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Effect of exercise on cardiovascular parameters in search and rescue-trained dogs Arq. Bras. Med. Vet. Zootec.
Santos,P.O.P.R.; Santos,E.A.; Reis,A.C.; Santos,A.M.M.R.; Kuster,M.C.C.; Trivilin,L.O.; Aptekmann,K.P..
ABSTRACT Physical activity alters the cardiovascular system of dogs, depending on the exercise characteristics and the animal’s physical conditioning. Little is known about the cardiovascular changes in rescue-trained dogs. This study evaluated the cardiovascular responses to a search and rescue exercise session to differentiate these alterations from cases of exhaustion or some possible pathology. Nine healthy rescue-trained dogs that trained for at least one year were used. Seven German Shepherds and two Belgian Shepherd Malinois were evaluated twice, immediately before exercise (M0) and immediately after a 20-minute training (M1). Electrocardiographic, echocardiographic, and systemic blood pressure (SBP) measurements were performed at each evaluation....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Working dog; Blood pressure; Echocardiography; Electrocardiography; Exercise physiology.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000401036
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Effects of timolol maleate, levobunolol and apraclonidine on intraocular pressure, pupil size, blood pressure and heart rate in beagles Arq. Bras. Med. Vet. Zootec.
Padua,I.R.M.; Ribeiro,A.P.; Padua,P.P.M.; Guimarães,P.J.; Silva,M.L.; Piso,D.Y.T.; Martins,B.; Aldrovani,M.; Semolin,L.M.S.; Camacho,A.A.; Laus,J.L..
ABSTRACT The aim of this study was to evaluate changes in intraocular pressure (IOP), pupil size (PS), blood pressure (BP), heart rate (HR), and ECG variables (Pms wave PmV, PR interval, QRS complex, RMV wave and QT intervals) over time during the instillation of 0.5% timolol, 0.5% levobunolol and 0.5% apraclonidine in clinically normal dogs. Ten adult beagles were used. Baseline values were measured at 8a.m., 2p.m. and 8p.m., for three consecutive days. A waiting period of 10 days between the administrations of each drug was established. For 15 consecutive days, the drug being tested was instilled in one eye of each dog twice a day (7a.m. and 7p.m.). The parameters were evaluated at the aforementioned times on days 3, 6, 9, 12 and 15. Data were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Timolol maleate; Levobunolol; Apraclonidine; Intraocular pressure; Pupil size; Heart rate; Blood pressure.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000300641
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Malnutrition affects the pressor response to microinjection of L-glutamate into the RVLM of awake rats Biol. Res.
Rodrigues,Fabiana Aparecida; Chianca-Jr,Deoclecio Alves; Gonçalves Fernandes,Luciano.
Post-weaning protein malnutrition is often related to the development of cardiovascular and metabolic diseases in humans, as well to changed content of neurotransmitters in the central nervous system under experimental conditions. The rostral ventrolateral medulla (RVLM) is a bulbar region that contains sympathetic premotor neurons; the excitatory amino acid L-glutamate seems to be the main neurotransmitter at this level. The aim of the present study was to evaluate the possible change in the L-glutamate sensitivity of the RVLM neurons of malnourished animals. Male Fischer rats were divided into two groups: control (n = 15) and malnourished (n = 19). Four days before the experiments, guide cannulas were implanted bilaterally in direction of the RVLM for...
Tipo: Journal article Palavras-chave: Baroreflex; Blood pressure; L-glutamate receptors; Heart rate; Malnutrition; RVLM.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400002
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Chronobiologic blood pressure assessment: Maturation of the daily rhythm in newborn foals Biol. Res.
PICCIONE,GIUSEPPE; ASSENZA,ANNA; FAZIO,FRANCESCO; GIANNETTO,CLAUDIA; CAOLA,GIOVANNI.
Circadian rhythmicity of physiological processes in animals has been described for some variables. In order to investigate the daily rhythmicity of blood pressure, seven foals (Equus caballus) were used for 40 days after birth. Measurements of blood pressure were done by means of an oscillometric apparatus (Argus TM-7, Schiller, Barr Switzerland) with the foals in a standing position and the cuff placed around the tail. Blood pressure was recorded twice a day, 1 hour before dawn and 1 hour before dusk for the first 10 days of life, every 2 days from the 11th to the 32nd day, on the 36th and on the 40th day. Two-way repeated measures analysis of variance (ANOVA) were used to determine statistically significant differences between the mean values recorded at...
