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The marine bacteria Cobetia marina DSMZ 4741 synthesizes an unexpected K-antigen-like exopolysaccharide ArchiMer
Lelchat, Florian; Cerantola, Stephane; Brandily, Christophe; Colliec-jouault, Sylvia; Baudoux, Anne-claire; Ojima, Takao; Boisset, Claire.
We have studied the exopolysaccharide produced by Cobetia marina DSMZ 4741, a marine bacterium isolated from coastal seawater. This strain is able to produce a polysaccharide in presence of carbon sources as glucose, mannitol and alginate. The maximum production occurs in aerobic condition, during the end of the exponential phase. The polymer is a non-viscous, acidic heteropolysaccharide of 270 kDa constituted of a repeating unit of: →2)-β-D-Ribf-(1→4)-[7,8-O-(Pyr)]-α-D-KDOp-(2→ This kind of chemical structure is generally related to K-antigen polysaccharide of pathogenic Escherichia coli strains. This is the first time this type of EPS is described from a marine bacterium. Moreover the polysaccharide exhibits a pyruvate substitution on its...
Tipo: Text Palavras-chave: Bacterial exopolysaccharides; K-antigen; Cobetia marina; KDO; Marine polysaccharide.
Ano: 2015 URL: https://archimer.ifremer.fr/doc/00254/36494/35038.pdf
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Antibiofilm activity of Cobetia marina filtrate upon Staphylococcus epidermidis catheter-related isolates BJM
Trentin,D.S; Gorziza,D. F; Abraham,W.R; Antunes,A.L.S; Lerner,C; Mothes,B; Termignoni,C; Macedo,A.J.
We report the antibiofilm activity by the sponge-associated bacterium Cobetia marina upon Staphylococcus epidermidis clinical isolates obtained from central venous catheters. Antibiofilm activity/antimicrobial susceptibility correlation might predict the action of the metabolite(s) upon Staphylococcus epidermidis in the clinic, making it a possible adjuvant in therapies against biofilm-associated infections.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biofilms; Antibiofilm activity; Staphylococcus epidermidis; Cobetia marina; Darwinella sp.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400013
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