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Grégio,Juliana M.; Caetano,Marco A.L.; Yoneyama,Takashi. |
Optimal control theory provides a very interesting quantitative method that can be used to assist the decision making process in several areas of application, such as engineering, biology, economics and sociology. The main idea is to determine the values of the manipulated variables, such as drug doses, so that some cost function is minimized, subject to physical constraints. In this work, the cost function reflects the number of CD4+T cells, viral particles and the drug doses. It is worth noticing that high drug doses are related to more intense side-effects, apart from the impact on the actual cost of the treatment. In a previous paper by the authors, the LQR - Linear Quadratic Regulator approach was proposed for the computation of long period... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: AIDS; Filtering; Drugs; Mathematical modeling; Optimization. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000100002 |
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Duarte,Felipe Cimino; Cardoso,Maria das Graças; Pinheiro,Ana Carla Marques; Santiago,Wilder Douglas; Carvalho,Leonardo Luna de. |
Sugarcane spirit is a drink considered as a national symbol of Brazil. It is produced by large producers and by about 30 thousand small and medium home-distilling producers dispersed throughout the country. The copper originating from the home-distillers can become a serious problem since at high concentrations in beverages it may cause serious human health problems. Therefore, the objective of this study was to investigate the influence of the activated carbon used in commercial filters on the physicochemical and sensory characteristics of aged sugarcane spirit. Analyses of copper, dry extract, alcoholic degree, higher alcohols, volatile acids, aldehydes, esters, furfural, and methanol were performed. The sensory evaluation was performed by seven selected... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sugarcane spirit; Filtering; Carbon; Sensory and physicochemical analysis. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612012000300008 |
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