Tipo: Journal article Palavras-chave: Blood pressure; Circadian rhythm; Chronophisiology; Foals; Equus caballus.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000100007
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Effects of Emerita brasiliensis flour supplementation on normotensive (Wistar) and spontaneously hypertensive rats (SHR) BABT
Cavargere,Victor Agati; França,Camille Feitoza; Cardoso,Ricardo; Vianna,Lucia Marques.
Several studies characterize the connection of overweight and obesity with chronic diseases. Therefore, new alternatives are being studied for controlling hypertension, such as chitin and chitosan fibers, commonly found on crustacean's carapace like Emerita brasiliensis. Rats from two different strains were divided into control and supplemented groups (n=6). The Wistar strain experiment started with a 14-days baseline period, followed by supplementation of E.brasiliensis flour added to the diet in the doses of 5, 10 and 20%, for a 14-days period each. With the optimal dose of 20%, the study was undertaken with SHR rats, starting with a 7-days baseline period, followed by three weeks of supplementation. Data were evaluated using one-way ANOVA and p<0.05...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chitin; Chitosan; Emerita brasiliensis; Blood pressure.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000400006
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Biological response of spontaneously hypertensive rats to the streptozotocin administration BABT
Costa,Virginia Alice Vieira da; Vianna,Lucia Marques.
The sensitivity of adult spontaneously hypertensive rats (SHR) to the diabetogenic effect of streptozotocin (STZ) was studied. The animals were subdivided into three groups: control (citrate buffer), streptozotocin 40 mg/kg or 50 mg/kg, and general biologic parameters were analyzed, in addition to systolic blood pressure, blood glucose and insulin levels determinations. Both doses were able to induce hyperglycemia above 300 mg/dl; however, 50 mg/kg provoked a more pronounced physiological alterations in body weight, diuresis, water and food intake. There was no change on systolic blood pressure with either dose. Results suggested that SHRs did not need doses of streptozotocin above 40mg/kg in order to produce diabetes probably because this strain was much...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptozotocin; SHR; Diabetes; Blood pressure; Insulin.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000100006
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Cardiovascular and respiratory responses to microinjection of L-glutamate into the caudal pressor area in conscious and anesthetized rats BJMBR
Silva,N.F.; Pires,J.G.P.; Campos,R.R.; Futuro Neto,H.A..
The role of the caudal pressor area (CPA) in the maintenance of vasomotor tonus in anesthetized and decerebrate animals has been clearly established. In conscious animals, however, the participation of CPA in the cardiovascular control remains to be fully elucidated. In the present study, unilateral L-glutamate (L-Glu) (10 and/or 20 nmol/70 nl) microinjection into CPA, in conscious male Wistar rats (250-280 g) caused a significant increase in mean arterial blood pressure (MAP; control: 112 ± 1.9 mmHg; after 20 nmol L-Glu: 139 ± 4.5 mmHg, N = 12, P<0.05) and respiratory rate (control: 81 ± 3.5 breaths/min; after 10 nmol L-Glu: 92 ± 3 breaths/min, P<0.05; after 20 nmol L-Glu: 104 ± 5 breaths/min, N = 6, P<0.05). The subsequent anesthesia with...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Caudal pressor area; Ventrolateral medulla; Blood pressure; L-glutamate; Respiration.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001200013
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Hemodynamic mechanisms of the attenuated blood pressure response to mental stress after a single bout of maximal dynamic exercise in healthy subjects BJMBR
Neves,F.J.; Carvalho,A.C.G.; Rocha,N.G.; Silva,B.M.; Sales,A.R.K.; Castro,R.R.T. de; Rocha,J.D.; Thomaz,T.G.; Nóbrega,A.C.L..
To determine the hemodynamic mechanisms responsible for the attenuated blood pressure response to mental stress after exercise, 26 healthy sedentary individuals (age 29 ± 8 years) underwent the Stroop color-word test before and 60 min after a bout of maximal dynamic exercise on a treadmill. A subgroup (N = 11) underwent a time-control experiment without exercise. Blood pressure was continuously and noninvasively recorded by infrared finger photoplethysmography. Stroke volume was derived from pressure signals, and cardiac output and peripheral vascular resistance were calculated. Perceived mental stress scores were comparable between mental stress tests both in the exercise (P = 0.96) and control (P = 0.24) experiments. After exercise, the blood pressure...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cardiovascular system; Blood pressure; Exercise test; Stroop test.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000700007
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Involvement of catecholaminergic medullary pathways in cardiovascular responses to acute changes in circulating volume BJMBR
Cravo,S.L.; Lopes,O.U; Pedrino,G.R.
Water deprivation and hypernatremia are major challenges for water and sodium homeostasis. Cellular integrity requires maintenance of water and sodium concentration within narrow limits. This regulation is obtained through engagement of multiple mechanisms and neural pathways that regulate the volume and composition of the extracellular fluid. The purpose of this short review is to summarize the literature on central neural mechanisms underlying cardiovascular, hormonal and autonomic responses to circulating volume changes, and some of the findings obtained in the last 12 years by our laboratory. We review data on neural pathways that start with afferents in the carotid body that project to medullary relays in the nucleus tractus solitarii and caudal...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Baroreceptors; A1 noradrenergic neurons; AV3V; Renal vascular conductance; Blood pressure; Hypertonic saline.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000900008
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Relationship between salt consumption measured by 24-h urine collection and blood pressure in the adult population of Vitória (Brazil) BJMBR
Rodrigues,S.L.; Souza Júnior,P.R.; Pimentel,E.B.; Baldo,M.P.; Malta,D.C.; Mill,J.G.; Szwarcwald,C.L..
High salt intake is related to an increase in blood pressure and development of hypertension. However, currently, there are no national representative data in Brazil using the gold standard method of 24-h urine collection to measure sodium consumption. This study aimed to determine salt intake based on 24-h urine collection in a sample of 272 adults of both genders and to correlate it with blood pressure levels. We used a rigorous protocol to assure an empty bladder prior to initiating urine collection. We excluded subjects with a urine volume <500 mL, collection period outside of an interval of 23-25 h, and subjects with creatinine excretion that was not within the range of 14.4-33.6 mg/kg (men) and 10.8-25.2 mg/kg (women). The mean salt intake was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sodium; Salt intake; Blood pressure; Hypertension; 24-h urine collection; Population-based study.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000800728
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Dynamic resistance training decreases sympathetic tone in hypertensive ovariectomized rats BJMBR
Shimojo,G.L.; Palma,R.K.; Brito,J.O.; Sanches,I.C.; Irigoyen,M.C.; De Angelis,K..
The aim of this study was to investigate the effects of resistance exercise training on hemodynamics and cardiac autonomic control in ovariectomized spontaneously hypertensive rats. Female rats were divided into 4 groups: sedentary control (SC), sedentary hypertensive (SH), sedentary hypertensive ovariectomized (SHO), and resistance-trained hypertensive ovariectomized (RTHO). Resistance exercise training was performed on a vertical ladder (5 days/week, 8 weeks) at 40-60% maximal load. Direct arterial pressure was recorded. Vagal and sympathetic tones were measured by heart rate (HR) responses to methylatropine (3 mg/kg, iv) and propranolol (4 mg/kg, iv). Ovariectomy resulted in additional increases in blood pressure in hypertensive rats and was associated...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Resistance exercise training; Menopause; Hypertension; Sympathetic tone; Blood pressure.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000600523
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Angiotensin and baroreflex control of the circulation BJMBR
Head,G.A.; Saigusa,T.; Mayorov,D.N..
There is a close association between the location of angiotensin (Ang) receptors and many important brain nuclei involved in the regulation of the cardiovascular system. The present review encompasses the physiological role of Ang II in the brainstem, particularly in relation to its influence on baroreflex control of the heart and kidney. Activation of AT1 receptors in the brainstem by fourth ventricle (4V) administration to conscious rabbits or local administration of Ang II into the rostral ventrolateral medulla (RVLM) of anesthetized rabbits acutely increases renal sympathetic nerve activity (RSNA) and RSNA baroreflex responses. Administration of the Ang antagonist Sarile into the RVLM of anesthetized rabbits blocked the effects of Ang II on the RSNA...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiotensin II; AT1 receptors; Losartan; Renal sympathetic activity; Baroreflex; Rostral ventrolateral medulla; Blood pressure; Rabbit.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000900005
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Central injection of captopril inhibits the blood pressure response to intracerebroventricular choline BJMBR
Isbil-Buyukcoskun,N.; Gulec,G.; Ozluk,K.; Ulus,I.H..
