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| Gamboa,Ricardo; Huesca-Gómez,Claudia; López-Pérez,Vanessa; Posadas-Sánchez,Rosalinda; Cardoso-Saldaña,Guillermo; Medina-Urrutia,Aida; Juárez-Rojas,Juan Gabriel; Soto,María Elena; Posadas-Romero,Carlos; Vargas-Alarcón,Gilberto. |
| Abstract We examined the role of UCP gene polymorphisms as susceptibility markers for premature coronary artery disease (pCAD). The UCP2 Ala55Val (C/T rs660339), UCP2 -866G/A (rs659366), and UCP3 -55C/T (rs1800849) polymorphisms were genotyped in 948 patients with pCAD, and 763 controls. The distribution of the UCP2 A55V (C/T rs660339) and UCP3 -55 (rs1800849) was similar in patients and controls. However, under a recessive model, the UCP2 -866 (rs659366) A allele was associated with increased risk of developing pCAD (OR = 1.43, Pc = 0.003). On the other hand, patients with pCAD and UCP2 A55V (rs660339) TT showed high levels of visceral abdominal fat (VAF) (Pc = 0.002), low levels of subcutaneous abdominal fat (SAF) (Pc = 0.001) and high VAT/SAT ratio (Pc... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: UCPs polymorphisms; Premature coronary artery; Cardiovascular risk; Mexican population. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000300371 |
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| Guimarães,Milena Maria Moreira; Greco,Dirceu Bartolomeu; Moreira,Allyson Nogueira; Guimarães,Nathalia Sernizon; Freire,Cláudia Maria Vilas; Rohlfs,Bruna Guimarães; Machado,Lucas José de Campos. |
| ABSTRACT The lipid accumulation product (LAP) index is an emerging cardiovascular risk marker. We aimed to assess the accuracy of this index as a marker of cardiovascular risk in HIV-infected patients. A cross-sectional study of 133 HIV-infected patients on antiretroviral drugs and 20 non-infected controls was conducted at the outpatient clinic of a referral center of infectious and parasitic diseases. Evaluations included LAP index, homeostasis model assessment (HOMA) index, anthropometric measurements, blood pressure, glucose tolerance test, and cholesterol and triglyceride levels. Body mass index (BMI) was similar in both groups; however, waist circumference was greater in the HIV-infected patients. Triglyceride levels were significantly higher (p <... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; Hyperlipidemia; Atherosclerosis; Lipid accumulation product index; Cardiovascular risk; Insulin resistance. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300171 |
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| Arruda Junior,Evanizio Roque de; Lacerda,Heloisa Ramos; Moura,Libia Cristina Rocha Vilela; Albuquerque,Maria de Fatima Pessoa Militão de; Miranda Filho,Democrito de Barros; Diniz,George Tadeu Nunes; Albuquerque,Valeria Maria Gonçalves de; Amaral,Josefina Cláudia Zirpoli; Ximenes,Ricardo Alencar de Arraes; Monteiro,Verônica Soares. |
| INTRODUCTION: Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy. OBJECTIVE: Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy. METHOD: Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension. RESULTS: Of 958 patients, 245 (25.6%) had hypertension (cases), 325 (33.9%) had prehypertension, and 388 (40.5%) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV/AIDS; Hypertension; Antiretroviral therapy; Cardiovascular risk. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014 |
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| Firmino,Paulo Yuri Milen; Vasconcelos,Tainá Osterno; Ferreira,Caroline Carneiro; Moreira,Larissa Mendonça; Romero,Nirla Rodrigues; Dias,Lilian Araújo; Queiroz,Maria Goretti Rodrigues de; Lopes,Marcos Venícios de Oliveira; Fonteles,Marta Maria de França. |
| Cardiovascular complications are relevant due to their frequency and severity on the hypertension scenario. Studies refer Pharmaceutical Care (PC) as capable of decreasing cardiovascular risk rate (%CVR) on hypertensive patients. This study aimed to investigate, through a randomized clinical assay, the influence of PC service on the %CVR of hypertensive patients assisted in a health primary care unit from Fortaleza-Ceará. Two study groups were formed: i. Intervention Group (IG), which received orientation about taking medicines, actions aiming to prevent/solve medicine interactions and adverse effects and non-pharmacological interventions for 9 months and, ii. Control Group (CG), which received traditional assistance of the unit and was monitored during... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pharmaceutical care; Cardiovascular risk; Hypertension. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300617 |
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