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	Provedor de dados BJID (1) BJMBR (1) Autor Adkinson Jr.,N.F. (1) Arruda,Érico Antônio Gomes de (1) Carvalho,Paulo Germano de (1) Castro,F.M. (1) Galvão,C.E.S. (1) Kalil,J. (1) Lima,C.M.F. (1) Lima,Denise Girão Limaverde (1) Nagao-Dias,Aparecida Tiemi (1) Rabenhorst,Silvia Helena Barem (1) Ribeiro,Ilana Farias (1) Rodrigues,Raphael de Oliveira (1) Schroeder,J.T. (1) Silva,Silvia Fernandes Ribeiro da (1) Mais... Palavra-chave Drug allergy (2) Dendritic cells (1) HIV (1) IL-10 (1) Plasmacytoid dendritic cells (1) Polymorphism (1) Β-lactam hypersensivity (1) Mais... Tipo do documento Info:eu-repo/semantics/other (2) Ano 2014 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Interleukin-10 gene polymorphism (-1082G/A) and allergy to efavirenz in patients infected with human immunodeficiency virus BJID Rodrigues,Raphael de Oliveira; Carvalho,Paulo Germano de; Arruda,Érico Antônio Gomes de; Rabenhorst,Silvia Helena Barem; Silva,Silvia Fernandes Ribeiro da; Ribeiro,Ilana Farias; Lima,Denise Girão Limaverde; Nagao-Dias,Aparecida Tiemi. The aim of the present study was to investigate the association between polymorphism in the interleukin-10 gene promoter at position -1082 in human immunodeficiency virus-infected patients who had presented allergic reaction due to efavirenz. The study included 63 patients treated at the Hospital São José de Doenças Infecciosas, Fortaleza, Ceará, Brazil. Twenty-one patients who had presented allergic reaction to efavirenz were compared to 42 patients with no allergic reaction following exposure to this drug. Blood samples were collected for DNA extraction and submitted to the restriction fragment length polymorphism - polymerase chain reaction technique. The -1082AA genotype was significantly more frequent in allergic patients as compared to non-allergic... Tipo: Info:eu-repo/semantics/other Palavras-chave: HIV; Drug allergy; Polymorphism; IL-10. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400445 Functional changes of dendritic cells in hypersensivity reactions to amoxicillin BJMBR Lima,C.M.F.; Schroeder,J.T.; Galvão,C.E.S.; Castro,F.M.; Kalil,J.; Adkinson Jr.,N.F.. A better understanding of dendritic cell (DC) involvement in responses to haptenic drugs is needed, because it represents a possible approach to the development of an in vitro test, which could identify patients prone to drug allergies. There are two main DC subsets: plasmacytoid DC (pDC) and myeloid DC (mDC). β-lactams form hapten-carrier conjugates and may provide a suitable model to study DC behavior in drug allergy reactions. It has been demonstrated that drugs interact differently with DC in drug allergic and non-allergic patients, but there are no studies regarding these subsets. Our aim was to assess the functional changes of mDC and pDC harvested from an amoxicillin-hypersensitive 32-year-old woman who experienced a severe maculopapular exanthema... Tipo: Info:eu-repo/semantics/other Palavras-chave: Dendritic cells; Β-lactam hypersensivity; Plasmacytoid dendritic cells; Drug allergy. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001000007 Registros recuperados: 2 Primeira ... 1 ... Última

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