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The carotid body of the spontaneous insulin-dependent diabetic rat BJMBR
Clarke,J.A.; Daly,M. de B.; Ead,H.W.; Hennessy,E.M..
The carotid bodies from adult spontaneous insulin-dependent diabetic rats (strain BB/S) were perfusion-fixed at normal arterial blood pressure with 3% phosphate-buffered glutaraldehyde and compared with the organs from control rats (strain BB/Sc) prepared in the same way. Serial 5-µm sections were cut, stained, and using an interactive image analysis system, were analysed to determine the volumes of the carotid body and its vascular and extravascular compartments. There was no evidence of systemic arterial disease in the carotid stem arteries in either group of animals, and the microvasculature of the organs appeared normal by light microscopy. The volume of the carotid body was unchanged 3 months after the onset of diabetes but was increased at 6 months....
Tipo: Info:eu-repo/semantics/other Palavras-chave: Diabetic rat; Carotid body; Quantitative morphology; Vascular compartment.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100013
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