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	Provedor de dados 55 (1) 56 (1) Autor Accetturi,C.A. (1) Brindeiro,Rodrigo (1) Carvalho,Denise Siqueira de (1) Caseiro,M. (1) Diaz,R.S. (1) Queiroz-Telles,Flávio de (1) Rossi,Silvia Gomes de (1) Rossini,M.A.A. (1) Sabino,E.C. (1) Toledo,Paula Virginia Michelon (1) Turcato,G. (1) Mais... Palavra-chave HIV-1 subtypes (2) Antiretroviral (1) Brazil (1) Drug experienced patients (1) Genotype (1) Heteroduplex mobility analysis (1) Intravenous drug users (1) Molecular epidemiology (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2010 (1) 2001 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Genetic diversity of human immunodeficiency virus-1 isolates in Paraná, Brazil 55 Toledo,Paula Virginia Michelon; Carvalho,Denise Siqueira de; Rossi,Silvia Gomes de; Brindeiro,Rodrigo; Queiroz-Telles,Flávio de. OBJECTIVE: Because epidemiological data on circulating HIV subtypes among HIV-positive patients in the state of Paraná were not known until now, the aims of this study were to describe the genetic diversity profile of HIV-1 in treated patients in Paraná, Brazil, and report the differences in protease (PR) and reverse transcriptase (RT) mutations in HIV-1 subtypes. PATIENTS AND METHODS: A cross-sectional study was conducted from 2003 to 2006. Plasma viral RNA of 389 patients was extracted and PR and RT genes were polymerase chain reaction-amplified and sequenced. Sequences were subtyped and examined for antiretroviral resistance mutations. Data on gender of patient harboring the viruses and past history of antiretroviral treatment were also collected.... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV-1 subtypes; Genotype; Antiretroviral; Drug experienced patients. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300006 HIV-1 subtypes among intravenous drug users from two neighboring cities in São Paulo State, Brazil 56 Rossini,M.A.A.; Diaz,R.S.; Caseiro,M.; Turcato,G.; Accetturi,C.A.; Sabino,E.C.. In order to assess the molecular epidemiology of HIV-1 in two neighboring cities located near the epicenter of the HIV-1 epidemics in Brazil (Santos and São Paulo), we investigated 83 HIV-1 strains obtained from samples collected in 1995 from intravenous drug users. The V3 through V5 region of the envelope of gp 120 was analyzed by heteroduplex mobility analysis. Of the 95 samples, 12 (12.6%) were PCR negative (6 samples from each group); low DNA concentration was the reason for non-amplification in half of these cases. Of the 42 typed cases from São Paulo, 34 (81%, 95% confidence limits 74.9 to 87.0%) were B and 8 (19%, 95% confidence limits 12.9 to 25.0%) were F, whereas of the 41 typed cases from Santos, 39 (95%, 95% confidence limits 91.6 to 98.4%)... Tipo: Info:eu-repo/semantics/other Palavras-chave: HIV-1 subtypes; Intravenous drug users; Molecular epidemiology; Heteroduplex mobility analysis; Brazil. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000100005 Registros recuperados: 2 Primeira ... 1 ... Última

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