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Morphological and Morphometric Study of the Muscle Fibers and Neuromuscular Junctions of the Extensor Digitorum Longus in Aged Rats Submitted to Maternal Protein Restriction International Journal of Morphology
Jeronimo,L. C; Confortim,H. D; Centenaro,L. A; Brancalhão,R. M. C; Pinheiro,P. F. F; Matheus,S. M. M; Torrejais,M. M.
Protein restriction implies the functional involvement of several systems and organs, including the skeletal muscle, because it is a protein reservoir in the body. This study sought to analyze the morphological and morphometric features of the muscle fibers and neuromuscular junctions (NMJs) of the extensor digitorum longus (EDL) muscle in rats at 365 days of age, submitted to maternal protein restriction during the gestation and lactation periods. Wistar rats were divided into two groups: a Control Group - mothers fed a normal-protein diet (17 % protein) during pregnancy and lactation; and a Restricted Group - mothers fed a low-protein diet (6 % protein) during pregnancy and lactation. The pups were kept with the mother throughout the lactation period (21...
Tipo: Journal article Palavras-chave: Morphology; Morphometry; Protein restriction; Extensor digitorum longus muscle; Rat.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100057
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Ultrastructural Study of the Neuromuscular Junctions of Extensor Digitorum Longus Muscle (M. extensor digitorum longus) of the Mice International Journal of Morphology
Boaro,Sueli N; Fragoso Neto,Raul A.
The neuromuscular junction of the extensor digitorum longus muscle of fingers was analyzed in 21 young (three months) and old (from six to 25 months) mice, from both genders. Morphologic changes were found throughout the mouse life, being more frequent and visible with aging. According with the data described in the literature consulted and the observations taken in this research, it becomes clear that a continuous process of morphological remodeling occurs in all neuromuscular ultrastructural junctions of the extensor digitorum longus muscle of fingers, during the life of the animal. Theses changes are characterized by figures of myelin in the cytoplasm of Schwann cells, pleomorphic and multivesiclar bodies, mitochondrias with morphologically altered...
Tipo: Journal article Palavras-chave: Neuromuscular junctions; Mice; Ultrastructure; Extensor digitorum longus muscle.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300045
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