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Comportamiento productivo y niveles de ácido oleico en la canal de corderos suplementados con Saccharomyces cerevisiae. Colegio de Postgraduados
Gloria Trujillo, Adrián.
Los altos niveles de ácidos grasos saturados en la carne de rumiantes representan un punto crítico en la alimentación humana por su relación con enfermedades cardiovasculares. La levadura Saccharomyces cerevisiae (Sc) es rica en ácido oleico y representa una alternativa para modificar el perfil de ácidos grasos de la carne, al incrementar la proporción de ácidos grasos insaturados. Por lo anterior, se realizó un experimento con corderos en crecimiento (20± 0.9 kg PV), utilizando una dieta a base de concentrado y tres niveles (tratamientos, T) de Sc (0, 3 y 5 g animal-1 d-1, T1, T2 y T3, respectivamente), con el objetivo de determinar el comportamiento animal, caracterizar la fermentación ruminal, los niveles plasmáticos de colesterol y los ácidos grasos...
Palavras-chave: Saccharomyces cerevisiae; Oleico; Corderos; Fermentación ruminal; Colesterol; Oleic; Lambs; Ruminal fermentation; Cholesterol; Ganadería; Maestría.
Ano: 2012 URL: http://hdl.handle.net/10521/773
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Comportamiento productivo y niveles de ácido oleico en la canal de corderos suplementados con Saccharomyces cerevisiae. Colegio de Postgraduados
Gloria Trujillo, Adrián.
Los altos niveles de ácidos grasos saturados en la carne de rumiantes representan un punto crítico en la alimentación humana por su relación con enfermedades cardiovasculares. La levadura Saccharomyces cerevisiae (Sc) es rica en ácido oleico y representa una alternativa para modificar el perfil de ácidos grasos de la carne, al incrementar la proporción de ácidos grasos insaturados. Por lo anterior, se realizó un experimento con corderos en crecimiento (20± 0.9 kg PV), utilizando una dieta a base de concentrado y tres niveles (tratamientos, T) de Sc (0, 3 y 5 g animal-1 d-1, T1, T2 y T3, respectivamente), con el objetivo de determinar el comportamiento animal, caracterizar la fermentación ruminal, los niveles plasmáticos de colesterol y los ácidos grasos...
Palavras-chave: Saccharomyces cerevisiae; Oleico; Corderos; Fermentación ruminal; Colesterol; Oleic; Lambs; Ruminal fermentation; Cholesterol; Ganadería; Maestría.
Ano: 2012 URL: http://hdl.handle.net/10521/773
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Specific nutrient supplementation of defined serum-free medium for the improvement of CHO cells growth and t-PA production Electron. J. Biotechnol.
Altamirano,Claudia; Illanes,Andrés; Canessa,Rossana; Becerra,Silvana.
Recombinant CHO TF70R cells are able to grow and produce t-PA on serum-free medium BIOPRO1 (BioWhitaker Europe, Belgium). The purpose of the present study was to determine the effect of medium supplementation with vitamins, lipids, and specific amino acids on cell growth, t-PA production and biological functionality. Among vitamins, only biotin, folic acid, cobalamine and benzoic acid were required for improving growth and t-PA production. Lipid supplement allowed a significant increase cell concentration and t-PA specific activity and concentration, though its specific production rate decreased slightly. Medium supplementation with proline, serine and asparagine had also positive effects on cell growth. Besides, the addition of asparagine (even in the...
Tipo: Journal article Palavras-chave: Amino acid; Cholesterol; Vitamins.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582006000100009
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CYP3A5 genotyping for assessing the efficacy of treatment with simvastatin and atorvastatin Genet. Mol. Biol.
Kolovou,Genovefa; Kolovou,Vana; Ragia,Georgia; Mihas,Constantinos; Diakoumakou,Olga; Vasiliadis,Ioannis; Mavrogeni,Sophie; Vartela,Vassiliki; Manolopoulos,Vangelis G.
