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Registros recuperados: 25 | |
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Medel-Flores,Olivia; Valenzuela-Rodríguez,Vania Alejandra; Ocadiz-Delgado,Rodolfo; Castro-Muñoz,Leonardo Josué; Hernández-Leyva,Sandra; Lara-Hernández,Gabriel; Silva-Escobedo,Jesús-Gabriel; Vidal,Patricio Gariglio; Sánchez-Monroy,Virginia. |
Abstract The aim of this study was to evaluate the association between prostate cancer (PCa) and Human papillomavirus (HPV) infection in the Mexican population. We studied 356 paraffin-embedded tissues from unrelated Mexican men with PCa or benign prostatic hyperplasia (BPH), with the latter serving as control. HPV detection was performed by polymerase chain reaction (PCR) using universal primers, and viral genotypes were detected using sequencing or multiplex PCR. Light microscopy analyses enabled the identification of koilocytes in samples subsequently analyzed for HPV detection by in situ PCR and for p16-INK4A expression by immunohistochemistry. The results showed that high risk- (HR) HPVs were detected in 37/189 (19.6%) PCa specimens compared to 16/167... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; Prostate; Cancer; Koilocytes. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000500781 |
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Nobuyoshi Kaneshima,Edilson; Suzuki,Linda Emiko; Taguti Irie,Mary Mayumi; Yoshida,Celina Shizue; Francieli Maia da Silva,Sônia; Lopes Consolaro,Márcia Edilaine. |
Existe atualmente grande preocupação com a melhoria no diagnóstico citopatológico para HPV e para isto tem-se estudado a introdução de critérios morfológicos não-clássicos, tendo em vista a elevada freqüência desta infecção viral bem como o seu potencial carcinogênico. Desta forma, este trabalho objetivou uma releitura de 41 casos positivos para HPV por PCR, cujos critérios inicialmente utilizados foram apenas os clássicos, e introduzir os critérios não clássicos. Os critérios citopatológicos mais observados foram os não clássicos, sendo bi ou multinucleação o mais freqüente, com n=37 (90,24%), seguido de núcleo hipercromático, com n=35 (85,36%) e núcleo em borrão, com n=24 (58,54%). Quanto aos critérios clássicos, a disqueratose foi observada em n=17... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; PCR; Critérios não clássicos. |
Ano: 2005 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572005000100010 |
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Suzuki,Patrícia Sayuri; Oliveira,Karen Brajão de; Herrera,Ana Cristina do Amaral; Borelli,Sueli Donizete; Guembarovski,Roberta Losi; Oliveira,Carlos Eduardo Coral de; Oda,Julie Massayo Maeda; Ozawa,Patricia Midori Murobushi; Watanabe,Maria Angelica Ehara. |
Torque Teno Virus (TTV) presence was investigated in peripheral blood of 117 brazilian women by nested polymerase chain reaction. TTV DNA was observed in 18.6% of healthy donors and in 24.32% Human Papillomavirus (HPV) patients. TTV presence was also investigated in the HPV positive group for comparison between the cervical cancer and noncancerous patients. TTV DNA prevalence was significantly higher among the HPV positive patients with cervical cancer (57.14%) than in HPV noncancerous patients (16.67%). Thus, the presence of TTV infection could be a risk factor for cancer development in the patients presenting HPV-TTV coinfection. Further studies are required to clarify the TTV influence in HPV pathogenesis. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: TTV DNA; HPV; Cervical cancer. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000200010 |
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Silva,Roberto Jose Carvalho da; Sudenga,Staci Lynn; Sichero,Laura; Baggio,Maria Luiza; Galan,Lenice; Cintra,Ricardo; Torres,Benji Nelson; Stoler,Mark; Giuliano,Anna Regina; Villa,Luisa Lina. |
Abstract The aims of this study were to determine the incidence of external genital lesions (EGLs), specifically histologically confirmed condyloma (genital warts) and Penile Intraepithelial Neoplasia (PeIN), and genital HPV infection progression to EGLs among healthy men aged 18-73 residing in Brazil. Subjects included 1118 men enrolled in the HPV Infection in Men (HIM) study between July 2005 and June 2009. At each visit, EGLs were biopsied and subjected to pathological evaluation. HPV status in genital swabs and biopsies was determined by Linear Array and INNO-LiPA, respectively. Age-specific EGLs incidence and the proportion and median time to EGL development were estimated. Kaplan-Meier cumulative incidence rates at 6, 12, and 24 months were... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Men; Genital lesions; PeIN; Condyloma; HPV. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000400376 |
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Giraldo,Paulo C.; Gonçalves,Ana Katherine; Eleutério Junior,José. |
The genital mechanisms of defense are not well understood and are therefore ignored during therapy. This fact results in a great number of cases of treatment failure. The mucosa is an important protective factor of the genital female system, through self-defense mechanisms, and secretor antibodies (immunoglobulin A). The lymphoid tissue exerts protective anti-inflammatory activity, besides inhibiting microorganism adherence, neutralizes viruses and toxins and stabilizes the mucosal flora. Although certain microorganisms, such as viruses and fungus, are controlled by cellular immunity, secretory IgA can also exert an important role in the control of these agents. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vaginal immunity; Genital infections; HPV; Candida albicans; Secretory IgA. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400002 |
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Carvalho,M.O.O; Carestiato,F.N; Perdigão,P.H; Xavier,M.P.P.T; Silva,KC; Botelho,M.O; Oliveira,L.H.S.; Cavalcanti,S.M.B.. |
