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The use of snake venom derived fibrin glue in hysterorrhaphy of ovine caesarean surgery J. Venom. Anim. Toxins
CHALHOUB,M.; PRESTES,N. C.; LOPES,M. D.; ROCHA,N. S.; THOMAZINI-SANTOS,I. A.; MENDES-GIANNINI,M.J..
Fibrin glue has been used on its own or in conjunction with suturing materials to promote hemostasis, reduce adherence, strengthen the wound site, and improve healing. Snake venom derived fibrin glue was evaluated as an alternative to conventional uterine suturing after ovine caesarean surgery. Twenty-eight pregnant ewes of known mating date were used. The animals submitted to conventional caesarean sections showed a better wound healing process. As expected, all the operated animals had retained placenta, compromising coaptation of wound edges. This had a strong influence in the results observed with the animals in which fibrin glue was used. The animals were divided into four groups GI, GII, GIII, and GIV and sacrificed, respectively, 3, 7, 15, and 30...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fibrin tissue adhesive; Viper venoms; Uterus/sutures; Sheep; Fibrin glue.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200007
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Multiple uses of fibrin sealant for nervous system treatment following injury and disease J. Venom. Anim. Toxins incl. Trop. Dis.
Biscola,Natalia Perussi; Cartarozzi,Luciana Politti; Ulian-Benitez,Suzana; Barbizan,Roberta; Castro,Mateus Vidigal; Spejo,Aline Barroso; Ferreira Jr.,Rui Seabra; Barraviera,Benedito; Oliveira,Alexandre Leite Rodrigues.
Abstract Lesions to the nervous system often produce hemorrhage and tissue loss that are difficult, if not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place, expanding the lesion epicenter. This significantly worsens the patient conditions and impairment, increasing neuronal loss and glial reaction, which in turn further decreases the chances of a positive outcome. The possibility of using hemostatic substances that also function as a scaffold, such as the fibrin sealant, reduces surgical time and improve postoperative recovery. To date, several studies have demonstrated that human blood derived fibrin sealant produces positive effects in different interventions, becoming an efficient alternative to suturing. To...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Central nervous system; Peripheral nervous system; Commercial fibrin sealant; New heterologous fibrin sealant; Nervous system injury; Fibrin tissue adhesive.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100202
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