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In vitro screening of Amazonian plants for hemolytic activity and inhibition of platelet aggregation in human blood Acta Amazonica
Oliveira,Viviana Maria Araújo de; Carneiro,Ana Lucia Basilio; Cauper,Glaucia Socorro de Barros; Pohlit,Adrian Martin.
In the present study, different aerial parts from twelve Amazonian plant species found in the National Institute for Amazon Research's (INPA's) Adolpho Ducke Forest Reserve (in Manaus, Amazonas, Brazil) were collected. Separate portions of dried, ground plant materials were extracted with water (by infusion), methanol and chloroform (by continuous liquid-solid extraction) and solvents were removed first by rotary evaporation, and finally by freeze-drying which yielded a total of seventy-one freeze-dried extracts for evaluation. These extracts were evaluated initially at concentrations of 500 and 100 µg/mL for in vitro hemolytic activity and in vitro inhibition of platelet aggregation in human blood, respectively. Sixteen extracts (23 % of all extracts...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adolpho Ducke Reserve; Chaunochiton kappleri; Diclinanona calycina; Elaeoluma nuda.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672009000400026
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