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| Registros recuperados: 26 | |
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| Segatto,Ana Lúcia Anversa; Diesel,José Francisco; Loreto,Elgion Lucio Silva; da Rocha,João Batista Teixeira. |
| Abstract The use of Drosophila as a scientific model is well established, but the use of cockroaches as experimental organisms has been increasing, mainly in toxicology research. Nauphoeta cinerea is one of the species that has been studied, and among its advantages is its easy laboratory maintenance. However, a limited amount of genetic data about N. cinerea is available, impeding gene identification and expression analyses, genetic manipulation, and a deeper understanding of its functional biology. Here we describe the N. cinerea fat body and head transcriptome, in order to provide a database of genetic sequences to better understand the metabolic role of these tissues, and describe detoxification and stress response genes. After removing low-quality... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nauphoeta cinerea; Transcriptome assembly; Fat body; Detoxification. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000400713 |
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| Miramand, Pierre; Bustamante, Paco; Bentley, Daniel; Koueta, Noussithe. |
| The developmental changes in the concentration of 8 essential and non-essential heavy metals (Ag, Cd, Cu, Co, Fe, Pb, V, Zn) in the tissues (digestive gland, cuttlebone and whole animal) of the common cuttlefish Sepia officinalis collected in the bay of the river Seine were monitored from the end of the embryogenesis until the adult reproductive stage. Compared to embryos, juveniles after hatching displayed much higher concentrations of Ag, Cu, Fe and Zn, suggesting an efficient incorporation from seawater. Conversely, the amounts of Cd, Pb and V in hatchlings remained constant suggesting that these metals are barely bioavailable for juveniles. Once the juveniles start to feed, the digestive gland appears to play a major role in the storage of all metals.... |
| Tipo: Text |
Palavras-chave: Embryogenesis; Sexual maturity; Cephalopods; Detoxification; Bioaccumulation; Trace element. |
| Ano: 2006 |
URL: http://archimer.ifremer.fr/doc/2006/publication-2330.pdf |
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| Lassus, Patrick; Bardouil, Michele; Baron, Regis; Berard, Jean-baptiste; Masselin, Pierre; Truquet, Philippe; Pitrat, Jp. |
| Shellfish production, and production of marine bivalve molluscs in particular, is the main form of marine aquaculture in the European Union, with a production estimated at 1,200,000 tons in 1999 (Food and Agricultural Organization). Moreover, aquaculture production is rapidly expanding throughout Europe and is becoming a major economic resource in developing areas such as Northern Greece, Ireland, and northwestern Spain. These shellfish, mainly mussels, oysters, and clams, are produced in a natural environment. Due to variations in their environment, these otherwise edible species may however become unsafe for human consumption. Potential problems are amplified due to the nature of shellfish themselves: as they are filter feeders, they consume large... |
| Tipo: Text |
Palavras-chave: Detoxification; PSP toxin; Toxic algae; Bioaccumulation; Contaminant; Clam; Mussel; Oyster; Shellfish culture. |
| Ano: 2005 |
URL: http://archimer.ifremer.fr/doc/2005/publication-2271.pdf |
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| Bustamante, Paco; Bertrand, M; Boucaud Camou, E; Miramand, Pierre. |
| The subcellular fractionation of the digestive gland cells of the common cuttlefish Sepia officinalis was performed to investigate the distribution of metals between organelles and cytosol and the different cytosolic fractions separated by gel-filtration chromatography. Total metal concentrations vary over 3 orders of magnitude, ranging from dwt for Pb to dwt for Zn. With the exception of Cd, Co, and Cu, metals were mostly bound to the organelles. Whereas no specific organelle compartment was found for Mn, Ph, and Zn, Fe was mainly associated with nucleus, brown body, and "boule" fraction (i.e., 52%) and 44% of the total Ag was contained in the lysosomal and mitochondria enriched fraction. The link of metals with hydrosoluble proteins in the cytosolic... |
