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	Provedor de dados BJMBR (2) BABT (1) Autor Ajzen,H. (1) Aragão,E.S. (1) Costa,Paulo Inácio da (1) Donadi,E.A. (1) Ferraz,A.S. (1) Gerbase-DeLima,M. (1) Kimachi,T. (1) Leite,Elza Regina Manzolli (1) Leite,Fábio Renato Manzolli (1) Lima,Oswaldo Luiz Luz (1) Paula-Santos,C.M. (1) Pereira-Santos,A. (1) Sesso,R. (1) Temin,J. (1) Voltarelli,J.C. (1) Mais... Palavra-chave HLA antigens (3) MHC (2) AIDS (1) Alloantibodies (1) Alport's syndrome (1) Focal segmental glomerulosclerosis (1) Genetics (1) HIV (1) Immunogenetics (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2010 (1) 1998 (2) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Frequency of class I anti-HLA alloantibodies in patients infected by HIV-1 BABT Leite,Elza Regina Manzolli; Lima,Oswaldo Luiz Luz; Leite,Fábio Renato Manzolli; Costa,Paulo Inácio da. The aim of this study was to evaluate the presence of class I anti-HLA alloantibodies in patients infected by HIV-1 and relate it with the different clinical courses of the disease. Blood samples were collected in EDTA tubes from 145 individuals. HIV-1 infection was confirmed by ELISA test. The presence of class I anti-HLA alloantibodies and HLA allele's were determined. Clinical evolution was set as fast (<1 year between diagnostic and death), moderate (1-3 years) or slow (>3 years). Class I anti-HLA alloantibodies presence was lower in healthy individuals than in those infected by HIV-1 (4.2% against 32.4%). However, an equal distribution of these alloantibodies was found among the individuals infected, independent on the clinical evolution. Thus,... Tipo: Info:eu-repo/semantics/article Palavras-chave: AIDS; HIV; HLA antigens; Alloantibodies. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000100012 Association of Alport's syndrome with HLA-DR2 antigen in a group of unrelated patients BJMBR Donadi,E.A.; Voltarelli,J.C.; Paula-Santos,C.M.; Kimachi,T.; Ferraz,A.S.. A few family studies have evaluated HLA antigens in Alport's syndrome; however, there are no large population studies. In the present report, we studied 40 unrelated white patients with Alport's syndrome seen at the Unit of Renal Transplantation, Faculty of Medicine of Ribeirão Preto, São Paulo, Brazil. HLA-A, -B, -DR and -DQ antigens were typed using a complement-dependent microlymphocytotoxicity assay. A control white population (N = 403) from the same geographical area was also typed for HLA antigens. Although the frequencies of HLA-A and -B antigens of patients were not statistically different from controls, the frequency of HLA-DR2 antigen observed in patients (65%) was significantly increased in relation to controls (26%; P&lt;0.001). The... Tipo: Info:eu-repo/semantics/article Palavras-chave: HLA antigens; Alport's syndrome; MHC; Immunogenetics. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000400010 Idiopathic focal segmental glomerulosclerosis and HLA antigens BJMBR Gerbase-DeLima,M.; Pereira-Santos,A.; Sesso,R.; Temin,J.; Aragão,E.S.; Ajzen,H.. The objective of the present study was to investigate a possible association between HLA class II antigens and idiopathic focal segmental glomerulosclerosis (FSGS). HLA-A, -B, -DR and -DQ antigens were determined in 19 Brazilian patients (16 white subjects and three subjects of Japanese origin) with biopsy-proven FSGS. Comparison of the HLA antigen frequencies between white patients and white local controls showed a significant increase in HLA-DR4 frequency among FSGS patients (37.7 vs 17.2%, P&lt;0.05). In addition, the three patients of Japanese extraction, not included in the statistical analysis, also presented HLA-DR4. In conclusion, our data confirm the association of FSGS with HLA-DR4 previously reported by others, thus providing further... Tipo: Info:eu-repo/semantics/article Palavras-chave: Focal segmental glomerulosclerosis; Genetics; HLA antigens; MHC. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000300010 Registros recuperados: 3 Primeira ... 1 ... Última

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