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CRUZ-RAMÍREZ,Susana-Gabriela; LÓPEZ-SAIZ,Carmen-María; ROSAS-BURGOS,Ema-Carina; CINCO-MOROYOQUI,Francisco-Javier; VELÁZQUEZ,Carlos; HERNÁNDEZ,Javier; BURGOS-HERNÁNDEZ,Armando. |
Abstract The search for chemopreventive/chemoprotective compounds in marine organism has been extensively reported; however, the presence of these compounds in octopus has been incipiently explored. In this research, the antimutagenic, antiproliferative, and antioxidant potential of three crude extracts (methanolic, acetonic, and hexanic) from Paroctopus limaculatus was investigated. Antimutagenic activity against aflatoxin B1 (AFB1) was evaluated through the Ames test using Salmonella typhimurium tester strains TA98 and 100. Antiproliferative activity was assessed using the standard MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide) assay on M12.C3.F6 murine cell line. Antioxidant activity was assessed using the DPPH... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Octopus; Biological activity; Chemopreventive. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612015000400722 |
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