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| Registros recuperados: 33 | |
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| Cocca,Claudia; Ventura,Clara; Nunez,Mariel; Randi,Andrea; Venturino,Andres. |
| El clorpirifos (CPF) es un insecticida de amplio espectro que se utiliza en Argentina y en otros países de Latinoamérica. Se emplea para el control de plagas en la producción de frutas, hortalizas, cereales y plantas ornamentales. El principal mecanismo de acción descripto para este insecticida es la inhibición de la acetilcolinesterasa. Sin embargo, reportes más recientes sugieren múltiples efectos del plaguicida independientes de la inhibición de esa enzima. El objetivo de este trabajo es transmitir a la comunidad los resultados de nuestras investigaciones obtenidos utilizando diferentes dosis de CPF en distintos modelos experimentales, tanto in vitro como in vivo. En relación a esto, hemos evidenciado una acción del CPF sobre el sistema redox celular... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Clorpirifos; Cáncer de mama; Estradiol; ERO. |
| Ano: 2015 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432015000300005 |
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| Camargos,A.; Wohlres-Viana,S.; Costa,I.F.; Camargo,L.S.; Ferreira,J.C.; Ramos,A.A.; Oba,E.. |
| ABSTRACT The present study investigated the hormonal profile and expression of prostaglandin F2α (PGF2α), oxytocin and estrogen receptors in uterine tissues of postpartum cows treated with cloprostenol. Twenty Holstein-Zebu crossbred cows were treated with saline solution (treatment CONT) or cloprostenol (treatment CLO), both administered two and five days postpartum. Blood samples were collected on days two, seven, 14, 21 and 28 postpartum for progesterone, PGF2α metabolite (PGFM) and estradiol determination, and endometrial biopsy was performed in order to quantify the expression of oxytocin receptor (OXTR), prostaglandin F receptor (PTGFR) and estrogen receptor 1 (ERS1) genes. In the CLO treatment, expression of OXTR was reduced (P<0.05) but no... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: PTGFR; ESR1; Progesterone; Estradiol; RT-PCR. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000400821 |
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| Paz,R.C.R.; Souza,N.P.; Furtado,P.V.; Brown,J.L.. |
| ABSTRACT In this study, four crab-eating fox females (Cerdocyon thous) maintained at the Federal University of Mato Grosso Zoo, Cuiabá, Brazil, were investigated for 12 months, using feces measurement of estradiol and progesterone concentrations. Fecal collections were performed three times a week for hormone extraction. Two methods of analysis, Elisa (EIA) and Radioimmunoassay (RIA), were used in the measurement of progesterone (P4) and estradiol (E2) metabolites. The aim of this study was to compare and validate two different methods of hormone measurement for C. thous. There were no differences regarding the method used. The Radioimmunoassay technique proved to be more sensitive, however, both showed similar results. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Radioimmunoassay; Elisa; Estradiol; Progesterone; Fecal. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000300636 |
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| Santos,B.D.; Silva,M.C.G.; Santos,T.P.; Silva,S.C.B.L.; Cadena,M.R.S.; Cadena,P.G.. |
| Os hormônios esteroides presentes em várias gerações de contraceptivos orais combinados (COC) podem se apresentar como disruptores endócrinos, produzindo alterações no comportamento e na fisiologia de peixes. Diante disso, o objetivo deste trabalho foi avaliar os efeitos de hormônios esteroides presentes em COC sobre os parâmetros comportamentais de Betta splendens, um peixe ornamental usado na aquariofilia e bastante agressivo. Machos adultos foram observados pelo método ad libitum para confecção do etograma e divididos em cinco grupos, controle e expostos aos hormônios: 17β-estradiol (E2); levonorgestrel e etinilestradiol (LEA - segunda geração de COC); gestodeno e etinilestradiol (GEA - terceira geração de COC); e drospirenona e etinilestradiol (DEA -... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Betta splendens; Estradiol; Etinilestradiol; Etograma; Comportamento agressivo. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000200387 |
