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| Sauvage, Christopher; Bierne, N; Lapegue, Sylvie; Boudry, Pierre. |
| DNA sequence polymorphism and codon usage bias were investigated in a set of 41 nuclear loci in the Pacific oyster Crassostrea gigas. Our results revealed a very high level of DNA polymorphism in oysters, in the order of magnitude of the highest levels reported in animals to date. A total of 290 single nucleotide polymorphisms (SNPs) were detected, 76 of which being localised in exons and 214 in non-coding regions. Average density of SNPs was estimated to be one SNP every 60 bp in coding regions and one every 40 bp in non-coding regions. Non-synonymous substitutions contributed substantially to the polymorphism observed in coding regions. The non-synonymous to silent diversity ratio was 0.16 on average, which is fairly higher to the ratio reported in other... |
| Tipo: Text |
Palavras-chave: Crassostrea gigas; Codon bias; Genetic diversity; SNP. |
| Ano: 2007 |
URL: http://archimer.ifremer.fr/doc/2007/publication-3417.pdf |
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