In this work, we examined the impact of polymorphism in the cytochrome P450 (CYP) 3A5 gene, CYP3A5*1 (6986A > G, rs 776746), on the reduction in the lipid levels caused by simvastatin and atorvastatin. We studied 350 hyperlipidemic patients who received 10-40 mg of atorvastatin (n = 175) or simvastatin (n = 175) daily. Genotyping for CYP3A5 was done by PCR-RFLP analysis. Differences in the lipid profile before and after treatment were expressed as the % difference. The frequency of CYP3A5 polymorphism was 13.4% for heterozygotes and 86.6% for homozygotes. Comparison of the responses to same dose of each drug showed that the highest % difference was associated with total cholesterol (TC) in subjects receiving atorvastatin 40 mg compared with simvastatin...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Atorvastatin; Cholesterol; CYP3A5 gene polymorphism; Simvastatin.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000200129
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Mitos e realidades sobre o consumo de carne bovina. Infoteca-e
VALLE, E. R. do.
A carne bovina magra e considerada um alimento de alta densidade nutricional, por apresentar em sua composicao uma grande quantidade de nutrientes, com alta disponibilidade e baixo valor calorico. Ela e rica em proteinas de alta qualidade, acidos graxos essenciais, vitaminas do complexo B (tiamina, riboflavina, niacina, biotina, acido pantotenico, folacina, vitaminas B6 e B12) e minerais como ferro, zinco e fosfora. Todos os nutrientes contidos na carne bovina sao de primordial importancia na alimentacao, destancando-se o ferro. Na carne bovina, o ferro e encontrado na forma heme, de mais facil absorcao pelo organismo humano do que o ferro nao heme, disponivel nos vegetais, cereais, frutas e ovos. No entanto, por ignorancia ou sensacionalismo, informacoes...
Tipo: Documentos (INFOTECA-E) Palavras-chave: Nutrientes; Animal fats.; Bovino; Carne; Colesterol; Gordura; Nutrição Humana.; Cattle; Cholesterol; Human nutrition; Nutrients.; Meat.
Ano: 2000 URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/325130
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Lipid requirements of shrimp ArchiMer
Abramo D', L.
A review of lipid requirements of shrimp and other crustacean species, when applicable, is presented. Qualitative requirements of crustaceans for cholesterol, fatty acids and phospholipids have been documented, but quantitative requirements generally remain undefined. Potential interrelationships between different classes of lipids that may influence requirements as well as differences due to age and species need to be investigated. A more accurate definition of lipid requirements can be achieved by supporting traditional evaluations based upon weight gain and survival with biochemical or histological evidence.
Tipo: Text Palavras-chave: Malacostraca; Biochemical analysis; Nutrients (mineral); Growth; Survival; Cholesterol; Fatty acids; Lipids.
Ano: 1989 URL: http://archimer.ifremer.fr/doc/1989/acte-1470.pdf
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The nutritional requirements of the Japanese shrimp Penaeus japonicus ArchiMer
Guillaume, Julien.
Penaeus japonicus is probably the best known species among penaeids or even among shrimps. In juveniles, the protein requirement was best studied and Japanese shrimp appears as the most demanding penaeid species. They may be related to several factors such as energy level of the diet, digestibility or biological value of protein or other nutritional factors. The essential amino acids are well known, however from a quantitative point of view the requirements in each of these amino acids remain to be determined.
Tipo: Text Palavras-chave: Penaeus japonicus; Malacostraca; Shrimp culture; Glucosamine; Carbohydrates; Feeding; Cholesterol; Fatty acids; Amino acids; Nutritive value; Digestibility; Proteins; Diets; Juveniles.
Ano: 1989 URL: http://archimer.ifremer.fr/doc/1989/acte-1457.pdf
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Effect of fish meal replacement by plant protein sources on non-specific defence mechanisms and oxidative stress in gilthead sea bream (Sparus aurata) ArchiMer
Sitja Bobadilla, A; Pena Llopis, S; Gomez Requeni, P; Medale, Francoise; Kaushik, Sadasivam; Perez Sanchez, J.
