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Food restriction beginning at lactation interferes with the cellular dynamics of the mucosa and colonic myenteric innervation in adult rats 42
SCHOFFEN,JOÃO PAULO F.; VICENTINI,FERNANDO A.; MARCELINO,CAROLINA G.; ARAÚJO,EDUARDO J.A.; PEDROSA,MARIA M.D.; NATALI,MARIA R.M..
The effects of food restriction (FR) on the morphoquantitative aspects of the wall and myenteric neurons of the proximal colon in adult rats were analysed. FR was imposed by duplication of the experimental brood size in relation to the control brood during lactation. The FR group received a 50% reduction of food from weaning until 90 days of age. Samples of the colon underwent histological processing to morphometrically analyze the crypts, muscularis mucosae, tunica mucosa, and muscularis externa. We determined the number of goblet cells and serotoninergic enteroendocrine cells, and morphoquantitatively studied the myenteric neuronal population. FR caused hypertrophy in the tunica mucosa, increase in crypt depth and in the muscular layer of the mucosa, a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Enteroendocrine cells; Food restriction; Goblet cells; Intestinal morphology; Myenteric neurons; Serotonin.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000401833
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