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The presence of pharmacological substances myoglobin and histamine in venoms J. Venom. Anim. Toxins
LIPPS,B. V.; KHAN,A. A..
It is well documented that several pharmacological substances are released within the victim's body after snakebite. These substances are also believed to be endogenously present in animals, specifically levels of myoglobin and histamine that are reported to rise after envenomation. However, there is no published data regarding the presence of these substances in venoms per se. This research reports the detection of myoglobin and histamine in snake, scorpion, honeybee, and toad venoms by immunological test. It is unlikely that the rise in levels of myoglobin and histamine is due to that added from the bite, since a single toxin devoid of such components is capable of elevating levels of these substances. Nonetheless, it is likely that the rise in levels of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Myoglobin; Histamine; Snake; Honeybee; Scorpion; Toad; Venom; Crotalus atrox; Crotalus polystictus; Naja kaouthia; Oxyuranus s. scutellatus; Actinopyga agassizi; Bufo arenarum; Androcetonus australis; Apis mellifera.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302001000100004
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Determinación de la frecuencia de micronúcleos en eritrocitos de Bufo arenarum que habitan ambientes urbanizados Acta Toxicol. Argent.
Caraffa,Evangelina; Bionda,Clarisa del L; Pollo,Favio E; Salas,Nancy E; Martino,Adolfo L.
Los anfibios son constituyentes integrales de ecosistemas naturales y agrícolas, y debido a su sensibilidad pueden ser utilizados como bioindicadores. La frecuencia de micronúcleos se emplea como un biomarcador que evalúa la respuesta a agentes genotóxicos. El objetivo del trabajo fue determinar y comparar la frecuencia de micronúcleos en eritrocitos de Bufo arenarum que habitan ambientes antrópicos de la ciudad de Río Cuarto. Se escogieron tres sitios modificados: un lago urbano Lago Villa Dálcar (33º06´S-64º22´W) y dos sitios de cultivo denominados Cultivo1 (33º05'S-64º26'W) y Cultivo 2 (33º05'S-64º25'W). Como control se escogió un área ubicada en las sierras de Comechingones, en el Campo Experimental Las Guindas (32º35'S- 64º42'W), pertenecientes a la...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Micronúcleos; Anfibios; Bufo arenarum; Agroecosistemas.
Ano: 2013 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432013000200002
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Humoral immune alterations caused by lead: studies on an adult toad model Acta Toxicol. Argent.
Rosenberg,Carolina E.; Fink,Nilda E.; Salibián,Alfredo.
There is evidence that environmental metal levels affect the immune function. In the particular case of the impact of heavy metals, information available suggests that the immune system is a target for low-dose Pb exposure. Among vertebrates it was shown that amphibians are capable of forming antibodies against a variety of antigens, causing several responses such as anaphylactic response and rejecting grafts. In this study, the production of antibodies was assessed against sheep red blood cells (SRBC) in the anuran Bufo arenarum after six weekly injections of sublethal doses of lead (50 mg.kg-1, as lead acetate). Natural antibodies (natural heteroagglutinins) were also quantified against SRBC. Both assessments were carried out employing an ELISA method...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sheep red blood cells (SRBC) antibodies; Heavy metals immunotoxicology; Sublethal lead; Bufo arenarum.
Ano: 2007 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432007000100003
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