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Registros recuperados: 24 | |
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Vilela,Felippe Dantas; Lorenzo,Andrea Rocha de; Tura,Bernardo Rangel; Ferraiuoli,Giovanna Ianini; Hadlich,Marcelo; Barros,Marcelo Viana de Lima; Lima,Ana Beatriz Ribeiro; Meirelles,Vanderson. |
Current treatment for human immunodeficiency virus (HIV) infection has improved survival and allowed infected patients to develop atherosclerotic coronary artery disease (CAD). Specific strategies to reduce cardiovascular risk in the infected population have not been developed. It is necessary to know the magnitude of cardiovascular risk in this population. OBJECTIVES: This study aimed to assess cardiovascular risk using a well-known clinical score and to investigate coronary artery calcium scoring (CACS) in this population. METHODS: This was a cross-sectional study. Adults with HIV infection were studied. Demographic, clinical and anthropometric data, serum glucose and lipids were obtained. Cardiovascular risk was calculated through Framingham risk score... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coronary artery disease; HIV; Cardiovascular diseases; HIV protease inhibitors. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600004 |
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Costa,D. C.; Santi,G. L. de; Crescêncio,J. C.; Seabra,L. P.; Carvalho,E. E. V.; Papa,V.; Marques,F.; Gallo Junior,L.; Schmidt,A.. |
This study aimed to analyze the agreement between measurements of unloaded oxygen uptake and peak oxygen uptake based on equations proposed by Wasserman and on real measurements directly obtained with the ergospirometry system. We performed an incremental cardiopulmonary exercise test (CPET), which was applied to two groups of sedentary male subjects: one apparently healthy group (HG, n=12) and the other had stable coronary artery disease (n=16). The mean age in the HG was 47±4 years and that in the coronary artery disease group (CG) was 57±8 years. Both groups performed CPET on a cycle ergometer with a ramp-type protocol at an intensity that was calculated according to the Wasserman equation. In the HG, there was no significant difference between... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Wasserman equation; Cardiopulmonary exercise test; Coronary artery disease; Cardiovascular diagnostic techniques. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001201136 |
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de Miranda,E.J.F. Peixoto; Bittencourt,M.S.; Staniak,H.L.; Sharovsky,R.; Pereira,A.C.; Foppa,M.; Santos,I.S.; Lotufo,P.A.; Benseñor,I.M.. |
Data on the association between subclinical thyroid dysfunction and coronary artery disease (CAD) is scarce. We aimed to analyze the association between thyroid function and CAD using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). We included subjects with normal thyroid function (0.4-4.0 mIU/L, and normal free thyroxine, FT4, or 0.8 to 1.9 ng/dL), subclinical hypothyroidism (SCHypo; TSH>4.0 mIU/L and normal FT4), and subclinical hyperthyroidism (SCHyper; TSH<0.4 mIU/L and normal FT4) evaluated by coronary computed tomography angiography. We excluded individuals using medications that interfere in thyroid function or with past medical history of cardiovascular disease. Logistic regression models evaluated the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Thyroid disorders; Thyrotropin levels; Coronary artery disease; Coronary computed tomography angiography; Subclinical atherosclerosis; Cardiovascular disease. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000500609 |
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Acute thrombosis can be induced in rabbits by a triggering protocol using Russell's viper venom and histamine given after 8 months of a 1% cholesterol diet and balloon desendothelization. In the present study, we tested the hypothesis that aortic desendothelization performed 4 months before the triggering protocol without a high cholesterol diet is a highly effective and less expensive way of producing arterial atherosclerosis and thrombosis. Nineteen male New Zealand white rabbits on a normal diet were studied. The control group (N = 9) received no intervention during the 4-month observation period, while the other group (N = 10) was submitted to aortic balloon desendothelization using a 4F Fogarty catheter. At the end of this period, all animals were... |
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Palavras-chave: Endothelium; Histamine; Russell's viper venom; Coronary artery disease. |
Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000300017 |
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Machado,H.G.; Simões,R.P.; Mendes,R.G.; Castello,V.; Di Thommazo,L.; Almeida,L.B.; Lopes,S.L.B.; Catai,A.M.; Borghi-Silva,A.. |