In the present study, we investigated the involvement of the brain renin-angiotensin system in the effects of central cholinergic stimulation on blood pressure in conscious, freely moving normotensive rats. In the first step, we determined the effects of intracerebroventricular (icv) choline (50, 100 and 150 µg) on blood pressure. Choline increased blood pressure in a dose-dependent manner. In order to investigate the effects of brain renin-angiotensin system blockade on blood pressure increase induced by choline (150 µg, icv), an angiotensin-converting enzyme inhibitor, captopril (25 and 50 µg, icv), was administered 3 min before choline. Twenty-five µg captopril did not block the pressor effect of choline, while 50 µg captopril blocked it significantly....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Choline; Captopril; Intracerebroventricular choline; Blood pressure.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600018
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Salt and insulin sensitivity after short and prolonged high salt intake in elderly subjects BJMBR
Lima,N.K.C.; Tozetto,D.J.O.; Lima,L.G.; Nobre,F.; Moriguti,J.C.; Ferriolli,E.; Foss,M.C..
Salt sensitivity and insulin resistance are correlated with higher cardiovascular risk. There is no information about changes in salt sensitivity (SS) and insulin sensitivity (IS) after a chronic salt overload in humans. The aim of this study was to evaluate these parameters in the elderly. Seventeen volunteers aged 70.5 ± 5.9 years followed a low-salt diet (LSD) for 1 week and a high-salt diet (HSD) for 13 weeks. We evaluated SS after one week (HSD1) and after 13 weeks (HSD13), and subjects’ IS and lipids on their usual diet (UD) at HSD1, and at HSD13. Blood pressure (BP) was measured at each visit and ambulatory blood pressure monitoring (ABPM) was performed twice. SS was the same at HSD1 and HSD13. Systolic BP was lower on LSD than on UD (P = 0.01),...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Salt sensitivity; Insulin sensitivity; Elderly; Ambulatory blood pressure monitoring; Blood pressure.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800008
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Baroreflex function in conscious rats submitted to iron overload BJMBR
Cardoso,L.M.; Pedrosa,M.L.; Silva,M.E.; Moraes,M.F.D.; Colombari,E.; Chianca-Jr.,D.A..
Our hypothesis is that iron accumulated in tissue, rather than in serum, may compromise cardiovascular control. Male Fischer 344 rats weighing 180 to 220 g were divided into 2 groups. In the serum iron overload group (SIO, N = 12), 20 mg elemental iron was injected ip daily for 7 days. In the tissue iron overload group (TIO, N = 19), a smaller amount of elemental iron was injected (10 mg, daily) for 5 days followed by a resting period of 7 days. Reflex heart rate responses were elicited by iv injections of either phenylephrine (0.5 to 5.0 µg/kg) or sodium nitroprusside (1.0 to 10.0 µg/kg). Baroreflex curves were determined and fitted to sigmoidal equations and the baroreflex gain coefficient was evaluated. To evaluate the role of other than a direct effect...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Baroreflex; Iron overload; Heart rate; Blood pressure; Iron dextran; Deferoxamine.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000200008
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The physiological role of AT1 receptors in the ventrolateral medulla BJMBR
Tagawa,T.; Fontes,M.A.P.; Potts,P.D.; Allen,A.M.; Dampney,R.A.L..
Neurons in the rostral and caudal parts of the ventrolateral medulla (VLM) play a pivotal role in the regulation of sympathetic vasomotor activity and blood pressure. Studies in several species, including humans, have shown that these regions contain a high density of AT1 receptors specifically associated with neurons that regulate the sympathetic vasomotor outflow, or the secretion of vasopressin from the hypothalamus. It is well established that specific activation of AT1 receptors by application of exogenous angiotensin II in the rostral and caudal VLM excites sympathoexcitatory and sympathoinhibitory neurons, respectively, but the physiological role of these receptors in the normal synaptic regulation of VLM neurons is not known. In this paper we...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiotensin receptors; Central cardiovascular pathways; Blood pressure; Hypothalamus; Neurotransmitters.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000600005
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Functional mapping of the cardiorespiratory effects of dorsal and median raphe nuclei in the rat BJMBR
Alvarenga,R.M.; Pires,J.G.P.; Futuro Neto,H.A..
