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| Registros recuperados: 16 | |
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| FINISIE,MELLATIE R.; JOSUÉ,ATCHE; FÁVERE,VALFREDO T.; LARANJEIRA,MAURO C. M.. |
| Bioceramic composites were obtained from chitosan and hydroxyapatite pastes synthesized at physiological temperature according to two different syntheses approaches. Usual analytical techniques (X-ray diffraction analysis, Fourier transformed infrared spectroscopy, Thermo gravimetric analysis, Scanning electron microscopy, X-ray dispersive energy analysis and Porosimetry) were employed to characterize the resulting material. The aim of this investigation was to study the bioceramic properties of the pastes with non-decaying behavior from chitosan-hydroxyapatite composites. Chitosan, which also forms a water-insoluble gel in the presence of calcium ions, and has been reported to have pharmacologically beneficial effects on osteoconductivity, was added to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bioceramic; Chitosan; Hydroxyapatite; Composites; Bone regeneration. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000400006 |
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| Valente,F.L.; Reis,E.C.C.; Sepúlveda,R.V.; Ochoa,C.C.R.; Santos,L.C.; Corsini,C.M.; Borges,A.P.B.. |
| O presente trabalho teve como objetivo avaliar a biocompatibilidade e a osseointegração de compósitos de hidroxiapatita (HA), policaprolactona (PCL) e alendronato (ALN) em defeitos ósseos produzidos no olécrano de coelhos. Trinta e seis coelhos foram distribuídos em quatro grupos, recebendo como tratamento: (1) compósito de HA (49,5%), PCL (49,5%) e ALN (1%); (2) HA (50%) e PCL (50%); (3) PCL (100%); e (4) solução salina 0,9%. As amostras para análise histológica foram coletadas de três animais de cada grupo aos oito, 45 e 90 dias de pós-operatório. No oitavo dia, as bordas do defeito ainda eram identificáveis em todos os grupos. Tecido ósseo novo era formado em contato com o biomaterial apenas nas formulações que incluíam HA. Essas características... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Bone regeneration; Biocompatibility; Biomaterial. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000200543 |
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| Buchaim,R.L.; Andreo,J.C.; Rodrigues,A. C.; Buchaim,D.V.; Dias,D.V.; Daré,L.R.; Roque,D.D.; Roque,J.S.. |
| The objective of this study was to evaluate whether demineralized bovine bone (Gen-ox®) alters bone neoformation in rats submitted to alcoholism. Forty male rats were separated into two groups of 20 rats and distributed as follows: Group E1, which received 25% ethanol and a surgical cavity filled only by a blood clot, and Group E2, which received 25% ethanol and a surgical cavity filled with Gen-ox®. The animals were euthanized at 10, 20, 40 and 60 days after surgery and necropsy was performed. The histomorphological and histometric analyses of the area of connective tissue and bone neoformation showed that the reorganization of the bone marrow and full repair of the surgical cavity in Group E1 occurred more quickly than in Group E2. It was also noted that... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rat; Bone regeneration; Alcoholism. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000300016 |
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| Gomes,C.; Paz,A.H.; Bonilla,A.T.; Corrêa,A.; Cavalcante,R.L.; Veiga,D.; Colomé,L.M.; Foerstnow,L.P.; Contesini,E.A.; Cirne-Lima,E.O.. |
| The objective of this study was to investigate the bone regeneration of a "gold standard" (autograft) from iliac crest associated with cellular therapy in rabbits. A bone defect was created with 10x5x5mm in 28 rabbit mandibles. The control group animals (n=14) were repaired with autograft of iliac crest and the experimental group animals (n=14) received iliac crest autograft in association with mononuclear cells from the bone marrow of the femur. Weekly radiographs were taken of the surgery region and histological analyses was performed in seven animals in each group at 15 days and in seven animals of each group at 30 days after the surgery. A gradual increase of bone density was observed and the experimental animals presented the bone bridge in 85.7%... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabbit; Mandibular reconstruction; Bone regeneration; Graft. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000400007 |
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| Shao,Jin; Zhang,Weiwei; Yang,Tieyi. |
