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	Provedor de dados Biol. Res. (2) Autor CARRASCO,MARIA ANGELICA (1) FRANZINI-ARMSTRONG,CLARA (1) JAIMOVICH,ENRIQUE (1) Palavra-chave Dihydropyridine receptors (2) CREB (1) Calcium release units (1) Early genes (1) Excitation-transcription (1) Inositol trisphosphate (1) Mitogen-activated kinases (1) Ryanodine receptors (1) Sarcoplasmic reticulum (1) Transverse tubules (1) Mais... Tipo do documento Journal article (2) Ano 2004 (1) 2002 (1) País Chile (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Functional implications of RyR-DHPR relationships in skeletal and cardiac muscles Biol. Res. FRANZINI-ARMSTRONG,CLARA. Dihydropyridine receptors (DHPRs) and ryanodine receptors (RyRs) interact during EC coupling within calcium release units, CRUs. The location of the two channels and their positioning are related to their role in EC coupling. als DHPR and RyR1 of skeletal muscle form interlocked arrays. Groups of four DHPRs (forming a tetrad) are located on alternate RyR1s. This association provides the structural framework for reciprocal signaling between the two channels. RyR3 are present in some skeletal muscles in association with RyR1 and in ratios up to 1:1. RyR3 neither induce formation of tetrads by DHPRs nor sustain EC coupling. RyR3 are located in a parajunctional position, in proximity of the RyR1-DHPR complexes, and they may be indirectly activated by calcium... Tipo: Journal article Palavras-chave: Calcium release units; Dihydropyridine receptors; Ryanodine receptors; Transverse tubules; Sarcoplasmic reticulum. Ano: 2004 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400003 IP3 dependent Ca2+ signals in muscle cells are involved in regulation of gene expression Biol. Res. JAIMOVICH,ENRIQUE; CARRASCO,MARIA ANGELICA. Potassium depolarization of cultured muscle cells was employed to study cellular responses linked to calcium signaling. Events occurring after depolarization include i) A transient increase of the IP3 mass (2-10s); ii) A slow calcium transient (5 to 25s) that propagates as a low concentration wave along the myotube showing a distinct calcium transient at the level of cell nuclei. Due to the presence of IP3 receptors both in the SR (A-band region) and in the nuclear envelope, these two events appear to be related; iii) Phosphorylation of mitogen activated kinases (ERK 1/2) and of the transcription factor CREB (30 s-10 min), as well as expression of the early genes c-fos, c-jun and egr-1 mRNA (5-15 min). Several independent pieces of evidence, including... Tipo: Journal article Palavras-chave: Excitation-transcription; Inositol trisphosphate; Mitogen-activated kinases; CREB; Early genes; Dihydropyridine receptors. Ano: 2002 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200010 Registros recuperados: 2 Primeira ... 1 ... Última

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