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	Provedor de dados BJID (1) BJMBR (1) Autor Barichello,T. (1) Chen,Wei (1) Constantino,L.S. (1) Dal-Pizzol,F. (1) Dong,Fang (1) Lu,Huizhi (1) Machado,R.A. (1) Martins,M.R. (1) Moreira,J.C.F. (1) Quevedo,J. (1) Reinke,A. (1) Valvassori,S.S. (1) Wang,Huabing (1) Xu,Liang (1) Mais... Palavra-chave Cecal ligation and puncture (2) Cognitive impairment (1) Forced swimming test (1) Immune regulation (1) Lung injury (1) Plus-maze test (1) Recognition memory (1) Sepsis (1) Sepsis survivors (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2014 (1) 2007 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Therapeutic effects of compound hypertonic saline on rats with sepsis BJID Dong,Fang; Chen,Wei; Xu,Liang; Wang,Huabing; Lu,Huizhi. Sepsis is one of the major causes of death and is the biggest obstacle preventing improvement of the success rate in curing critical illnesses. Currently, isotonic solutions are used in fluid resuscitation technique. Several studies have shown that hypertonic saline applied in hemorrhagic shock can rapidly increase the plasma osmotic pressure, facilitate the rapid return of interstitial fluid into the blood vessels, and restore the effective circulating blood volume. Here, we established a rat model of sepsis by using the cecal ligation and puncture approach. We found that intravenous injection of hypertonic saline dextran (7.5% NaCl/6% dextran) after cecal ligation and puncture can improve circulatory failure at the onset of sepsis. We found that the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Sepsis; Cecal ligation and puncture; Immune regulation; Lung injury. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500518 Behavioral deficits in sepsis-surviving rats induced by cecal ligation and perforation BJMBR Barichello,T.; Martins,M.R.; Reinke,A.; Constantino,L.S.; Machado,R.A.; Valvassori,S.S.; Moreira,J.C.F.; Quevedo,J.; Dal-Pizzol,F.. Sepsis and its complications are the leading causes of mortality in intensive care units, accounting for 10-50% of deaths. Intensive care unit survivors present long-term cognitive impairment, including alterations in memory, attention, concentration, and/or global loss of cognitive function. In the present study, we investigated behavioral alterations in sepsis-surviving rats. One hundred and ten male Wistar rats (3-4 months, 250-300 g) were submitted to cecal ligation and puncture (CLP), and 44 were submitted to sham operation. Forty-four rats (40%) survived after CLP, and all sham-operated animals survived and were used as control. Twenty animals of each group were used in the object recognition task (10 in short-term memory and 10 in long-term memory),... Tipo: Info:eu-repo/semantics/article Palavras-chave: Sepsis survivors; Recognition memory; Plus-maze test; Forced swimming test; Cecal ligation and puncture; Cognitive impairment. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000600013 Registros recuperados: 2 Primeira ... 1 ... Última

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