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	Provedor de dados BJMBR (2) BJB (1) Autor CARLINI,C. R. (1) Carlini,C.R. (1) FERNANDES,K. V. S. (1) Francisco-DoPrado,J. (1) GOMES,V. M. (1) Melo-Lima,M.H. (1) OLIVEIRA,A. E. A. (1) Olivera-Severo,D. (1) Ribeiro-DaSilva,G. (1) SALES,M. P. (1) Wassermann,G.E. (1) XAVIER-FILHO,J. (1) Zambelli,J.E. (1) Mais... Palavra-chave Canatoxin (3) Blood glucose alterations (1) Canavalia ensiformis (1) Concanavalin A (1) Eicosanoids (1) Endogenous opioids (1) Helicobacter pylori (1) Hyperinsulinemia (1) Inflammation (1) Jack bean seeds (1) Neutrophils (1) Phytopathogenic fungi (1) Sex hormones (1) Urease (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2006 (1) 1999 (1) 1998 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última The toxicity of jack bean [Canavalia ensiformis (L.) DC.] canatoxin to plant pathogenic fungi BJB OLIVEIRA,A. E. A.; GOMES,V. M.; SALES,M. P.; FERNANDES,K. V. S.; CARLINI,C. R.; XAVIER-FILHO,J.. Protein fractions obtained from seeds of the jack bean (Canavalia ensiformis) as well as the amino acid canavanine, present in these seeds, were tested for their capacity to inhibit the growth of the phytopathogenic fungi Macrophomina phaseolina, Colletotrichum gloesporioides, Sclerotium rolfsii and Fusarium oxysporum. We found that most of the proteins examined and also canavanine did not have any effect on the growth of these fungi. On the other hand the toxic protein canatoxin was found to be effective, at a concentration of 2%, in the inhibition of the growth of M. phaseolina, C. gloesporioides and S. rolfsii. Tipo: Info:eu-repo/semantics/article Palavras-chave: Canavalia ensiformis; Jack bean seeds; Canatoxin; Phytopathogenic fungi. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71081999000100008 The hyperinsulinemia produced by concanavalin A in rats is opioid-dependent and hormonally regulated BJMBR Francisco-DoPrado,J.; Zambelli,J.E.; Melo-Lima,M.H.; Ribeiro-DaSilva,G.. The present study examines the effect of concanavalin A (Con A) on the blood insulin and glucose levels of rats. Male and female rats treated with Con A (62.5-500 µg/kg) for three days showed a dose- and time-dependent hyperinsulinemia that lasted more than 48 h. Male rats were more sensitive to Con A. Thus, 6 h after treatment with Con A the circulating insulin levels in male rats had increased by 85% (control: 10.2 ± 0.9 mU/l and Con A-treated: 18.8 ± 1 mU/l) compared to only 38% (control: 7.5 ± 0.2 mU/l; Con A-treated: 10.3 ± 0.9 mU/l) in females. An identical response was seen after 12 h. Con A (250 µg/kg) produced time-dependent hypoglycemia in both sexes but more pronounced in males. There was no correlation between the hypoglycemia and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Concanavalin A; Hyperinsulinemia; Blood glucose alterations; Sex hormones; Endogenous opioids; Canatoxin. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000500015 Ureases display biological effects independent of enzymatic activity: Is there a connection to diseases caused by urease-producing bacteria? BJMBR Olivera-Severo,D.; Wassermann,G.E.; Carlini,C.R.. Ureases are enzymes from plants, fungi and bacteria that catalyze the hydrolysis of urea to form ammonia and carbon dioxide. While fungal and plant ureases are homo-oligomers of 90-kDa subunits, bacterial ureases are multimers of two or three subunit complexes. We showed that some isoforms of jack bean urease, canatoxin and the classical urease, bind to glycoconjugates and induce platelet aggregation. Canatoxin also promotes release of histamine from mast cells, insulin from pancreatic cells and neurotransmitters from brain synaptosomes. In vivo it induces rat paw edema and neutrophil chemotaxis. These effects are independent of ureolytic activity and require activation of eicosanoid metabolism and calcium channels. Helicobacter pylori, a Gram-negative... Tipo: Info:eu-repo/semantics/article Palavras-chave: Urease; Canatoxin; Helicobacter pylori; Inflammation; Neutrophils; Eicosanoids. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000700002 Registros recuperados: 3 Primeira ... 1 ... Última

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