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Cutaneous periumbilical purpura in disseminated strongyloidiasis in cancer patients: a pathognomonic feature of potentially lethal disease? BJID
Salluh,Jorge I. F.; Bozza,Fernando A.; Pinto,Tatiana S.; Toscano,Luisa; Weller,Peter F.; Soares,Marcio.
Cutaneous manifestations in disseminated strongyloidiasis are infrequent but should raise the suspicion for its diagnosis. We retrospectively evaluated the charts of six patients with cancer and a proven diagnosis of disseminated strongyloidiasis. All patients had received prophylaxis with albendazole before starting antineoplastic therapy, which included high-dose steroids. They presented with septic shock, acute respiratory failure and characteristic purpuric periumbilical skin lesions. Strongyloides larvae were identified in tracheal aspirates (n=5), gastric aspirates (n=4), lung (n=2) and skin biopsies (n=2). All patients died despite antihelminthic therapy and intensive care support.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sepsis; Purpura; Cancer; Disseminated strongyloidiasis; Corticosteroids.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000500010
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Fatal Strongyloides stercoralis hyper-infection in a patient with multiple myeloma BJID
Yassin,Mohamed A; El Omri,Halima; Al-Hijji,Ibrahim; Taha,Ruba; Hassan,Reham; Aboudi,Kamal Al; El-Ayoubi,Hanadi.
Strongyloides stercoralis (S.S.) is a human intestinal parasite, which may lead to complicated strongyloidiasis. We report a case of disseminated strongyloidiasis following the treatment of myeloma. The patient developed skin lesions, respiratory distress, aseptic meningitis and bacterial and fungal sepsis. The diagnosis of strongyloidiasis was established through endotracheal tube secretions. Despite the treatment with Ivermectin and Albendazole, the outcome was fatal. The value of screening for strongyloidiasis is unclear but may be of benefit in patients with hematological malignancies from high endemic areas
Tipo: Info:eu-repo/semantics/report Palavras-chave: Acute respiratory failure; Disseminated strongyloidiasis; Myeloma; Steroids.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500019
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