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	Provedor de dados BJMBR (3) Autor Antunes-Rodrigues,J. (1) Fonteles,M.C. (1) Gutkowska,J. (1) Lima,A.A.M. (1) McCann,S.M. (1) Murad,F. (1) Mais... Palavra-chave Guanylyl cyclase (3) Nitric oxide (2) Angiotensin II (1) Atrial natriuretic peptide (1) Cell signaling (1) Electrolyte and water balance (1) Guanylin (1) Heat-stable enterotoxin (1) Kidney function (1) Nitric oxide synthase (1) Oxytocin (1) Secretory diarrhea (1) Vasopressin (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2014 (1) 2003 (1) 1999 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Cellular signaling with nitric oxide and cyclic GMP BJMBR Murad,F.. During the past two decades, nitric oxide signaling has been one of the most rapidly growing areas in biology. This simple free radical gas can regulate an ever growing list of biological processes. In most instances nitric oxide mediates its biological effects by activating guanylyl cyclase and increasing cyclic GMP synthesis. However, the identification of effects of nitric oxide that are independent of cyclic GMP is also growing at a rapid rate. The effects of nitric oxide can mediate important physiological regulatory events in cell regulation, cell-cell communication and signaling. Nitric oxide can function as an intracellular messenger, neurotransmitter and hormone. However, as with any messenger molecule, there can be too much or too little of the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nitric oxide; Nitric oxide synthase; Guanylyl cyclase; Cell signaling. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001100001 From Escherichia coli heat-stable enterotoxin to mammalian endogenous guanylin hormones BJMBR Lima,A.A.M.; Fonteles,M.C.. The isolation of heat-stable enterotoxin (STa) from Escherichia coli and cholera toxin from Vibrio cholerae has increased our knowledge of specific mechanisms of action that could be used as pharmacological tools to understand the guanylyl cyclase-C and the adenylyl cyclase enzymatic systems. These discoveries have also been instrumental in increasing our understanding of the basic mechanisms that control the electrolyte and water balance in the gut, kidney, and urinary tracts under normal conditions and in disease. Herein, we review the evolution of genes of the guanylin family and STa genes from bacteria to fish and mammals. We also describe new developments and perspectives regarding these novel bacterial compounds and peptide hormones that act in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Heat-stable enterotoxin; Guanylin; Guanylyl cyclase; Secretory diarrhea; Kidney function; Electrolyte and water balance. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000300179 Neuroendocrine control of body fluid homeostasis BJMBR McCann,S.M.; Gutkowska,J.; Antunes-Rodrigues,J.. Angiotensin II and atrial natriuretic peptide (ANP) play important and opposite roles in the control of water and salt intake, with angiotensin II promoting the intake of both and ANP inhibiting the intake of both. Following blood volume expansion, baroreceptor input to the brainstem induces the release of ANP within the hypothalamus that releases oxytocin (OT) that acts on its receptors in the heart to cause the release of ANP. ANP activates guanylyl cyclase that converts guanosine triphosphate into cyclic guanosine monophosphate (cGMP). cGMP activates protein kinase G that reduces heart rate and force of contraction, decreasing cardiac output. ANP acts similarly to induce vasodilation. The intrinsic OT system in the heart and vascular system augments the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Oxytocin; Vasopressin; Atrial natriuretic peptide; Nitric oxide; Angiotensin II; Guanylyl cyclase. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000200003 Registros recuperados: 3 Primeira ... 1 ... Última

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