| Tipo: Text |
Palavras-chave: Sepia officinalis; Chromatography; Metallothionein; Detoxification; Trace element; Metal; Cephalopod. |
| Ano: 2006 |
URL: http://archimer.ifremer.fr/doc/2006/publication-2532.pdf |
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| Chatel, Annelle; Faucet-marquis, Virginie; Gourlay-france, Catherine; Pfohl-leszkowicz, Annie; Hubert, Francoise. |
| The aim of the present study was to confirm the relevance of studying DNA adduct formation in a field study. In that context, freshwater mussels Dreissena polymorpha, collected in a reference station, were transplanted in different sites with a pollution gradient. After one and two months, mussels were collected and DNA adduct formation was analyzed using the 32P post labelling technique on both gills and digestive glands. In addition, the expression of genes involved in the detoxification system (catalase (CAT), superoxide dismutase (SOD), glutathione S-transferase (GST), HSP70, aryl hydrocarbon receptor (AHR), P glycoprotein (PgP), metallothionein (MT)) was assessed by RT-PCR. DNA adducts were observed at amount comparable to data from literature.... |
| Tipo: Text |
Palavras-chave: Biomarker; Pollution; DNA adducts; Detoxification; Dreissena polymorpha; RT-PCR. |
| Ano: 2015 |
URL: https://archimer.ifremer.fr/doc/00195/30639/32450.pdf |
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| Medhioub, Walid; Gueguen, Marielle; Lassus, Patrick; Bardouil, Michele; Truquet, Philippe; Sibat, Manoella; Nejib, Medhioub; Philippe, Soudant; Mejdeddine, Kraiem; Amzil, Zouher. |
| In the Gulf of Gabes (Tunisia, Eastern Mediterranean sea), the grooved carpet shell Ruditapes decussatus has been seen to contain persistent levels of gymnodimine (GYM) for several years. The present experimental work represents the first attempt to assess detoxification kinetics of fast-acting toxins (FAT) in marine molluscs fed specific diets of non-toxic algae (Isochrysis galbana). To find an optimal detoxification method, two experiments were performed in which clams were first fed the toxic dinoflagellate Karenia selliformis to artificially contaminate them with GYM, thus simulating the effect of natural toxic episodes. As a second step, the same clams were fed a non-toxic algae, I. galbana. to speed up the detoxification process. Changes in toxin... |
| Tipo: Text |
Palavras-chave: Ruditapes decussates; Grooved carpet shell; Karenia selliformis; Gymnodimine; Toxicity; Detoxification. |
| Ano: 2010 |
URL: http://archimer.ifremer.fr/doc/2010/publication-7488.pdf |
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| Gueguen, Marielle; Bardouil, Michele; Baron, Regis; Lassus, Patrick; Truquet, Philippe; Massardier, Julie; Amzil, Zouher. |
| Contamination of shellfish by paralytic shellfish poisoning ( PSP) toxins poses an economic threat to shellfish farmers. As contaminated shellfish cannot be harvested for long periods of time, it would be very useful to develop processes to optimise and shorten their detoxification. In this study, Pacific oysters Crassostrea gigas were first experimentally contaminated over a period of 13 days with a continuous flow of toxic Alexandrium minutum cultures at concentrations ranging from 150 to 200 cell ml(-1) ( toxin content after 13 days of contamination 438 mu g STX equiv. 100 g(-1) wet weight). Then, two different detoxification treatments were tested and showed detoxification rates greater than those observed in coastal environments. The first treatment... |
| Tipo: Text |
Palavras-chave: Alexandrium minutum; Crassostrea gigas; Detoxification; Inorganic matter; Organic matter; PSP; Paralytic shellfish poisoning. |
| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/2008/publication-3896.pdf |
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| Kojadinovic, Jessica; Potier, Michel; Le Corre, Matthieu; Cosson, Richard P.; Bustamante, Paco. |
