| In the context of the fish farming industry needing to substitute the animal food (meal and oil) by vegetable ingredients, the main objective of this thesis was to study the long-term effects of a diet exclusively composed by plant products on the metabolism of the european sea bass (Dicentrarchus labrax) and more particularly, on its capacity to biosynthesis the Highly Unsaturated Fatty Acids (HUFA) from the PolyUnsaturated Fatty acids (PUFA) brought by this vegetal diet. Our transcriptomic approaches showed that the use of a plant food disrupted the lipids metabolism (cholesterol and fatty acids) and the energy metabolism (carbohydrates, amino acids) in the liver, but also affected other physiological processes such as the immune system. In spite of the... |
