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	Provedor de dados BABT (1) BJMBR (1) Autor Martínez Morillo,Manuel (1) Ruiz-Gómez,Antonio (1) Ruiz-Gómez,Miguel J. (1) Tian,Meili (1) Yan,Xinpeng (1) Yang,Shuang (1) Mais... Palavra-chave Colon carcinoma (2) Caspases (1) Cell growth (1) DNA damage (1) Deterministic (1) Icariin (1) Mechanism (1) P53 (1) Simulation (1) Stochastic (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2018 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Stochastic modeling for a better approach of the in vitro observed growth of colon adenocarcinoma cells BABT Ruiz-Gómez,Miguel J.; Ruiz-Gómez,Antonio; Martínez Morillo,Manuel. The definition of a stochastic model that reflects the cell growth and the use of computer software could be very useful in modelling the cell behaviour due to the possibility to introduce alterations in biology parameters to obtain different growth patterns without the use of laboratory material. Human colon adenocarcinoma cells were cultured and a growth curve was made by daily count of the cell number. Pielou modelling was applied for stochastic simulation of deterministic growth, making stochastic the cell division, the death rates and the transition time between division and death, by using different probabilities. A greater growth was produced when the cell division rate increased, considering the density dependence constant. In contrast, a lower... Tipo: Info:eu-repo/semantics/article Palavras-chave: Colon carcinoma; Cell growth; Stochastic; Deterministic; Simulation. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000300006 Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities BJMBR Tian,Meili; Yang,Shuang; Yan,Xinpeng. Icariin has been reported to possess high anticancer activity. Colon carcinoma is one of the leading causes of cancer-related mortality worldwide. Here, the anticancer activity of icariin against HCT116 colon carcinoma cells and the possible underlying mechanism were studied. The trypan blue staining assay, wound healing assay, clonogenic assay, CCK-8 assay, and Annexin V-FITC/PI double staining method were carried out to determine the changes of HCT116 cell growth and migration. mRNA and protein expressions were determined by quantitative real-time PCR and western blot, respectively. Moreover, small interfering RNA (siRNA) plasmid was used to examine the role of p53 in icariin-induced apoptosis in HCT116 cells. Icariin significantly suppressed colon... Tipo: Info:eu-repo/semantics/article Palavras-chave: Colon carcinoma; Icariin; Mechanism; P53; DNA damage; Caspases. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000605 Registros recuperados: 2 Primeira ... 1 ... Última

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