| Trace elements were analyzed in fish of commercial interest to determine their importance in marine systems of the Western Indian Ocean and their bioaccumulation patterns. The results are equivalent or lower than levels reported in ichthyofauna worldwide. Certain values of muscular Cd, Hg, Pb and Zn were, however, above thresholds for human consumption. Levels varied among tissues, species and fish length, but were seldom influenced by the nutritional condition of the fish, its gender and its reproductive status. Correlations between hepatic Hg and Se levels in Swordfish (r(2) = 0.747) and Yellowfin Tunas (r(2) = 0.226), and among metallothionein linking metals imply the existence of detoxification processes in these species. Level differences between fish... |
| Tipo: Text |
Palavras-chave: Guidelines; Detoxification; Contamination; Fish; Metals. |
| Ano: 2007 |
URL: http://archimer.ifremer.fr/doc/2007/publication-2490.pdf |
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| GAWADE,S. P.. |
| The photodynamic action of UV sensitized methylene blue (MB) was studied on the venom of Thailand cobra Naja siamensis. The reaction mixture comprising phosphate buffer (B), methylene blue (S), and venom protein (P) was exposed to UVR (ultra violet radiation) for 2 hours at 37°C. Stable excited species (S) were generated by photodynamic action. These in B environment produced reduced substates SH2 and photooxidised products PO in the presence of atmospheric oxygen. Increased absorbance (OD) of the reaction mixture after UVR with a corresponding loss of protein was suggested to be due to the formation of photooxidised venom products. The detoxification profile of venom protein using visible radiation in the presence of MB and oxygen appeared similar to the... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Thailand cobra; Naja siamensis; Photosensitization; Photooxidation; Detoxification. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200010 |
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| Ferreira Junior,R. S.; Nascimento,N.; Martinez,J. C.; Alves,J. B.; Meira,D. A.; Barraviera,B.. |
| ELISA was used to evaluate, follow, and compare the humoral immune response of Swiss mice during hyperimmunization with natural and Cobalt 60-irradiated (60Co) Crotalus durissus terrificus venom. Potency and neutralization were evaluated by in vitro challenges. After hyperimmunization, immunity was observed by "in vivo" challenge and the side effects were assessed. The animals immunization with one LD50 of the venom was on days one, 15, 21, 30, and 45, when blood samples were collected; the challenges occurred on the 60th day. Results showed that ELISA was efficient in evaluating, following, and comparing mouse immune response during hyperimmunization. Serum titers produced with natural venom were similar to those produced with irradiated venom.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hyperimmunization; Irradiation; Crotalus durissus terrificus; ELISA; Serum neutralization; Detoxification. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000300008 |
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| Ferreira Junior,R. S.; Nascimento,N.; Martinez,J. C.; Alves,J. B.; Meira,D. A.; Barraviera,B.. |
| ELISA was used to evaluate, accompany, and compare the humoral immune response of Swiss mice during hyperimmunization with native and Cobalt-60-irradiated (60Co) venoms of Bothrops jararaca, Bothrops jararacussu and Bothrops moojeni. Potency and neutralization were evaluated by in vitro challenges. After hyperimmunization, immunity was observed by in vivo challenge, and the side effects were assessed. The animals immunization with one LD50 of each venom occurred on days 1, 15, 21, 30, and 45, when blood samples were collected; challenges happened on the 60th day. Results showed that ELISA was efficient in evaluating, accompanying and comparing mouse immune response during hyperimmunization. Serum titers produced with natural venom were similar to those... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Venom; Irradiation; Bothrops; ELISA; Serum production; Detoxification. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000400006 |
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| Medhioub, W.; Amzil, Z.; Sudant, Ph.; Hamza, A.; Medhioub, M.N.; Kraiem, M.M.; Lassus, P.. |