The dorsal (DRN) and median (MRN) raphe nuclei are important sources of serotonergic innervation to the forebrain, projecting to sites involved in cardiovascular regulation. These nuclei have been mapped using electrical stimulation, which has the limitation of stimulating fibers of passage. The present study maps these areas with chemical stimulation, investigating their influence on cardiorespiratory parameters. Urethane-anesthetized (1.2 g/kg, iv) male Wistar rats (280-300 g) were instrumented for pulsatile and mean blood pressure (MBP), heart rate, renal nerve activity, and respiratory frequency recordings. Microinjections of L-glutamate (0.18 M, 50-100 nl with 1% Pontamine Sky Blue) were performed within the DRN or the MRN with glass micropipettes. At...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dorsal raphe nucleus; Median raphe nucleus; L-glutamate; Blood pressure; Respiration; Sympathetic nerve activity.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001100022
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Effects of metformin on the glycemic control, lipid profile, and arterial blood pressure of type 2 diabetic patients with metabolic syndrome already on insulin BJMBR
Mourão-Júnior,C.A.; Sá,J.R.; Guedes,O.M.S.; Dib,S.A..
Fifty-seven type 2 diabetic patients with metabolic syndrome and on insulin were assessed by a paired analysis before and 6 months after addition of metformin as combination therapy to evaluate the impact of the association on glycemic control, blood pressure, and lipid profile. This was a historical cohort study in which the files of type 2 diabetic patients with metabolic syndrome on insulin were reviewed. The body mass index (BMI), waist circumference, lipid profile, A1C level, fasting blood glucose level, daily dose of NPH insulin, systolic blood pressure, and diastolic blood pressure were assessed in each patient before the start of metformin and 6 months after the initiation of combination therapy. Glycemic control significantly improved (P <...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Type 2 diabetes mellitus; Metabolic syndrome; Metformin; Blood pressure; Cholesterol; Triglycerides.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400009
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Oral administration of L-arginine decreases blood pressure and increases renal excretion of sodium and water in renovascular hypertensive rats BJMBR
Gouvêa,S.A.; Moysés,M.R.; Bissoli,N.S.; Pires,J.G.P.; Cabral,A.M.; Abreu,G.R..
The two-kidney, one-clip renovascular (2K1C) hypertension model is characterized by a reduction in renal flow on the clipped artery that activates the renin-angiotensin system. Endothelium dysfunction, including diminished nitric oxide production, is also believed to play a role in the pathophysiology of this model. Some studies have shown an effect of L-arginine (L-Arg, a nitric oxide precursor) on hypertension. In the present study we determined the ability of L-Arg (7 days of treatment) to reduce blood pressure and alter renal excretions of water, Na+ and K+ in a model of 2K1C-induced hypertension. Under ether anesthesia, male Wistar rats (150-170 g) had a silver clip (0.20 mm) placed around the left renal artery to produce the 2K1C renovascular...
Tipo: Info:eu-repo/semantics/article Palavras-chave: L-arginine; Nitric oxide; Renovascular hypertension; Sodium excretion; Renal physiology; Blood pressure.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000700017
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Evaluation of cardiovascular toxicity of carbon nanotubes functionalized with sodium hyaluronate in oral regenerative medicine BJMBR
Joviano-Santos,J.V.; Sá,M.A.; De Maria,M.L.A.; Almeida,T.C.S.; Geraldo,V.; Oliveira,S.; Ladeira,L.O.; Ferreira,A.J..
It has been demonstrated that carbon nanotubes (CNTs) associated with sodium hyaluronate (HY-CNTs) accelerate bone repair in the tooth sockets of rats. Before clinical application of HY-CNTs, it is important to assess their biocompatibility. Moreover, cardiac toxicity may be caused by the translocation of these particles to the blood stream. The aim of this study was to evaluate possible changes in cardiovascular function in male Wistar rats whose tooth sockets were treated with either CNTs or HY-CNTs (100 μg/mL, 0.1 mL). Blood pressure and heart rate were monitored in conscious rats 7 days after treatment. Cardiac function was evaluated using the Langendorff perfusion technique. The data showed no changes in blood pressure or heart rate in rats treated...
Palavras-chave: Cardiac function; Blood pressure; Carbon nanotubes; Nanotechnology; Bone repair; Tooth sockets.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000700560
Registros recuperados: 53
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