|
|
| Eloy,Alba Maria Xavier; Moreira,Regina Célia; Lemos,Marcílio Figueiredo; Silva,Jéfferson Luis de Almeida; Coêlho,Maria Rosângela Cunha Duarte. |
| The aims of this study were to investigate the genotypes of hepatitis B virus and to identify the precore G1896A and basal core promoter A1762T/G1764A mutations in HBsAg and anti-HBc-positive patients. Eighty-three asymptomatic individuals, three with acute hepatitis B and 33 with chronic hepatitis B referred to viral hepatitis centers in the State of Alagoas, Brazil were analyzed according to their viral load, HBeAg/anti-HBe profile and alanine aminotransferase serum level. The genotypes identified were: A (92.5%), C (5%), D (1.25%) and F (1.25%). The precore mutation was detected in 3.8% of sequences and basal core promoter mutation in 52.4%. These were identified in 45.45% of the asymptomatic individuals and 54.55% of the patients with chronic... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Genotypes; HBV mutation; Alagoas; Brazil. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000600013 |
| |
