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The environmental cofactors in carcinogenesis in high risk HPV/HIV-positive women BJID
Paulo,Michele; Borges,Alex Bittencourt; Duarte,Geraldo; Quintana,Silvana Maria; Montes,Marlise Bonetti Agostinho; Toloi,Maria Regina Torqueti.
The objective of the present study was to assess the presence of human papilloma virus (HPV) in HIV-infected women, with comparison between the Papanicolaou cytologic technique and the molecular PCR technique, as well as to determine the type of HPV, to measure cellular immunocompetence and to identify the presence of risk factors for the acquisition of HPV infection. Thirty HIV-infected women were selected. Vaginal and endocervical samples were collected from 27 of them. The smears were examined by 3 experienced cytologists to diagnose the presence of HPV by the Papanicolaou technique and the results were compared to HPV detection and typing by PCR. HPV-infected patients were interviewed in order to identify the presence of risk factors for the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HPV; HIV-infected women; Cervical cancer; Carcinogenesis; Antiretroviral therapy.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200003
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Human Papillomavirus prevalence, viral load and cervical intraepithelial neoplasia in HIV-infected women BJID
Levi,José E.; Fink,Maria C.S.; Canto,Cynthia L.M.; Carretiero,Nadily; Matsubara,Regina; Linhares,Iara; Dores,Gérson B. das; Castelo,Adauto; Segurado,Aluísio; Uip,David E.; Eluf Neto,José.
HIV-infected women from São Paulo city were enrolled in a cross-sectional study on Human Papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) prevalence and their association with laboratory markers of AIDS, namely HIV viral load and CD4+ cell counts. A cervical specimen was collected and submitted to Hybrid Capture, a test for HPV viral load determination. HPV-DNA was detected in 173 of 265 women (64.5%). Twenty (7.5%) women were infected by one or more low-risk viruses, 89 (33%) by one or more high-risk viruses, and 64 (24%) harbored at least one HPV type from each risk group. Abnormal smears were observed in 19% of the patients, though there were no invasive carcinomas. Severely immunosuppressed patients (CD4/µL <100) were at the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Human Papillomavirus; Cervical intraepithelial neoplasia; HIV-infected women; Viral load; AIDS.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000300005
Registros recuperados: 2
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