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Quantitative genetics theory for genomic selection and efficiency of genotypic value prediction in open-pollinated populations Scientia Agricola
Viana,José Marcelo Soriano; Piepho,Hans-Peter; Silva,Fabyano Fonseca e.
ABSTRACT: Quantitative genetics theory for genomic selection has mainly focused on additive effects. This study presents quantitative genetics theory applied to genomic selection aiming to prove that prediction of genotypic value based on thousands of single nucleotide polymorphisms (SNPs) depends on linkage disequilibrium (LD) between markers and QTLs, assuming dominance and epistasis. Based on simulated data, we provided information on dominance and genotypic value prediction accuracy, assuming mass selection in an open-pollinated population, all quantitative trait loci (QTLs) of lower effect, and reduced sample size. We show that the predictor of dominance value is proportional to the square of the LD value and to the dominance deviation for each QTL...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Genome-wide selection; Dominance value prediction; Prediction accuracy.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162017000100041
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Quantitative genetics theory for genomic selection and efficiency of breeding value prediction in open-pollinated populations Scientia Agricola
Viana,José Marcelo Soriano; Piepho,Hans-Peter; Silva,Fabyano Fonseca e.
ABSTRACT To date, the quantitative genetics theory for genomic selection has focused mainly on the relationship between marker and additive variances assuming one marker and one quantitative trait locus (QTL). This study extends the quantitative genetics theory to genomic selection in order to prove that prediction of breeding values based on thousands of single nucleotide polymorphisms (SNPs) depends on linkage disequilibrium (LD) between markers and QTLs, assuming dominance. We also assessed the efficiency of genomic selection in relation to phenotypic selection, assuming mass selection in an open-pollinated population, all QTLs of lower effect, and reduced sample size, based on simulated data. We show that the average effect of a SNP substitution is...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Genome-wide selection; Additive value prediction; Prediction accuracy.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162016000300243
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