibberella fujikuroi; Jasmonic acid.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582011000200007
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Optimisation de deux systèmes de production piscicole : biotransformation des nutriments et gestion des rejets ArchiMer
Roque D'Orbcastel, Emmanuelle.
Sustainability of fish aquaculture is currently subjected to environmental protection enhancement and to increasing restrictions of water and energy availability. The aim of this work was to study the biotransformations and waste management in a salmonid french farm (Charles Murgat S.A.S, Isère). Quantification of the wastes is necessary for the farmers and administrations to define control tools and treatment systems in view of water legislation respect (French water low, EC Water Framework Directive). The nutritional method gives a direct relation between feed and effluent fluxes. This method is easier to use than the hydrobiological method, which requires precise flow rate and concentration measurements (difficult and expensive). Solid waste treatment...
Tipo: Text Palavras-chave: Traitement de l'eau; Rejets; Analyse du cycle de vie; Bien être; Recirculation; Biotransformations; Salmonidés; Pisciculture.
Ano: 2008 URL: http://archimer.ifremer.fr/doc/2008/these-3893.pdf
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Microorganisms as tools in modern chemistry: the biotransformation of 3-indolylacetonitrile and tryptamine by fungi BJM
Boaventura,Maria Amélia D.; Lopes,Rosiane F.A.P.; Takahashi,Jacqueline A..
Chemical reactions performed by microorganisms have been used as a modern tool in chemistry. In this work, the ability of the fungi Beauveria bassiana and Aspergillus niger to modify the chemical structure of indole compounds was studied. Beauveria bassiana was able to transform 3-indolylacetonitrile into 3-methylindole while Aspergillus niger transformed tryptamine into 5-hydroxyindole-3-acetamide. Interestingly, these fungi were able to perform both reduction and oxidation of the indole compounds fed, the oxidation occurring with improved levels of oxygen uptake. The results prove once more the versatility of microorganisms to perform a wide range of industrially attractive chemical reactions.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biotransformations; Beauveria bassiana; Aspergillus niger; 3-indolylacetonitrile; Tryptamine.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822004000300014
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