Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BABT (1) BJPS (1) Autor Asad,Muhammad (1) Bashir,Sajid (1) Gaikwad,Naresh Janardan (1) Imran,Muhammad (1) Karim,Sabiha (1) Mahmood,Tariq (1) Nazir,Imran (1) Patil,Moreshwar Pandharinath (1) ul Hassnain,Fakhar (1) Mais... Palavra-chave Gliclazide (2) Guar gum (1) In vitro dissolution (1) Ionotropic-gelation method (1) Microcapsules (1) Pectin (1) Polyethylene glycol 6000 (1) Solid dispersion (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2014 (1) 2011 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Fabrication and Characterization of Gliclazide Loaded Microcapsules BABT Asad,Muhammad; Bashir,Sajid; Mahmood,Tariq; Nazir,Imran; Imran,Muhammad; Karim,Sabiha; ul Hassnain,Fakhar. This study aimed to formulate, characterize and evaluate the Gliclazide (GLZ) microcapsules prepared with sodium alginate, guar gum and pectin in different ratios by ionotropic-gelation method. The microcapsules were evaluated against different parameters such as particle size and shape, Carr's index, Hausner's ratio, rheological studies and drug release kinetics. Fourier Transform Infra Red (FTIR) and Differential Scanning Calorimetric (DSC) studies demonstrated the absence of any drug - polymers interaction. Promising characteristics were observed in rheological behavior and release kinetics. The size of microcapsules and percentage yield was in the range of 676 to 727 µm and 69 to 77%, respectively. Scanning electron micrographs revealed that... Tipo: Info:eu-repo/semantics/article Palavras-chave: Microcapsules; Gliclazide; Ionotropic-gelation method; Guar gum; Pectin. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000600874 Characterization of gliclazide-polyethylene glycol solid dispersion and its effect on dissolution BJPS Patil,Moreshwar Pandharinath; Gaikwad,Naresh Janardan. The present study was initiated with the objective of studying the in vitro dissolution behavior of gliclazide from its solid dispersion with polyethylene glycol 6000. In this work, a solid dispersion of gliclazide with polyethylene glycol was prepared by the fusion method. In vitro dissolution study of gliclazide, its physical mixture and solid dispersion were carried out to demonstrate the effect of PEG 6000. Analytical techniques of FT-IR spectroscopy, differential scanning calorimetry and X-ray diffractometry were used to characterize the drug in the physical mixtures and solid dispersions. The dissolution studies of solid dispersion and physical mixture showed greater improvement compared to that of the pure drug. The mechanisms for increased... Tipo: Info:eu-repo/semantics/article Palavras-chave: Gliclazide; Polyethylene glycol 6000; Solid dispersion; In vitro dissolution. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000100020 Registros recuperados: 2 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco