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Base de datos para factores de transcripción de Glycine max, Triticum aestivum y Zea maiz. Colegio de Postgraduados
Ramírez Sánchez, Obed.
Los factores de transcripción (FTs) son proteínas que incrementan o disminuyen la tasa transcripcional de uno o varios genes. Los FTs desempeñan un papel fundamental en el control de casi todos los procesos biológicos: crecimiento, metabolismo, respuesta a factores ambientales, etc. En plantas cultivadas, son de particular importancia aquellos relacionados con la respuesta al estrés (sequía, salinidad, bajas temperaturas, plagas, enfermedades, etc.). La identificación de FTs, su posterior anotación y la construcción de bases de datos públicas constituye un importante recurso para el estudio de los procesos que controlan la expresión génica. Se construyó la base de datos FT-MTS que contiene información de 13,975 genes identificados como FTs en los genomas...
Palavras-chave: Regulación transcripcional; Anotación funcional; Bioinformática; Transcriptional regulation; Functional annotation; Bioinformatics; Cómputo aplicado; Maestría.
Ano: 2012 URL: http://hdl.handle.net/10521/689
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Identification and validation of novel EST-SSR markers in olives Scientia Agricola
Arbeiter,Alenka Baruca; Hladnik,Matjaž; Jakše,Jernej; Bandelj,Dunja.
ABSTRACT: The olive (Olea europaea L.) is a leading oil crop in the Mediterranean area. Limited information on the inheritance of agronomic significant traits hinders progress in olive breeding programs, which encourages the development of markers linked to the traits. In this study, we report on the development of 46 olive simple sequence repeat (SSR) markers, obtained from 577,025 expressed sequence tags (ESTs) in developing olive fruits generated in the framework of the Slovenian national olive transcriptome project. Sequences were de novo assembled into 98,924 unigenes, which were then used as a source for microsatellites searching. We identified 923 unigenes that contained 984 SSRs among which dinucleotide SSRs (36 %) were the most abundant, followed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Expressed sequence tags; Microsatellites; Genic markers; Genetic diversity; Functional annotation.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162017000300215
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Identification of novel gene and pathway targets for human epilepsy treatment Biol. Res.
Jin,Ying; Zhao,Chunzhe; Chen,Lihui; Liu,Xiangyu; Pan,Shuxiao; Ju,Dongsheng; Ma,Jing; Li,Jinying; Wei,Bo.
BACKGROUND: The aim of this study was to explore epilepsy-related mechanism so as to figure out the possible targets for epilepsy treatment. METHODS: The gene expression profile dataset GES32534 was downloaded from Gene Expression Omnibus database. We identified the differentially expressed genes (DEGs) by Affy package. Then the DEGs were used to perform gene ontology (GO) and pathway enrichment analyses. Furthermore, a protein-protein interaction (PPI) network was constructed with the DEGs followed by co-expression modules construction and analysis. RESULTS: Total 420 DEGs were screened out, including 214 up-regulated and 206 down-regulated genes. Functional enrichment analysis revealed that down-regulated genes were mainly involved in the process of...
Tipo: Journal article Palavras-chave: Epilepsy; Differentially expressed genes; Functional annotation; Protein-protein interaction network; Co-expression module.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100003
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