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| Vasconcellos,Isabelle; Mariani,Diana; Azevedo,Marcelo C.V.M. de; Ferreira Jr.,Orlando C.; Tanuri,Amilcar. |
| ABSTRACT A new point-of-care HIV viral load, mPIMA HIV-1/2 VL, Abbott, USA, has been recently developed. This point-of-care viral load requires no skilled person to run and uses a small plasma volume (50 µL). However, obtaining 50 µL of plasma can be a challenge in limited resource settings. We validated a simple and easy method to obtain enough amount of plasma to run a point-of-care viral load. The study utilized 149 specimens from patients failing antiretroviral therapy. At least 250 µL of whole blood was collected in a microtube/EDTA from fingerstick (fs-plasma) and immediately centrifuged. Parallel collection of venous blood to obtain plasma (vp-plasma) was used to compare performance in a point-of-care viral load assay and in methodology used in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: POC VL; HIV viral load; HIV; Point-of-care; Fingerstick-plasma; MPIMA. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000100030 |
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| Manfredi,Roberto; Sabbatani,Sergio; Calza,Leonardo. |
| A patient with HIV infection developed the first episode of AIDS-defining opportunism (severe Candida albicans esophagitis) with an underlying CD4+ lymphocyte count of 1,025 cells/µL. After treatment with a highly active antiretroviral therapy (HAART), taken with insufficient compliance and leaving a residual viral load, our patient suffered from two relapses of esophageal candidiasis, which occurred three months and seven years later, when his CD4+ lymphocyte count was 930 and 439 cells/µL, respectively, and a viral load slightly above 10(4) copies/mL was still present. Also in the HAART era, Candida esophagitis remains one of the most common AIDS-defining diseases, but a presentation with a concurrent CD4+ count above 1,000 cells/µL remains a rare... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Esophageal candidiasis; HIV infection; CD4+ lymphocyte count; HIV viral load; Recurring opportunistic disease; Antiretroviral therapy; Negligible or absent immunodeficiency. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000600016 |
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