| Bone is a unique tissue which could regenerate completely after injury rather than heal itself with a scar. Compared with other tissues the difference is that, during bone repairing and regeneration, after the inflammatory phase the mesenchymal stem cells (MSCs) are recruited to the injury site and differentiate into either chondroblasts or osteoblasts precursors, leading to bone repairing and regeneration. Besides these two precursors, the MSCs can also differentiate into adipocyte precursors, skeletal muscle precursors and some other mesodermal cells. With this multiline-age potentiality, the MSCs are probably used to cure bone injury and other woundings in the near future. Here we will introduce the recent developments in understanding the mechanism of... |
| Tipo: Journal article |
Palavras-chave: Mesenchymal stem cells; Bone regeneration; Bone repairing; Tissue engineering. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100062 |
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| Mendi,Ayseqül; Yağcı,Beyza Gökçınar; Kızıloğlu,Mustafa; Saraç,Nurdan; Uğur,Aysel; Yılmaz,Derviş; Uçkan,Duygu. |
| ABSTRACT A natural agent that maintains mesenchymal stem cell (MSCs) viability, promotes osteogenic differentiation while modulating the immunological response could achieve success in regeneration during healing and may also prevent bone resorption and improve regeneration. We aimed to demonstrate that a Thymbra spicata var. intricata extract could induce proliferation, differentiation, and modulate the immune responses of mesenchymal stem cells (MSCs). Using xCELLigence, a real-time monitoring system, we obtained a growth curve of MSCs. A dose of 10 µg/mL was the most efficient concentration for vitality. Osteogenic differentiation and antiinflammatory activities were determined by using an ELISA Kit to detect early and late markers of differentiation.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mesenchymal stem cell; Osteogenic differentiation; T. spicata var. intricata; Bone regeneration. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100310 |
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| Alves,Endrigo Gabellini Leonel; Serakides,Rogéria; Rosado,Isabel Rodrigues; Paez,Omar Leonardo Aristizabal; Varon,Jéssica Alejandra Castro; Machado,Felipe Nemer; Fukushima,Fabíola Bono; Góes,Alfredo Miranda; Rezende,Cleuza Maria de Faria. |
| ABSTRACT: The aim of this study was to evaluate the effect of osteoprogenitor cells derived from mesenchymal stem cells from adipose tissue (OC-AD-MSCs), and differentiated into osteoblasts, in the treatment of critical bone defects in dogs. Adipose tissue derived mesenchymal stem cells (AD-MSCs) were subjected to osteogenic differentiation for 21 days and used in the treatment of bone defects in dogs radius. Either three experimental groups were bone defects treated with OC-AD-MSCs (OC), defects filled with autogenous bone (Control- C +), or empty defects (Control- C -). Bone regeneration was assessed by radiology, densitometry, and histomorphometry. The area of new bone formation was higher in the OC group compared to the control group (C-) on... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bone regeneration; Orthopedics; Cellular therapy; Fracture non-union. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000700604 |
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| Muñoz-Ruíz,Abraham; Silva-Benítez,Erika; Soto-Sainz,Eduardo; Cerda-Cristerna,Bernardino; Ortiz-Magdaleno,Mariné; Pozos-Guillen,Amaury; Flores,Héctor. |
| The aim of this study was to evaluate histologically the effect of two biomaterials, a biomaterial derived from porcine Urinary submucosa Bladder Matrix (UBM) and beta-TriCalcium Phosphate (ß-TCP), on bone defects. Twenty male New Zealand rabbits were used; the models were divided in two groups: the UBM group; the ß-TCP group, and a Negative Control (NC) group. Five-mm defects were created in the femur of each model and then the different biomaterials were set in place depending on each group. At 4 and 8 weeks, the animals in the models were sacrificed and samples of the defect site were collected to perform a Hematoxylin and Eosin stain (H&E). Histologically, ß-TCP group at 4 and 8 weeks presented neoformation of bone-like and cartilage-like tissue,... |
| Tipo: Journal article |
Palavras-chave: Urinary bladder matrix; Bone regeneration; Biomaterial; SS-tricalcium phosphate. |
| Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300003 |
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| Silva,C; Olate,S; Pozzer,L; Muñoz,M; Cantín,M; Uribe,F; de Albergaría-Barbosa,J. R. |
