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	Provedor de dados BJMBR (1) Autor Barreto-Chaves,M.L.M. (1) Heimann,A. (1) Krieger,J.E. (1) Palavra-chave Angiotensin-converting enzyme (1) Cardiac myocytes (1) Dexamethasone (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2000 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Stimulatory effect of dexamethasone on angiotensin-converting enzyme in neonatal rat cardiac myocytes BJMBR Barreto-Chaves,M.L.M.; Heimann,A.; Krieger,J.E.. Angiotensin-converting enzyme (ACE) plays a central role in cardiac remodeling associated with pathological conditions such as myocardial infarction. The existence of different cell types in the heart expressing components of the renin-angiotensin system makes it difficult to evaluate their relative role under physiological and pathological conditions. Since myocytes are the predominant cellular constituent of the heart by mass, in the present study we studied the effects of glucocorticoids on ACE activity using well-defined cultures of neonatal rat cardiac myocytes. Under steady-state conditions, ACE activity was present at very low levels, but after dexamethasone treatment ACE activity increased significantly (100 nmol/l after 24 h) in a time-dependent... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dexamethasone; Cardiac myocytes; Angiotensin-converting enzyme. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000600007 Registros recuperados: 1 Primeira ... 1 ... Última

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