Partial or total replacement of fish meal by a mixture of plant protein (PP) sources (corn gluten, wheat gluten, extruded peas, rapeseed meal and sweet white lupin) balanced with indispensable amino acids was examined in juvenile gilthead sea bream over the course of a 6-month growth trial. A diet with fish meal (FM) as the sole protein source was compared to diets with 50%, 75% and 100% of replacement (PP50, PP75, and PP100). The possible influence of diets on growth performance, plasma metabolites, gut integrity, liver structure, anti-oxidant and immune status was evaluated. Final body weight was progressively decreased with PP inclusion, but in PP50 and PP75-fed fish, feed efficiency (FE) was significantly improved and specific growth rates remained...
Tipo: Text Palavras-chave: Gilthead sea bream; Cholesterol; Glutathione; Histopathology; Myeloperoxidase; Complement; Lysozyme; Respiratory burst; Immune response; Growth; Plant proteins; Fish meal.
Ano: 2005 URL: http://archimer.ifremer.fr/doc/2005/publication-3595.pdf
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Hepatoprotective Effects of Tribulus terrestris Hydro-Alcholic Extract on Non-Alcoholic Fatty Liver- Induced Rats International Journal of Morphology
Almasi,Fatemeh; Khazaei,Mozafar; chehrei,Shima; Ghanbari,Ali.
Non-alcoholic fatty liver induces many complications to the liver tissue and also serum related parameters. Medicinal plants are the safe therapeutic strategy for the treatment of diseases. In this regards, the present study was conducted to evaluate the effect of Tribulus terrestris (T. terrestris) extract on non-alcoholic fatty liver in rats. In this experimental study, thirty male Wistar rats were divided into five groups (n=6). Animals in experimental groups were received high fructose diet (70 %) (HDF) daily alone or in combined with daily intraperitoneal injection of 500, 700 and 1000 mg/kg extract of T. terrestris. Control group of rats was feed with standard chow. The serum levels of biomarkers of liver and serum lipid profiles were assessed, also...
Tipo: Journal article Palavras-chave: Cholesterol; NAFLD; Rat; Tribulus Terrestris.
Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000100054
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Somatic, Biochemical and Hepatic Alterations in Wild Type Mice Chronically Fed High Fat Diet International Journal of Morphology
Neves,Renata Heisler; Barros Alencar,Alba Cristina Miranda de; Aguila,Marcia Barbosa; Mandarim-de-Lacerda,Carlos Alberto; Machado-Silva,José Roberto; Gomes,Delir Corrêa.
This study evaluated whether a high fat diet (HFC group) induces overweight, hepatic steatosis and plasma lipoproteins level alteration compared to standard chow diet (SC group). Female mice were submitted to each diet over 6 months. Body mass and food intake were evaluated weekly throughout the experiment. Total cholesterol, TG, LDL-c, HDL-c and VLDL-c were analyzed. Mice were sacrificed to remove liver, spleen, heart and intestine. The volume of the organs was determined according to the submersion method. Fixed livers were embedded in paraffin and stained with hematoxylin and eosin and Masson's trichrome. The analysis used a video microscope system and a test-system with 42 test-points. The volume density was estimated for hepatocytes, steatosis and...
Tipo: Journal article Palavras-chave: Hypercholesterolemia; Experimental model; Mice; Cholesterol; Diet; Liver.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500018
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Effect of Five Single Nucleotide Polymorphisms of ABCG5 and ABCG8 Genes on Ezetimibe Lipid-Lowering Response International Journal of Morphology
Caamaño,José M; Saavedra,Nicolás; Zambrano,Tomás; Lanas,Fernando; Salazar,Luis A.
