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| Oliveira,David Moraes de; Silveira,Márcia Maria Ferreira da; Andrade,Emanuel Sávio de Souza; Sobral,Ana Paula Veras; Martins-Filho,Paulo Ricardo Saquete; Santos,Thiago de Santana; Oliveira,Patrícia Leimig Amorim de; Peixoto,Aline Carvalho; Santos,Jadson Alípio Santana de Souza; Piva,Marta Rabello. |
| This study investigated the immunodetection of PTCH in epithelial components of dental follicles associated with impacted third molars without radiographic signs of pathosis. One hundred and five specimens of dental follicles associated with impacted third molars with incomplete rhizogenesis (between Nolla's stage 6 and 9) were surgically removed from 56 patients. Epithelial cell proliferation was determined by using immunohistochemical labeling. Statistical analysis was performed using Fisher exact test and a level of significance of 5%. Of the 105 dental follicles collected, 3 were PTCH-positive. The specimens with squamous metaplasia and epithelial hyperplasia had higher rates of positivity for PTCH, as well as those with active remnants of odontogenic... |
| Tipo: Journal article |
Palavras-chave: Immunohistochemistry; Dental follicle; Odontogenic epithelial; PTCH. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100018 |
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| Kömerik,Nurgül; Tufan,Alper; Kapucuoglu,Nilgün. |
| The aim of this comparative observational study was to compare the proliferative activity of dental follicles surrounding impacted maxillary canines and mandibular third molars. Following extraction, forty follicles of the impacted mandibular third molars and 40 follicles of the impacted maxillary canines were removed. Epithelial cell proliferative activity of these samples was assessed using immunohistochemical labeling for Ki-67, minichromosome maintenance 2 (MCM-2) protein and epithelial growth factor receptor (EGFR). Intensity and extent of Ki-67, MCM-2 and EGFR expressions were evaluated by a scoring formula. The lining epithelium of the maxillary canine follicles had mean scores of 4.65±0.27 for Ki-67, 1.25±0.33 for MCM-2 and 7.30±0.23 for EGFR which... |
| Tipo: Journal article |
Palavras-chave: Dental follicle; Ki-67; MCM-2; EGFR; Immunohistochemistry. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400028 |
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