Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BJMBR (4) Anais da ABC (AABC) (1) Genet. Mol. Biol. (1) Autor Brañes,M.C. (2) Martínez,A.D. (2) Sáez,J.C. (2) Abdelhay,Eliana (1) Bodi,Estevão (1) Borojevic,Radovan (1) Campos-de-Carvalho,A.C. (1) Carvalho,Antônio C. Campos de (1) Carvalho,Marcelo A. (1) Cofre,Jaime (1) Corvalán,L.A. (1) Eugenín,E.A. (1) González,H. (1) González,H.E. (1) Haefliger,J.-A. (1) Hurtado,Sandra P. (1) Meda,P. (1) Palisson,F. (1) Rozental,R. (1) Spray,D.C. (1) Mais... Palavra-chave Connexins (6) Gap junctions (5) Blood pressure (1) Bone marrow (1) Carboxyl terminal tail (1) Cardiovascular system (1) Cell contacts (1) Cell-cell communication (1) Cell-to-cell communication (1) Deoxycorticosterone (1) Distensibility (1) Dorso-ventral axis (1) Early development in amphibians (1) Heart (1) Hematopoiesis (1) Hypertension (1) Immune system (1) Inflammatory response (1) Native immune response (1) Nitric oxide (1) Mais... Tipo do documento Info:eu-repo/semantics/article (6) Ano 2007 (1) 2004 (1) 2000 (3) 1998 (1) País Brazil (6) Idioma Inglês (6)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 6 Primeira ... 1 ... Última Connexins in the early development of the African clawed frog Xenopus laevis (Amphibia): The role of the connexin43 carboxyl terminal tail in the establishment of the dorso-ventral axis Genet. Mol. Biol. Cofre,Jaime; Abdelhay,Eliana. Connexins are a family of related proteins identified in vertebrate forming gap junctions, which mediate cell-to-cell communication in early embryos, with an important role in establishing embryonic asymmetry and ‘communication compartments’. By in situ hybridization, immunocytochemistry, reverse transcriptase PCR (RT-PCR) and western blotting we show that a Cx43-like molecule is present in oocytes and embryos of the African clawed frog Xenopus laevis, with specific localization in the animal-vegetal axis. This specific distribution is suggestive for an important role for this protein in the establishment of the dorso-ventral axis. Antisense RNA and antibodies directed against rat carboxyl terminal tail of the Cx43 (CT-Cx43) and injected in 1-cell stage... Tipo: Info:eu-repo/semantics/article Palavras-chave: Connexins; Carboxyl terminal tail; Dorso-ventral axis; Early development in amphibians; Xenopus laevis. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000300030 Gap junctions in hematopoietic stroma control proliferation and differentiation of blood cell precursors Anais da ABC (AABC) Bodi,Estevão; Hurtado,Sandra P.; Carvalho,Marcelo A.; Borojevic,Radovan; Carvalho,Antônio C. Campos de. We examined gap junction communication in an in vitro model of hematopoiesis, using the murine bone marrow stroma cell line S-17, and primary cultures of murine marrow-derived blood cell precursors. S-17 cells express several connexins, the major one being connexin 43. Connexin expression and formation of functional gap junctions is modulated by stroma cell density. Transfection of S-17 cells with a vector containing connexin 43 sense or anti-sense sequences increased or decreased, respectively, connexin 43 synthesis and intercellular dye coupling. Under these conditions, modulation of gap junction-mediated communication modified the growth pattern of stroma itself, as well as the ability of the stroma to sustain hematopoiesis. Increased connexin 43... Tipo: Info:eu-repo/semantics/article Palavras-chave: Bone marrow; Hematopoiesis; Connexins; Gap junctions; S-17 cells. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652004000400009 Regulation of gap junctions by protein phosphorylation BJMBR Sáez,J.C.; Martínez,A.D.; Brañes,M.C.; González,H.E.. Gap junctions are constituted by intercellular channels and provide a pathway for transfer of ions and small molecules between adjacent cells of most tissues. The degree of intercellular coupling mediated by gap junctions depends on the number of gap junction channels and their activity may be a function of the state of phosphorylation of connexins, the structural subunit of gap junction channels. Protein phosphorylation has been proposed to control intercellular gap junctional communication at several steps from gene expression to protein degradation, including translational and post-translational modification of connexins (i.e., phosphorylation of the assembled channel acting as a gating mechanism) and assembly into and removal from the plasma membrane.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Gap junctions; Connexins; Protein phosphorylation; Sites of phosphorylation; Protein kinases; Cell-to-cell communication. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000500001 Gap junctions in cells of the immune system: structure, regulation and possible functional roles BJMBR Sáez,J.C.; Brañes,M.C.; Corvalán,L.A.; Eugenín,E.A.; González,H.; Martínez,A.D.; Palisson,F.. Gap junction channels are sites of cytoplasmic communication between contacting cells. In vertebrates, they consist of protein subunits denoted connexins (Cxs) which are encoded by a gene family. According to their Cx composition, gap junction channels show different gating and permeability properties that define which ions and small molecules permeate them. Differences in Cx primary sequences suggest that channels composed of different Cxs are regulated differentially by intracellular pathways under specific physiological conditions. Functional roles of gap junction channels could be defined by the relative importance of permeant substances, resulting in coordination of electrical and/or metabolic cellular responses. Cells of the native and specific... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cell contacts; Gap junctions; Connexins; Native immune response; Specific immune response; Inflammatory response. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000400011 Chronic hypertension alters the expression of Cx43 in cardiovascular muscle cells BJMBR Haefliger,J.-A.; Meda,P.. Connexin43 (Cx43), the predominant gap junction protein of muscle cells in vessels and heart, is involved in the control of cell-to-cell communication and is thought to modulate the contractility of the vascular wall and the electrical coupling of cardiac myocytes. We have investigated the effects of arterial hypertension on the expression of Cx43 in aorta and heart in three different models of experimental hypertension. Rats were made hypertensive either by clipping one renal artery (two kidney, one-clip renal (2K,1C) model) by administration of deoxycorticosterone and salt (DOCA-salt model) or by inhibiting nitric oxide synthase with NG-nitro-L-arginine methyl ester (L-NAME model). After 4 weeks, rats of the three models showed a similar increase in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cell-cell communication; Gap junctions; Connexins; Vasculature; Heart; Hypertension; Blood pressure; Renin; Deoxycorticosterone; Nitric oxide; Distensibility. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000400009 Gap junctions in the cardiovascular and immune systems BJMBR Rozental,R.; Campos-de-Carvalho,A.C.; Spray,D.C.. Gap junctions are clusters of intercellular channels directly connecting the cytoplasm of adjacent cells. These channels are formed by proteins named connexins and are present in all metazoan organisms where they serve diverse functions ranging from control of cell growth and differentiation to electric conduction in excitable tissues. In this overview we describe the presence of connexins in the cardiovascular and lympho-hematopoietic systems giving the reader a summary of the topics to be covered throughout this edition and a historical perspective of the discovery of gap junctions in the immune system. Tipo: Info:eu-repo/semantics/article Palavras-chave: Gap junctions; Cardiovascular system; Immune system; Connexins. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000400001 Registros recuperados: 6 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco