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| Monnerat,Bruno Zanotelli; Cerutti Junior,Crispim; Caniçali,Sheila Cristina; Motta,Tânia Reuter. |
| We designed a retrospective cohort study to identify factors associated with HIV-1 related lipodystrophy at a tertiary HIV-care center in Vitória, ES, Brazil. Inclusion criteria were documented HIV diagnosis, anti-retroviral therapy and age above 17 years. Highly active antiretroviral therapy (HAART) was initially the exposure variable, but a second analysis was also performed, as a nested case-control, based on the presence or absence of lipodystrophy. Use of protease inhibitors (PI) was associated with an increase in serum triglycerides (243.7 ± 189 mg/dL vs. 172.7 ± 131 mg/dL, p = 0.015), but not of total cholesterol (TC) or HDL fraction levels. Non-nucleoside reverse transcriptase inhibitors (NNRTI) were associated with an increase in serum TC (180.6 ±... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lipodystrophy; Dyslipidemia; Brazil; AIDS; ARV therapy; Cohort study. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400002 |
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| Cardoso,V.C.; Simões,V.M.F.; Barbieri,M.A.; Silva,A.A.M.; Bettiol,H.; Alves,M.T.S.S.B.; Goldani,M.Z.. |
| We describe three birth cohort studies, respectively carried out in 1978/79 and 1994 in Ribeirão Preto, a city located in the most developed region of Brazil, and in 1997/98 in São Luís, a city located in a less developed region. The objective of the present report was to describe the methods used in these three studies, presenting their history, methodological design, objectives, developments, and difficulties faced along 28 years of research. The first Ribeirão Preto study, initially perinatal, later encompassed questions regarding the repercussions of intrauterine development on future growth and chronic adult diseases. The subjects were evaluated at birth (N = 6827), at school age (N = 2861), at the time of recruitment for military service (N = 2048),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cohort study; Epidemiological methods; Public health; Perinatal health; Sociodemographic conditions. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000900003 |
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| Hailpern, Susan M.; Visintainer, Paul F.. |
| Logistic regression is perhaps the most widely used method for adjustment of confounding in epidemiologic studies. Its popularity is understandable. The method can simultaneously adjust for confounders measured on different scales; it provides estimates that are clinically interpretable; and its estimates are valid in a variety of study designs with few underlying assumptions. To those of us in practice settings, several aspects of applying and interpreting the model, however, can be confusing and counterintuitive. We attempt to clarify some of these points through several examples. We apply the method to a study of risk factors associated with periventricular leucomalacia and intraventricular hemorrhage in neonates. We relate the logit model to... |
| Tipo: Journal Article |
Palavras-chave: Cc; Cci; Cs; Csi; Logistic; Logit; Relative risk; Case–control study; Odds ratio; Cohort study; Research Methods/ Statistical Methods. |
| Ano: 2003 |
URL: http://purl.umn.edu/116084 |
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