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Effect of Gestational Diabetes on Neuronal Cells in Rat Cerebellum in Early Postnatal Life International Journal of Morphology
Razi,Elahe Mirarab; Ghafari,Soraya; Hojati,Vida; Golalipour,Mohammad Jafar.
Previous study has shown the adverse effects of gestational diabetes on hippocampal neuronal density in animal model. This study was conducted to determine the effect of gestational diabetes on rat cerebellum in early postnatal life. In this experimental study, 10 dams randomly allocated into control and diabetic groups on day 1 of gestation. Five dams in diabetic group were administered 40 mg/kg/BW (intraperitoneally) of streptozotocin and control animals received normal saline. Six offspring of each gestational diabetes mellitus and controls were randomly selected at day 7 of postnatal life. Offspring were sacrificed and coronal sections were taken from the cerebellum and stained with cresyl violet. The number of Purkinje and granular cells and thickness...
Tipo: Journal article Palavras-chave: Gestational diabetes; Cerebellum; Purkinje cell; Granular cell; Rat.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000200006
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