In this study we evaluated the possible association between five single nucleotide polymorphisms in ABCG5 (rs6720173) and ABCG8 (rs11887534, rs4148211, rs4148217 and rs6544718) genes and ezetimibe response in Chilean hypercholesterolemic subjects. A total of 60 non-related hypercholesterolemic subjects, aged 18 to 65 years old were included in this study. These subjects were treated with ezetimibe (10mg/day) during one month. The ABCG5 and ABCG8 genotypes were assessed by PCR-RFLP. The genotype distribution of the ABCG5/ABCG8 polymorphisms was in Hardy-Weinberg equilibrium. Our results showed that the investigated polymorphisms were not associated with the response to ezetimibe. Nevertheless, the T allele of rs6544718 polymorphism was related to higher...
Tipo: Journal article Palavras-chave: Ezetimibe; Cholesterol; ABCG5/G8; Polymorphisms.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200055
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EFFECTS OF THREE FRACTIONS OBTAINED FROM Naja haje VENOM ON HEMOLYSIS AND LIPID METABOLISM IN RABBITS J. Venom. Anim. Toxins
EL-AAL,A. A.; EZZAT,A. R..
Three fractions (F1, F2 and F3) were obtained from the venom of the Egyptian cobra Naja haje by gel filtration. F1 and F2 had indirect hemolytic effects on rabbit erythrocytes. The HU50 (the amount of the fraction causing 50% hemolysis ) values of F1 and F2 were 12.04 ± 3.89 and 36.57 ± 2.20 µg, respectively. The effects of the three cobra venom fractions on lipid metabolism were studied after 1, 2, 3 and 4 hours. Serum total lipids and cholesterol were significantly decreased at almost all tested times, but variable changes were observed in the serum triglycerides. Serum inorganic phosphorus levels were significantly increased with F1 and F2 administration more than that with the F3 fraction. These results suggest that F1 and F2 possess phospholipase...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Naja haje venom fractions; Hemolysis; Total lipids; Cholesterol; Triglycerides; Inorganic phosphorus.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000200007
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Differences on the Yolk Lipid, Cholesterol and Fatty Acid Composition of Some Commercial Strains OAK
三好, 俊三; 光本, 孝次.
Palavras-chave: 卵黄脂質; コレステロール; 脂肪酸組成; 市販鶏種; Yolk lipid; Cholesterol; Fatty acid composition; Commercial strain.
Ano: 1994 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/446
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Host Cholesterol Synthesis Contributes to Growth of Intracellular Toxoplasma gondii in Macrophages OAK
NISHIKAWA, Yoshifumi; IBRAHIM, Hany M.; KAMEYAMA, Kyohko; SHIGA, Ikumi; HIASA, Jun; XUAN, Xuenan; 西川, 義文; 玄, 学南.
The intracellular protozoan Toxoplasma gondii lacks the ability to synthesize sterol and scavenges cholesterol from the lowdensity lipoprotein receptor (LDLR) pathway of its host to facilitate replication. Sterol biosynthesis inhibitors, however, have a demonstrated anti-Toxoplasma effect. In this study, we examined the host mevalonate pathway as a novel source of cholesterol for T. gondii and its effects on parasite growth in macrophages. Parasite growth did not significantly change in the absence of LDLR or when LDL was exogenously supplemented. Lovastatin and compactin, both inhibitors of hydroxymethylglutaryl-CoA (HMG-CoA) reductase in the mevalonate pathway, significantly inhibited T. gondii growth in both wild-type and LDLR-knockout macrophages....
Palavras-chave: Cholesterol; Lipid metabolism; Macrophage; Parasitology; Toxoplasma gondii.
Ano: 2011 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3583
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Effect of fat-soluble components from sunflower on lipid metabolism in rats OAK
FUKUSHIMA, Michihiro; NAKANO, Masuo; 福島, 道広; 中野, 益男.
http://www.obihiro.ac.jp/~library/kenkyu.html
Palavras-chave: F344 rats; Sunflower fat-soluble component; Cholesterol; HDL-cholesterol; Triacylglycerol.
