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| Pardini,V.C.; Mourão,D.M.; Nascimento,P.D.; Vívolo,M.A.; Ferreira,S.R.G.; Pardini,H.. |
| Type 1 diabetes, as an autoimmune disease, presents several islet cell-specific autoantibodies such as islet cell antibody (ICA), anti-insulin, anti-glutamic acid decarboxylase (GAD) and the antibody (Ab) against tyrosine phosphatase (PTP)-like protein known as ICA-512 (IA-2). In order to determine the frequency of the anti-GAD and anti-IA-2 autoantibodies in Brazilian type 1 diabetes patients we studied 35 diabetes mellitus (DM) type 1 patients with recent-onset disease (<FONT FACE="Symbol">£</font>12 months) and 37 type 1 diabetes patients with long-duration diabetes (>12 months) who were compared to 12 children with normal fasting glucose. Anti-GAD65 and anti-IA-2 autoantibodies were detected with commercial immunoprecipitation... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Type 1 diabetes; Autoimmunity; GAD and IA-2 autoantibodies. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001000003 |
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