The purpose of this study was to investigate the behavior of heart rate (HR) and HR variability (HRV) during different loads of resistance exercise (incline bench press) in patients with coronary artery disease (CAD) and healthy sedentary controls. Ten healthy men (65 ± 1.2 years, control group, CG) and 10 men with clinically stable CAD (66 ± 2.4 years, CADG) were recruited. A discontinuous progressive protocol was applied with an initial load of 10% of the maximum load achieved in the 1RM (1 repetition maximum) with increases of 10% until 30% 1RM was reached, which was followed by subsequent increases of 5% 1RM until exhaustion. HRV was analyzed by linear and non-linear methods. There was a significant reduction in rMSSD (CG: 20 ± 2 to 11 ± 3 ms; CADG: 19... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dynamic resistance exercise; Coronary artery disease; Heart rate variability; Autonomic nervous system; Upper limb exercise. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001200012 |
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Chequer,G.; Navarro,T.P.; Nascimento,B.R.; Falqueto,E.B.; Nascimento,D.C.; Alencar,M.C.N.; Mandil,A.; Saad,J.A.; Fonseca,C.P.; Ribeiro,A.L.. |
Endothelial function (EF) plays an important role in the onset and clinical course of atherosclerosis, although its relationship with the presence and extent of coronary artery disease (CAD) has not been well defined. We evaluated EF and the ST segment response to an exercise test in patients with a broad spectrum of CAD defined by coronary angiography. Sixty-two patients submitted to diagnostic catheterization for the evaluation of chest pain or ischemia in a provocative test were divided into three groups according to the presence and severity of atherosclerotic lesions (AL): group 1: normal coronaries (N = 19); group 2: CAD with AL <70% (N = 17); group 3: CAD with AL ≥70% (N = 26). EF was evaluated by the percentage of flow-mediated dilatation (%FMD)... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coronary artery disease; Endothelial function; Exercise testing. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000500003 |
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Prado,D.M.L.; Rocco,E.A.; Silva,A.G.; Rocco,D.F.; Pacheco,M.T.; Silva,P.F.; Furlan,V.. |
The oxygen uptake efficiency slope (OUES) is a submaximal index incorporating cardiovascular, peripheral, and pulmonary factors that determine the ventilatory response to exercise. The purpose of this study was to evaluate the effects of continuous exercise training and interval exercise training on the OUES in patients with coronary artery disease. Thirty-five patients (59.3±1.8 years old; 28 men, 7 women) with coronary artery disease were randomly divided into two groups: continuous exercise training (n=18) and interval exercise training (n=17). All patients performed graded exercise tests with respiratory gas analysis before and 3 months after the exercise-training program to determine ventilatory anaerobic threshold (VAT), respiratory compensation... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coronary artery disease; Exercise; Cardiorespiratory fitness; Ventilatory efficiency. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000200703 |
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Souza,D.R.S.; Nakachima,L.; Biagioni,R.B.; Nakazone,M.A.; Pinhel,M.A.S.; Trindade,D.M.; Mafra,V.T.; Tácito,L.H.B.; Martin,J.F.V.; Pinheiro Júnior,S.; Brandão,A.C.. |
Apolipoprotein E (apoE - e2, e3, e4 alleles) plays a role in the regulation of lipid metabolism, with the e4 considered to be a risk factor for coronary artery disease (CAD). We aimed to evaluate the apoE polymorphisms in Brazilians with CAD and their influence on the lipid profile and other risk factors (hypertension, diabetes mellitus, smoking). Two hundred individuals were examined: 100 patients with atherosclerosis confirmed by coronary angiography and 100 controls. Blood samples were drawn to determine apoE polymorphisms and lipid profile. As expected, the e3 allele was prevalent in the CAD (0.87) and non-CAD groups (0.81; P = 0.099), followed by the e4 allele (0.09 and 0.14, respectively; P = 0.158). The e3/3 (76 and 78%) and e3/4 (16 and 23%) were... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Apolipoprotein E polymorphism; Coronary artery disease; Lipid profile. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200005 |
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Almeida,S.; Hutz,M.H.. |
We examined the association of three established single nucleotide polymorphisms, IVS1-397T>C, IVS1-351A>G, and +261G>C, in the ESR1 gene with the prevalence and severity of coronary atherosclerosis in a southern Brazilian population of European ancestry. Three hundred and forty-one subjects (127 women and 214 men) with coronary artery disease (CAD) were classified as having significant disease (CAD+ patient group) when they showed 60% or more luminal stenosis in at least one coronary artery or major branch segment at angiography; patients with 10% or less luminal stenosis were considered to have minimal CAD (CAD- patient group). The control sample consisted of 142 subjects (79 women and 63 men) without significant disease, in whom coronary... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ESR1 polymorphisms; Coronary artery disease; Estrogen; Hormonal status. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400004 |