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| Da,Yun‑Meng; Niu,Kai‑Yu; Liu,Shu‑Ya; Wang,Ke; Wang,Wen‑Juan; Jia,Jing; Qin,Li‑Hua; Bai,Wen‑Pei. |
| Abstract Background Cimicifuga racemosa is one of the herbs used for the treatment of climacteric syndrome, and it has been cited as an alternative therapy to estrogen. Apart from hectic fevers, dyspareunia and so on, dry mouth also increase significantly after menopause. It has not yet been reported whether C. racemosa has any impact on the sublingual gland, which may relate to dry mouth. In an attempt to determine this, we have compared the effects of estrogen and C. racemosa on the sublingual gland of ovariectomized rats. Results HE staining showed that the acinar cell area had contracted and that the intercellular spaces were broadened in the OVX (ovariectomized rats) group, while treatment with estradiol (E2) and iCR (isopropanolic extract of C.... |
| Tipo: Journal article |
Palavras-chave: Estradiol; Cimicifuga racemosa; Sublingual gland; Subcellular structure; Caspase-3. |
| Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100209 |
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| PEÑARROJA-MATUTAN0,C; PARADA-BUSTAMANTE,A; ORIHUELA,P A; RÍOS,M; VELASQUEZ,LUIS A; CROXATTO,H B. |
| Estradiol (E2) accelerates oviductal egg transport through nongenomic pathways involving oviductal protein phosphorylation in non-mated rats, and through genomic pathways in mated rats. Here we investigated the ability of cervico-vaginal stimulation (CVS) to switch the mode of action of E2 in the absence of other male-associated components. Pro-estrous rats were subjected to CVS with a glass rod and 12 hours later were injected subcutaneously with E2 and intrabursally with the RNA synthesis inhibitor Actinomycin D or the protein phosphorylation inhibitor H-89. The number of eggs in the oviduct, assessed 24 h later, showed that Actinomycin D, but not H-89 blocked the E2-induced egg transport acceleration. This clearly indicates that CVS alone, without other... |
| Tipo: Journal article |
Palavras-chave: Mating; Oviduct; Estradiol; Signaling pathways; Prolactin receptor; Egg transport; Rat. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000200012 |
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| Pejic,S.; Kasapovic,J.; Cvetkovic,D.; Pajovic,S.B.. |
| The sensitivity of copper,zinc (CuZn)- and manganese (Mn)-superoxide dismutase (SOD) to exogenous estradiol benzoate (EB) was investigated in Wistar rats during postnatal brain development. Enzyme activities were measured in samples prepared from brains of rats of both sexes and various ages between 0 and 75 days, treated sc with 0.5 µg EB/100 g body weight in 0.1 ml olive oil/100 g body weight, 48 and 24 h before sacrifice. In females, EB treatment stimulated MnSOD activity on days 0 (66.1%), 8 (72.7%) and 15 (81.7%). In males, the stimulatory effect of EB on MnSOD activity on day 0 (113.6%) disappeared on day 8 and on days 15 and 45 it became inhibitory (40.3 and 30.5%, respectively). EB had no effect on the other age groups. The stimulatory effect of EB... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brain; Brain development; Estradiol; Superoxide dismutase. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000500004 |
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| Xu,B.L.; Zhao,Q.Z.; Gao,X.Y.; Hou,G.J.. |
| Sex hormones from environmental and physiological sources might play a major role in the pathogenesis of hepatoblastoma in children. This study investigated the effects of estradiol and bisphenol A on the proliferation and telomerase activity of human hepatoblastoma HepG2 cells. The cells were divided into 6 treatment groups: control, bisphenol A, estradiol, anti-estrogen ICI 182,780 (hereinafter ICI), bisphenol A+ICI, and estradiol+ICI. Cell proliferation was measured based on average absorbance using the Cell Counting-8 assay. The cell cycle distribution and apoptotic index were determined by flow cytometry. Telomerase activity was detected by polymerase chain reaction and a telomeric repeat amplification protocol assay. A higher cell density was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Estradiol; Bisphenol A; HepG2; Telomerase activity. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001101004 |
