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	Provedor de dados BABT (1) BJMBR (1) Genet. Mol. Biol. (1) Autor Amaral,A. (1) Amaral,Ademir (1) Borges,E. (1) Cadena,M. (1) Fernandes,T.S. (1) Fernandes,Thiago Salazar (1) Giorgio,Marina Di (1) Hwang,Suy (1) Lemos-Pinto,M.M.P. (1) Lima,Fabiana Farias de (1) Loyd,David C. (1) Mendes,Mariana Esposito (1) Mendonça,Julyanne Conceição Goes de (1) Santos,N. (1) Santos,Neide (1) Mais... Palavra-chave Dicentrics (3) Biodosimetry (1) Biological dosimetry (1) CABAS (1) Calibration curves (1) Chromosome contraction (1) Dose Estimate (1) Gamma radiation (1) Intercomparisons (1) Linear accelerator (1) Partial-body exposure (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2020 (1) 2015 (1) 2008 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Biodosimetry for dose assessment of partial-body exposure: a methodological improvement BABT Fernandes,Thiago Salazar; Loyd,David C.; Amaral,Ademir. This study has explored the possibility of combining culture times with extending the duration for which Colcemid is present in cell culture in order to obtain better dose estimations following partial-body exposures. Irradiated and unirradiated blood was mixed to simulate a partial-exposure. Dicentric frequencies and resultant dose estimations were compared from 48 and 72 h cultures with Colcemid added at the beginning, after 24 h or for the final 3 h. The frequencies of dicentrics in first division cells increased with the cell culture time, providing better dose estimations. Unwanted excessive contraction of chromosomes caused by prolonged contact with Colcemid was measured and ways to avoid this are discussed. It is suggested that the combination of a... Tipo: Info:eu-repo/semantics/article Palavras-chave: Biodosimetry; Partial-body exposure; Dicentrics; Chromosome contraction. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700016 A dose-response curve for biodosimetry from a 6 MV electron linear accelerator BJMBR Lemos-Pinto,M.M.P.; Cadena,M.; Santos,N.; Fernandes,T.S.; Borges,E.; Amaral,A.. Biological dosimetry (biodosimetry) is based on the investigation of radiation-induced biological effects (biomarkers), mainly dicentric chromosomes, in order to correlate them with radiation dose. To interpret the dicentric score in terms of absorbed dose, a calibration curve is needed. Each curve should be constructed with respect to basic physical parameters, such as the type of ionizing radiation characterized by low or high linear energy transfer (LET) and dose rate. This study was designed to obtain dose calibration curves by scoring of dicentric chromosomes in peripheral blood lymphocytes irradiated in vitro with a 6 MV electron linear accelerator (Mevatron M, Siemens, USA). Two software programs, CABAS (Chromosomal Aberration Calculation Software)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dicentrics; Calibration curves; Linear accelerator; CABAS; Dose Estimate. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001000008 Calibration curves by 60Co with low dose rate are different in terms of dose estimation – a comparative study Genet. Mol. Biol. Mendes,Mariana Esposito; Mendonça,Julyanne Conceição Goes de; Hwang,Suy; Giorgio,Marina Di; Lima,Fabiana Farias de; Santos,Neide. Abstract Biological dosimetry aims to estimate individual absorbed doses due ionizing radiation exposure. The dicentric chromosomes are considered the most specific biomarker for dose estimation. This study aimed to compare calibration curves for linear low energy transfer (LET) radiation built from low dose rates and whether they vary in terms of dose estimation. For that we did a search in the literature of all calibration curves produced with low dose rates and we simulated the dose estimation from pre-established dicentric’s frequencies. The information on methodologies and cytogenetic results of each study were analyzed. As expected dose rate influence β coefficients, especially at higher doses. However, we have seen that some doses were not... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dicentrics; Gamma radiation; Biological dosimetry; Intercomparisons. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000100108 Registros recuperados: 3 Primeira ... 1 ... Última

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