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Graça,J.R.V.; Leal,P.R.L.; Gondim,F.A.A.; Rola,F.H.; Santos,A.A.. |
The impact of acute volume imbalances on gastric volume (GV) was studied in anesthetized rats (250-300 g). After cervical and femoral vessel cannulation, a balloon catheter was positioned in the proximal stomach. The opposite end of the catheter was connected to a barostat with an electronic sensor coupled to a plethysmometer. A standard ionic solution was used to fill the balloon (about 3.0 ml) and the communicating vessel system, and to raise the reservoir liquid level 4 cm above the animals' xiphoid appendix. Due to constant barostat pressure, GV values were considered to represent the gastric compliance index. All animals were monitored for 90 min. After a basal interval, they were randomly assigned to normovolemic, hypervolemic, hypovolemic or... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Blood volume; Gastric compliance; Gastrointestinal motility; Hemorrhage; Hypervolemia. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000300018 |
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Bellomo-Brandão,M.A.; Collares,E.F.; da-Costa-Pinto,E.A.L.. |
The efficacy of erythromycin was assessed in the treatment of 14 children aged 4 to 13 years with refractory chronic constipation, and presenting megarectum and fecal impaction. A double-blind, placebo- controlled, crossover study was conducted at the Pediatric Gastroenterology Outpatient Clinic of the University Hospital. The patients were randomized to receive placebo for 4 weeks followed by erythromycin estolate, 20 mg kg-1 day-1, divided into four oral doses for another 4 weeks, or vice versa. Patient outcome was assessed according to a clinical score from 12 (most severe clinical condition) to 0 (complete recovery). At enrollment in the study and on the occasion of follow-up medical visits at two-week intervals, patient score and laxative requirements... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Gastrointestinal motility; Constipation; Children; Prokinetics; Erythromycin. |
Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000016 |
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de-Oliveira,G.R.; Gondim,F. de-A.A.; da-Graça,J.R.V.; Xavier-Neto,J.; Dantas,R.P.; Gondim,R.B.M.; Santos,A.A.; Rola,F.H.. |
The present study evaluates the effect of blood volume expansion on the gastrointestinal transit of a charchoal meal (2.5 ml of an aqueous suspension consisting of 5% charcoal and 5% gum arabic) in awake male Wistar rats (200-270 g). On the day before the experiments, the rats were anesthetized with ether, submitted to left jugular vein cannulation and fasted with water ad libitum until 2 h before the gastrointestinal transit measurement. Blood volume expansion by iv infusion of 1 ml/min Ringer bicarbonate in volumes of 3, 4 or 5% body weight delayed gastrointestinal transit at 10 min after test meal administration by 21.3-26.7% (P<0.05), but no effect was observed after 1 or 2% body weight expansion. The effect of blood volume expansion (up to 5%... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hypervolemia; Blood volume; Gastrointestinal transit; Rats; Gastrointestinal motility. |
Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000600017 |
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Gondim,F. de-A.A.; Oliveira,G.R. de-; Graça,J.R.V.; Cavalcante,D.I.M.; Souza,M.A.N.; Santos,A.A.; Rola,F.H.. |
We have observed that acute blood volume expansion increases the gastroduodenal resistance to the flow of liquid in anesthetized dogs, while retraction decreases it (Santos et al. (1991) Acta Physiologica Scandinavica, 143: 261-269). This study evaluates the effect of blood volume expansion and retraction on the gastric emptying of liquid in awake rats using a modification of the technique of Scarpignato (1980) (Archives Internationales de Pharmacodynamie et de Therapie, 246: 286-294). Male Wistar rats (180-200 g) were fasted for 16 h with water ad libitum and 1.5 ml of the test meal (0.5 mg/ml phenol red solution in 5% glucose) was delivered to the stomach immediately after random submission to one of the following protocols: 1) normovolemic control (N =... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Blood volume; Hypervolemia; Hemorrhage; Central venous pressure; Gastric emptying; Gastrointestinal motility. |
Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000700013 |
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