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| Araújo,J.M.D.; Silva,L.A.S.; Felix,F.B.; Camargo,E.A.; Grespan,R.. |
| Eosinophils are abundant in the reproductive tract, contributing to the remodeling and successful implantation of the embryo. However, the mechanisms by which eosinophils migrate into the uterus and their relationship to edema are still not entirely clear, since there are a variety of chemotactic factors that can cause migration of these cells. Therefore, to evaluate the role of CCR3 in eosinophil migration, ovariectomized C57BL/6 mice were treated with CCR3 antagonist SB 328437 and 17β-estradiol. The hypothesis that the CCR3 receptor plays an important role in eosinophil migration to the mouse uterus was confirmed, because we observed reduction in eosinophil peroxidase activity in these antagonist-treated uteruses. The antagonist also influenced uterine... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Estradiol; Chemokine receptor; Immunology; Menopause; Uterus. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000100603 |
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| Souza,M.F.; Couto-Pereira,N.S.; Freese,L.; Costa,P.A.; Caletti,G.; Bisognin,K.M.; Nin,M.S.; Gomez,R.; Barros,H.M.T.. |
| Cocaine sensitization is a marker for some facets of addiction, is greater in female rats, and may be influenced by their sex hormones. We compared the modulatory effects of endogenous or exogenous estradiol and progesterone on cocaine-induced behavioral sensitization in 106 female rats. Ovariectomized female rats received progesterone (0.5 mg/mL), estradiol (0.05 mg/mL), progesterone plus estradiol, or the oil vehicle. Sham-operated control females received oil. Control and acute subgroups received injections of saline, while the repeated group received cocaine (15 mg/kg, ip) for 8 days. After 10 days, the acute and repeated groups received a challenge dose of cocaine, after which locomotion and stereotypy were monitored. The estrous cycle phase was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cocaine; Locomotor activity; Female rats; Estradiol; Progesterone; Stereotypic activity. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000600505 |
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| Furlanetto,T.W.; Nunes Jr.,R.B.; Sopelsa,A.M.I.; Maciel,R.M.B.. |
| Estradiol has well-known indirect effects on the thyroid. A direct effect of estradiol on thyroid follicular cells, increasing cell growth and reducing the expression of the sodium-iodide symporter gene, has been recently reported. The aim of the present investigation was to study the effect of estradiol on iodide uptake by thyroid follicular cells, using FRTL-5 cells as a model. Estradiol decreased basal iodide uptake by FRTL-5 cells from control levels of 2.490 ± 0.370 to 2.085 ± 0.364 pmol I-/µg DNA at 1 ng/ml (P<0.02), to 1.970 ± 0.302 pmol I-/µg DNA at 10 ng/ml (P<0.003), and to 2.038 ± 0.389 pmol I-/µg DNA at 100 ng/ml (P<0.02). In addition, 4 ng/ml estradiol decreased iodide uptake induced by 0.02 mIU/ml thyrotropin from 8.678 ± 0.408 to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Iodide uptake; Estradiol; Thyroid; Follicular cells. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200015 |
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| Lisbôa,P.C.; Curty,F.H.; Moreira,R.M.; Pazos-Moura,C.C.. |