| Electrical stimulation has been used in different conditions for tissue regeneration. The aim of this study was to analyze the tissue response of defects created in rabbit skulls to electrical stimulation. Two groups were formed, each with 9 New Zealand rabbits; two 5 mm defects were made, one in each parietal, with one being randomly filled with autogenous bone extracted as particles and the other maintained only with blood clotting. The rabbits were euthanized at 8 weeks and 15 weeks to then study the samples collected histologically. In the 8-week analysis bone formation was observed in the defects in the test and control filled with bone graft, whereas the defects with clotting presented a very early stage of bone formation with abundant connective... |
| Tipo: Journal article |
Palavras-chave: Electrical stimulus; Bone regeneration; Bone graft. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000300054 |
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| Beltrán,Victor; Matthijs,Andries; Borie,Eduardo; Fuentes,Ramón; Valdivia-Gandur,Iván; Engelke,Wilfried. |
| The centripetal resorption of maxilla is a continuous process after tooth loss. For treatment of deficient bone sites, autologous bone grafts may be used, as an alternative, biomaterials can be applied which do not require intra- or extraoral donor sites. The present report we describe the use of anorganic bovine bone (ABB) based on three case reports under different modes: Membrane, rigid barrier and connective tissue graft. Clinical results show that under all conditions, sufficient hard tissue was formed to allow implant born rehabilitation in the former insufficient bone sites. Histologic evaluation revealed trabecular bone in an almost mature matrix with resting particles of ABB. Depending on the original site situation, two step rigid occlusive... |
| Tipo: Journal article |
Palavras-chave: Bone regeneration; Maxilla; Dental implant; Bone defect; Biomaterials. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100011 |
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| Beltrán,Víctor; Engelke,Wilfried; Fuentes,Ramón; Decco,Oscar; Prieto,Ruth; Wilckens,Mario; Borie,Eduardo. |
| The centripetal resorption of maxilla is a continuous process after tooth loss. For treatment of deficient bone sites, autologous bone grafts may be used, as an alternative, biomaterials can be applied which do not require intra or extraoral donor sites. The present report describes the use of occlusive barriers and cortical particulate allograft in transverse maxillary defects. This surgical approach was performed in five patients (4 females and 1 male, aged 20 to 37 years). Clinical results show that sufficient hard tissue was formed to allow implant born rehabilitation in the former insufficient bone sites. Histological evaluation revealed small amounts of newly formed bone with a predominance of collagen fibrous tissue and mature bone with very little... |
| Tipo: Journal article |
Palavras-chave: Bone regeneration; Maxilla; Dental implant; Bone defect; Biomaterials. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000100057 |
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| Cassaro,Claudia Vilalva; Justulin Jr.,Luis Antonio; Lima,Patrícia Rodrigues de; Golim,Marjorie de Assis; Biscola,Natália Perussi; Castro,Mateus Vidigal de; Oliveira,Alexandre Leite Rodrigues de; Doiche,Danuta Pulz; Pereira,Elenize Jamas; Ferreira Jr.,Rui Seabra; Barraviera,Benedito. |
| ABSTRACT Background: Bone tissue repair remains a challenge in tissue engineering. Currently, new materials are being applied and often integrated with live cells and biological scaffolds. The fibrin biopolymer (FBP) proposed in this study has hemostatic, sealant, adhesive, scaffolding and drug-delivery properties. The regenerative potential of an association of FBP, biphasic calcium phosphate (BCP) and mesenchymal stem cells (MSCs) was evaluated in defects of rat femurs. Methods: Adult male Wistar rats were submitted to a 5-mm defect in the femur. This was filled with the following materials and/or associations: BPC; FBP and BCP; FBP and MSCs; and BCP, FBP and MSCs. Bone defect without filling was defined as the control group. Thirty and sixty days... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bone regeneration; Biomaterials; Fibrin sealant; Fibrin biopolymer; Biphasic calcium phosphate; Mesenchymal stem cells. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100320 |
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| Registros recuperados: 16 | |
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