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| Visentainer,J.E.L.; Lieber,S.R.; Persoli,L.B.L.; de Souza Lima,S.C.B.; Vigorito,A.C.; Aranha,F.J.P.; Eid,K.A.B.; Oliveira,G.B.; Miranda,E.C.M.; de Souza,C.A.. |
| The purpose of the present study was to evaluate the mixed lymphocyte culture as a predictive assay of acute and chronic graft-versus-host disease (GVHD). We studied 153 patients who received a first bone marrow transplantation from human leukocyte antigen-identical siblings. Acute GVHD was observed in 26 of 128 (20.3%) patients evaluated and chronic GVHD occurred in 60 of 114 (52.6%). One-way mixed lymphocyte culture (MLC) assays were performed by the standard method. MLC results are reported as the relative response (RR) from donor against patient cells. The responses ranged from -47.0 to 40.7%, with a median of 0.5%. The Kaplan-Meier probability of developing GVHD was determined for patients with positive and negative MLC. There was no significant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mixed lymphocyte culture; Allogeneic stem cell transplantation; Chronic graft-versus-host disease. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000500009 |
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