| There is little information on the possible effects of estrogen on the activity of 5'-deiodinase (5'-ID), an enzyme responsible for the generation of T3, the biologically active thyroid hormone. In the present study, anterior pituitary sonicates or hepatic and thyroid microsomes from ovariectomized (OVX) rats treated or not with estradiol benzoate (EB, 0.7 or 14 µg/100 g body weight, sc, for 10 days) were assayed for type I 5'-ID (5'-ID-I) and type II 5'-ID (5'-ID-II, only in pituitary) activities. The 5'-ID activity was evaluated by the release of 125I from deiodinated 125I rT3, using specific assay conditions for type I or type II. Serum TSH and free T3 and free T4 were measured by radioimmunoassay. OVX alone induced a reduction in pituitary 5'-ID-I... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 5'-iodothyronine deiodinase; Ovariectomy; Estradiol; Triiodothyronine; Thyroxine; Thyrotropin. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001200016 |
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| Silva,L.E.C.M.; Castro,M.; Amaral,F.C.; Antunes-Rodrigues,J.; Elias,L.L.K.. |
| Estradiol participates in the control of energy homeostasis, as demonstrated by an increase in food intake and in body weight gain after ovariectomy in rats. In the present study, female Wistar rats (200-230 g, N = 5-15 per group), with free access to chow, were individually housed in metabolic cages. We investigated food intake, body weight, plasma leptin levels, measured by specific radioimmunoassay, and the hypothalamic mRNA expression of orexigenic and anorexigenic neuropeptides, determined by real-time PCR, in ovariectomized rats with (OVX+E) and without (OVX) estradiol cypionate treatment (10 µg/kg body weight, sc, for 8 days). Hormonal and mRNA expression were determined at pre-feeding and 4 h after food intake. OVX+E rats showed lower food intake,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Estradiol; Leptin; Orexigenic and anorexigenic neuropeptides; Hypothalamus. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000800009 |
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| Teixeira,Lucia De Fátima Andrade Correia; Perez,Juan Ramon Olalquiaga; Ferreira,Daniel Furtado; Souza,José Camisão de; Muniz,Joel Augusto; Head,H. Herbert. |
| Foram avaliados os efeitos de dietas aniônicas (DA) e catiônicas (DC), associadas ou não ao uso de estradiol em dois períodos secos: período seco curto (30 dias) (PSC) e período seco regular (60 dias) (PSR) sobre o consumo de matéria seca (MS) de 40 vacas Holandesas, nos períodos pré-parto (PREP) e pós-parto (PP), distribuídas aleatoriamente em esquema fatorial 2x2+2. As dietas foram fornecidas por 21 dias no período pré-parto, após o qual, as vacas passaram a receber uma dieta de lactação. As DA não tiveram efeito sobre o consumo de MS no PREP; entretanto, resultaram em maior consumo quando comparadas à DC no pós-parto. Os contrastes entre tratamentos mostraram que DA fornecidas no PREP produziram aumento no consumo PP, PSR e no PSC associadas ao... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dietas aniônicas; Estradiol; Período seco curto. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542003000400024 |
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| Siqueira,Lucas Carvalho; Oliveira,João Francisco Coelho de; Loguércio,Rosane da Silveira; Löf,Henrique Kurtz; Gonçalves,Paulo Bayard Dias. |
| O objetivo do presente experimento foi investigar se a realização exclusiva da inseminação artificial em tempo fixo (IATF), empregando como indutor da ovulação o benzoato de estradiol (BE), proporciona taxas de prenhez semelhantes a uma associação de IA convencional e IATF com GnRH, em vacas de corte no pós-parto. Duzentos e cinqüenta vacas amamentado receberam um pessário vaginal contendo 250mg de acetato de medroxi-progesterona (MAP) e uma injeção intramuscular (IM) de 5mg de BE no dia 0. O pessário vaginal permaneceu por sete dias. No dia 6, foram aplicadas 400UI de gonadotrofina coriônica eqüina por via IM e 5mg de análogo de prostaglandina na submucosa vulvar, realizando nesse momento o desmame por 96h. Após a retirada dos pessários (dia 7), as vacas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pós-parto; IATF; Indução de estro; GnRH; Estradiol. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782008000200019 |
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| Registros recuperados: 33 | |
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