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	Provedor de dados Anais da ABC (AABC) (1) Autor HOLTHOFF,KNUT (1) NIERMANN,HEIKE (1) WITTE,OTTO W. (1) Palavra-chave Brain slice (1) Extracellular space volume (1) Intrinsic optic signals (1) Spatial buffer (1) Spreading depression (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2001 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Cell swelling and ion redistribution assessed with intrinsic optical signals Anais da ABC (AABC) WITTE,OTTO W.; NIERMANN,HEIKE; HOLTHOFF,KNUT. Cell volume changes are associated with alterations of intrinsic optical signals (IOS). In submerged brain slices in vitro, afferent stimulation induces an increase in light transmission. As assessed by measurement of the largely membrane impermeant ion tetramethylammonium (TMA) in the extracellular space, these IOS correlate with the extent and time course of the change of the extracellular space size. They have a high signal to noise ratio and allow measurements of IOS changes in the order of a few percent. Under conditions of reduced net KCl uptake (low Cl solution) a directed spatial buffer mechanism (K syphoning) can be demonstrated in the neocortex with widening of the extracellular space in superficial layers associated with a reduced light... Tipo: Info:eu-repo/semantics/article Palavras-chave: Intrinsic optic signals; Spatial buffer; Brain slice; Extracellular space volume; Spreading depression. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000300005 Registros recuperados: 1 Primeira ... 1 ... Última

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