| Depuis 1994 la prolifération de la micro algue toxique, Karenia selliformis, productrice de la gymnodimine (GYM), dans le golfe de Gabes (Sud de la Tunisie) contamine fréquemment les sites de production de la palourde Ruditapes decussatus et, d’une façon continue la lagune de Boughrara, entrainant ainsi l’arrêt de la commercialisation de cette espèce. La contamination des mollusques bivalves par les phycotoxines est un problème mondial qui nécessite d’apporter une solution. C’est dans ce cadre que s’inscrit ce travail qui a pour objectif l’étude de l’impact de l’alimentation à base de la microalgue fourrage Isochrysis galbana Tahitian clone (T.Iso) sur la cinétique de détoxification de la palourde contaminée naturellement. Les analyses de la toxine ont été... |
| Tipo: Journal Contribution |
Palavras-chave: Detoxification. |
| Ano: 2013 |
URL: http://hdl.handle.net/1834/5901 |
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| PAGNONCELLIJR.,F.D.B.; VIDAL,R.A.; TREZZI,M.M.; MACHADO,A.; GALLON,M.; XAVIER,E.; OLIVEIRA,M.C.. |
| ABSTRACT The objectives of this study were to determine the effect of herbicide ethoxysulfuron on the development of commom bean (Phaseolus vulgaris), to evaluate the impact of the herbicide on the crop grain yield and to determine the mechanism of tolerance of common bean to ethoxysulfuron. Field experiments were carried out with several doses of ethoxysulfuron to determine its effect on the grain yield of two varieties of common bean ("IPR Andorinha", "IPR Tangará"). The mechanism of plant tolerance was evaluated through several methods, including the analysis of the ALS enzyme sensitivity to herbicide and the use of P450 inhibitors (the insecticides malathion + chlorpyrifos) and the use of antidote (mefenpyr-diethyl). When the rate of ethoxysulfuron was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phaseolus vulgaris; Crop grain yield; ALS enzyme; Detoxification. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582016000300535 |
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| QUEIROZ,,A.R.S.; VIDAL,,R.A.; NAVA,,I.C.; PACHECO,,M.T.; FEDERIZZI,,L.C.; XAVIER,E.. |
| ABSTRACT Weeds are among the main constraints to high grain yield on hexaploid oat (Avena sativa), but there are few herbicides registered for weed control on this cereal crop. The objectives of this study were to evaluate the impact of the iodosulfuron-methyl on grain yield of elite oat cultivars and investigate the mechanism of oat tolerance to this herbicide. A field experiment conducted in 2012 demonstrated there was no difference on grain yield between cultivars URS Guará and URS Guria, when iodosulfuron-methyl was used up to 4.5 g ha-1. Likewise, experiments from 2013 have demonstrated that iodosulfuron-methyl, at 5 g ha-1, did not affect the oat grain yield of the genotype UFRGS 14, but affected it on the cultivars URS Guará and URS Guria. In 2014,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Avena sativa; Detoxification; Tolerance; Acetolactate synthase inhibitor. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582017000100227 |
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| Furtado,Rafael Nogueira; Pompeu,Roberto Cláudio Fernandes Franco; Cândido,Magno José Duarte; Pereira,Elzânia Sales; Lopes,Marcos Neves; Rogério,Marcos Cláudio Pinheiro. |
| ABSTRACT The effect of substituting soybean meal (SM) with four levels (0, 33, 67 and 100%) of detoxified castor cake (DCC) on intake, nutrient digestibility and nitrogen balance was evaluated in uncastrated, male, crossbred sheep in a randomised complete block design with four treatments and five replications. There was a decreasing linear effect from the levels of substitution on dry matter (DM), organic matter (OM) and crude protein (CP) intake, total carbohydrates (TC), non-fibrous carbohydrates (NFC) and total digestible nutrients (TDN), and on DM, OM and TC digestibility, for reductions of 2.04, 1.70, 0.35, 1.56, 1.89 and 1.67 g dia-1 and 0.34, 0.53 and 0.51 g kg-1 DM respectively, for each 1% SM substituted with DCC. DMI and NDFap expressed, in %BW... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biodiesel; Detoxification; Ricin; Ricinus communis; Nutritional value.. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902020000100412 |
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| Registros recuperados: 26 | |
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