Ano: 1994 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3780
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生菌製剤投与によるラットの脂質代謝 OAK
福島, 道広; 中野, 益男; FUKUSHIMA, Michihiro; NAKANO, Masuo.
Palavras-chave: ラット; 生菌製剤; 腸内細菌叢; コレステロール; 胆汁酸; Rat; Probiotic; Faecal microflora; Cholesterol; Bile acid.
Ano: 1996 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/1347
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Synthetic retinoid Am80 controls growth of intracellular Toxoplasma by inhibiting acquisition and synthesis of cholesterol in macrophages OAK
Ihara, F.; Nshikawa, Y..
Palavras-chave: Toxoplasma gondii; Cholesterol; Triacylglycerols.
Ano: 2014 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4091
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Preparation method modulates hypocholesterolaemic responses of potato peptides OAK
Liyanage, Ruvini; Minamino, Saori; Nakamura, Yumi; Shimada, Ken-ichiro; Sekikawa, Mitsuo; Sasaki, Keiko; Ohba, Kiyoshi; Jayawardana, Barana Chaminda; Shibayama, Shin-ichi; Fukushima, Michihiro; 福島, 道広; 島田, 謙一郎; 関川, 三男.
In this study we compared the hypocholesterolaemic ability of two potato peptide preparations in rats. Experimental groups were fed for 4 weeks, with casein as the basal diet, in comparison with two diets containing 20% potato peptide preparations PPS (Short hydrolysis preparation) and PPL (Long hydrolysis preparation). Serum total cholesterol and serum triglyceride level were lower in PPS-fed group compared with CN-and PPL-fed groups. Lower non-HDL cholesterol level (P<0.05) in both PPS-and PPL-fed groups, was followed by higher neutral sterol excretion, and higher hepatic LDL-R and SR-B1 mRNA level than the control. Hepatic SREBP-2 and HMG-CoA reductase mRNA level were higher in PPL-fed group compared with the CN-fed group (P<0.05). Caecal total...
Palavras-chave: Potato peptide; Cholesterol; Short chain fatty acid; Faecal steroid; Hepatic gene; Rat.
Ano: 2010 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2682
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Toxoplasma gondii modulates neutral lipid metabolism in macrophage J774 cells OAK
Kameyama, K; Nishimura, M; Ybañez, R.D.; Hiasa, J; Xuan, X; Nishikawa, Y; 玄, 学南; 西川, 義文.
Palavras-chave: Toxoplasma gondii; Cholesterol; Triacylglycerols; Lipid bodies.
Ano: 2011 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3129
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Amylomyces rouxii Strain CBS 438.76 Affects Cholesterol Metabolism in Cholesterol-Fed Rats OAK
FUKUSHIMA, Michihiro; HAN, Kyu-Ho; TANEICHI, Yae; IIJIMA, Setsuko; SHIMADA, Ken-ichiro; SAITOH, Katsuichi; ODA, Yuji; CHIJI, Hideyuki; SEKIKAWA, Mitsuo; 福島, 道広; 韓, 圭鎬; 島田, 謙一郎; 小田, 有二; 関川, 三男.
We examined the effects of Amylomyces rouxii, which is a mold found in some fermented foods in Indonesia, on serum cholesterol and hepatic LDL receptor mRNA in rats. Rats were fed a 0.5% cholesterol-enriched diet with (A. rouxii group) or without (control group) 30g/kg A. rouxii for 4 wk. There were no significant differences in the body weight, food intake or liver weight among the groups. However, the weight of the cecum in the A. rouxii-fed group was significantly higher than that in the control group. The cecal pH in the A. rouxii-fed group was significantly lower than that in the control group. Cecal acetic acid, propionic acid and total SCFA concentrations in the A. rouxii-fed group were significantly higher than those in the control group. The serum...
Palavras-chave: Rats; Amylomyces rouxii strain CBS 438.76; Cholesterol; Cholesterol 7α-hydroxylase mRNA; LDL receptor mRNA.
Ano: 2005 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2911
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