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	Provedor de dados BJMBR (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Handford,M. (1) Orellana,A. (1) Rodriguez-Furlán,C. (1) Sampaio,Suely V. (1) Sartim,Marco A. (1) Palavra-chave Glycoconjugates (2) Antitumor activity (1) Bactericidal activity (1) C-type lectin (1) Carbohydrate recognition domain (1) Galactoside-binding protein (1) Glycosyltransferases (1) Golgi apparatus (1) Inflammatory response (1) Mitogenic activity (1) Nucleotide-sugar transporters (1) Nucleotide-sugars (1) Platelet aggregation (1) Snake venom (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2015 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Nucleotide-sugar transporters: structure, function and roles in vivo BJMBR Handford,M.; Rodriguez-Furlán,C.; Orellana,A.. The glycosylation of glycoconjugates and the biosynthesis of polysaccharides depend on nucleotide-sugars which are the substrates for glycosyltransferases. A large proportion of these enzymes are located within the lumen of the Golgi apparatus as well as the endoplasmic reticulum, while many of the nucleotide-sugars are synthesized in the cytosol. Thus, nucleotide-sugars are translocated from the cytosol to the lumen of the Golgi apparatus and endoplasmic reticulum by multiple spanning domain proteins known as nucleotide-sugar transporters (NSTs). These proteins were first identified biochemically and some of them were cloned by complementation of mutants. Genome and expressed sequence tag sequencing allowed the identification of a number of sequences that... Tipo: Info:eu-repo/semantics/other Palavras-chave: Glycoconjugates; Glycosyltransferases; Golgi apparatus; Nucleotide-sugars; Nucleotide-sugar transporters. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000900002 Snake venom galactoside-binding lectins: a structural and functional overview J. Venom. Anim. Toxins incl. Trop. Dis. Sartim,Marco A.; Sampaio,Suely V.. AbstractSnake venom galactoside-binding lectins (SVgalLs) comprise a class of toxins capable of recognizing and interacting with terminal galactoside residues of glycans. In the past 35 years, since the first report on the purification of thrombolectin from Bothrops atrox snake venom, several SVgalLs from Viperidae and Elapidae snake families have been described, as has progressive improvement in the investigation of structural/functional aspects of these lectins. Moreover, the advances of techniques applied in protein-carbohydrate recognition have provided important approaches in order to screen for possible biological targets. The present review describes the efforts over the past 35 years to elucidate SVgalLs, highlighting their structure and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Snake venom; C-type lectin; Galactoside-binding protein; Carbohydrate recognition domain; Glycoconjugates; Inflammatory response; Antitumor activity; Bactericidal activity; Mitogenic activity; Platelet aggregation. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100213 Registros recuperados: 2 Primeira ... 1 ... Última

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