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Facundo,H.T.F.; Brandt,C.T.; Owen,J.S.; Lima,V.L.M.. |
Schistosoma mansoni causes liver disease by inducing granulomatous inflammation. This favors formation of reactive oxygen species, including superoxide ions, hydrogen peroxide and hydroxyl radicals all of which may induce lipid peroxidation. We have evaluated lipid peroxidation in 18 patients with hepatosplenic schistosomiasis mansoni previously treated with oxamniquine followed by splenectomy, ligature of the left gastric vein and auto-implantation of spleen tissue, by measuring levels of erythrocyte-conjugated dienes and plasma malondialdehyde (MDA). Age-matched, healthy individuals (N = 18) formed the control group. Erythrocyte-conjugated dienes were extracted with dichloromethane/methanol and quantified by UV spectrophotometry, while plasma MDA was... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Lipid peroxidation; Conjugated dienes; Malondialdehyde; Schistosomiasis mansoni. |
Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000700003 |
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Caetano,Ana Carla da Silva; Araújo,Cristiane Rodrigues de; Lima,Vera Lúcia Arroxelas Galvão de; Maciel,Maria Inês Sucupira; Melo,Enayde de Almeida. |
This study was carried out to evaluate the antioxidant capacity of the agro-industrial waste from acerola. Hydroacetone, hydroethanolic, and hydromethanolic extracts were obtained using the sequential extraction process, and they were screened for their free radical DPPH (1,1-diphenyl-2-picrilhidrazil) and ABTS+ (2,2'-azino-bis-(3-etilbenzotiazolin 6-sulfonic acid) scavenging activity and their effect on the linoleic acid peroxidation by the ferric thiocyanate method. Soybean oil with the addition of the extracts (200 ppm) was submitted to Schaal oven test (60 °C, 28 days), in which the samples were analyzed for peroxide value and conjugated dienes. Hydroethanolic and hydromethanolic extracts exhibited good DPPH scavenging activity (low value of EC50 and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; DPPH; ABTS; Ferric thiocyanate; Peroxide value; Conjugated dienes; Acerola fruit waste. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612011000300034 |
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