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Fuchs,A.R.C.N.; Meneghelo,R.S.; Stefanini,E.; De Paola,A.V.; Smanio,P.E.P.; Mastrocolla,L.E.; Ferraz,A.S.; Buglia,S.; Piegas,L.S.; Carvalho,A.A.C.. |
Myocardial ischemia may occur during an exercise session in cardiac rehabilitation programs. However, it has not been established whether it is elicited when exercise prescription is based on heart rate corresponding to the anaerobic threshold as measured by cardiopulmonary exercise testing. Our objective was to determine the incidence of myocardial ischemia in cardiac rehabilitation programs according to myocardial perfusion SPECT in exercise programs based on the anaerobic threshold. Thirty-nine patients (35 men and 4 women) diagnosed with coronary artery disease by coronary angiography and stress technetium-99m-sestamibi gated SPECT associated with a baseline cardiopulmonary exercise test were assessed. Ages ranged from 45 to 75 years. A second... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Exercise test; Anaerobic threshold; Myocardial ischemia; Coronary artery disease; Technetium; 99mTc-sestamibi. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000300008 |
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Zhang,Y.; Ling,Z.Y.; Deng,S.B.; Du,H.A.; Yin,Y.H.; Yuan,J.; She,Q.; Chen,Y.Q.. |
Associations between polymorphisms of the CD36 gene and susceptibility to coronary artery heart disease (CHD) are not clear. We assessed allele frequencies and genotype distributions of CD36 gene polymorphisms in 112 CHD patients and 129 control patients using semi-quantitative polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analysis. Additionally, we detected CD36 mRNA expression by real-time quantitative PCR, and we quantified plasma levels of oxidized low-density lipoprotein (ox-LDL) using an enzyme-linked immunosorbent assay (ELISA). There were no significant differences between the two groups (P>0.05) in allele frequencies of rs1761667 or in genotype distribution and allele frequencies of rs3173798. The genotype... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coronary artery disease; CD36; Rs1761667; Rs3173798; Single nucleotide polymorphism; Ox-LDL. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001000895 |
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Chalela,W.A.; Kreling,J.C.; Falcão,A.M.; Hueb,W.; Moffa,P.J.; Pereyra,P.L.A.; Ramires,J.A.F.. |
Controversy exists regarding the diagnostic accuracy, optimal technique, and timing of exercise testing after percutaneous coronary intervention. The objectives of the present study were to analyze variables and the power of exercise testing to predict restenosis or a new lesion, 6 months after the procedure. Eight-four coronary multi-artery diseased patients with preserved ventricular function were studied (66 males, mean age of all patients: 59 ± 10 years). All underwent coronary angiography and exercise testing with the Bruce protocol, before and 6 months after percutaneous coronary intervention. The following parameters were measured: heart rate, blood pressure, rate-pressure product (heart rate x systolic blood pressure), presence of angina, maximal... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Exercise test; Coronary artery disease; Percutaneous transluminal coronary angioplasty; Coronary multi-artery disease. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400007 |
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Rodrigues,A.N.; Moyses,M.R.; Bissoli,N.S.; Pires,J.G.P.; Abreu,G.R.. |
Epidemiological and clinical evidence suggests that a judicious diet, regular physical activity and blood pressure (BP) monitoring must start in early childhood to minimize the impact of modifiable cardiovascular risk factors. This study was designed to evaluate BP and metabolic parameters of schoolchildren from Vitória, Espírito Santo State, Brazil, and correlate them with cardiovascular risk factors. The study was conducted on 380 students aged 10-14 years (177 boys, 203 girls) enrolled in public schools. Baseline measurements included body mass index, BP and heart rate. The students were submitted to exercise spirometry on a treadmill. VO2max was obtained from exercise testing to voluntary exhaustion. Fasting serum total cholesterol (TC), LDL-C, HDL-C,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cardiovascular risk factors; Arterial hypertension; Primary prevention; Coronary artery disease; Obesity; Schoolchildren. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001200015 |
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Registros recuperados: 24 | |
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