There is considerable data to support a central role for human papillomavirus (HPV) in the etiology of cervical cancer. More than a 100 HPV types have been described, and 40 have been isolated from benign and malignant genital lesions. Consequently, there is strong motivation to evaluate HPV testing for cervical cancer screening. Few studies concerning the natural history of HPV infection have been conducted in the state of Rio de Janeiro. We determined the prevalence of HPV types in female genital lesions by using Hybrid Capture Assay (HCA) and we retrospectively analyzed the course of HPV infection. Our sample included 788 women attended at Laboratórios Sérgio Franco. The average age of the participants was 29.6 years. HPV prevalence and cytological... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; Cervical cancer; Rio de Janeiro; Brazil. |
Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000500007 |
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Vera-Uehara,Carmina; Sánchez-Alemán,Miguel Angel; Uribe-Salas,Felipe Javier; Ramos-Castañeda,José; Olamendi-Portugal,Ma. Leónidez; Conde-Glez,Carlos Jesús. |
Objectives:To determine the prevalence of HPV and the risky sexual behaviors associated to it in a sample of male college students, taking into account genotype and viral load.Methods:From 2002 to 2003, male students from the Autonomous University of Morelos State completed a questionnaire and provided self-collected genital samples to detect and quantify HPV. We performed a bivariate and a multivariate logistic regression analysis to identify correlates associated with the infection and to assess the viral load as a function of the viral infecting type. The fragments of β-globin gene and L1 of HPV, were amplified, purified and cloned, to evaluate viral load.Results:Among 253 subjects, HPV prevalence was 19.4%, and HPV16 was the most common subtype.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; Viral load; Contraceptive pills; Risky sexual behaviors; Male; Students. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100071 |
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Jalil,Emilia Moreira; Luz,Paula M.; Quintana,Marcel; Friedman,Ruth Khalili; Madeira,Rosa M. Domingues S.; Andrade,Angela Cristina; Chicarino,Janice; Moreira,Ronaldo Ismerio; Derrico,Monica; Levi,José Eduardo; Russomano,Fabio; Veloso,Valdilea Gonçalves; Grinsztejn,Beatriz. |
ABSTRACT Introduction: Cervical cancer remains an important burden for HIV-infected women in the era of combination antiretroviral therapy. Recommendations for cervical screening in these women diverge and may include high-risk HPV (HRHPV) testing. We aimed to evaluate the clinical usefulness of a single HRHPV testing for cervical screening of HIV-infected women. Methods: 723 HIV-infected women from a Brazilian prospective cohort were included between 1996 and 2012. Inclusion criteria were: normal cervical cytology at baseline and having a HRHPV-test at baseline. We calculated incidence rates of any squamous intraepithelial lesion (SIL) and high grade SIL+ (HSIL+) and negative predictive values (NPV) within 12 and 36 months. Hazard Ratios were obtained... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; HIV; Women; Cohort; Incidence. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000100016 |
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Silva,Leila da; Miranda,Angélica; Batalha,Rosieny; Ferreira,Luiz; Santos,Mayara; Talhari,Sinésio. |
ABSTRACT OBJECTIVE: The goal of this study was to determine the prevalence of human papillomavirus infection infection and cervical lesions and its associated factors among HIV infected women attending an AIDS clinic in Amazonas state, Brazil. METHODS: Cross-sectional study. Women attending an AIDS clinic in the city of Manaus between March and December 2011 for gynecological examination were invited to participate. Enrolled patients answered a standardized interview including demographical, behavioral, and clinical data. Additionally, patients underwent a gynecological evaluation with collection of cervical samples for cytological analysis and high-risk human papillomavirus infection hybrid capture. A blood sample was also obtained to determine CD4... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; HIV; Cervical cancer; Brazilian Amazon. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000600557 |
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Carvalho,Maria Odete O.; Almeida,Ricardo W.; Leite,Fátima M. S.; Fellows,Ilza B.; Teixeira,Mariza H.; Oliveira,Ledy H. S.; Cavalcanti,Silvia M. B.. |
Human Papillomavirus (HPV) infection is the main cause of cervical cancers and cervical intraepithelial neoplasias (CIN) worldwide. Consequently, it would be useful to evaluate HPV testing to screen for cervical cancer. Recently developed, the second-generation Hybrid Capture (HCA II) test is a non-radioactive, relatively rapid, liquid hybridization assay designed to detect 18 HPV types, divided into high and low-risk groups. We evaluated 1055 women for HPV infection with the HCA II test. Five hundred and ten (48.3%) of these women had HPV infection; 60 (11.8%) had low cancer-risk HPV DNA; 269 (52.7%) had high-risk HPV types and 181 (35.5%) had both groups. Hence, 450 women (88.2%) in this HPV-infected group had at least one high risk HPV type, and were... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; SIL; Cancer; Hybrid capture. |
Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000200004 |
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Baloch,Zulqarnain; Yasmeen,Nafeesa; Li,Yuanyue; Ma,Ke; Wu,Xiaomei; Yang,Shi-hua; Xia,Xueshan. |
ABSTRACT Background: Dai is a major Chinese ethnic minority group residing in rural areas of the southern part of Yunnan. However, no data exist on the Human Papillomavirus (HPV) prevalence and genotype distribution among Dai women. Method: A total of 793 participants (Dai = 324, Han = 251, other ethnic = 218) were included in this study. PCR was performed to detect the HPV-positive samples, and genotyping was performed with an HPV Geno-Array. Result: The overall HPV prevalence was very low among Dai women compared to the others. The prevalence of high-risk-HPV infections was significantly higher (p = 0.001) among other ethnic women (22.0%) than that among Han (13.1%) and Dai women (7.1%). The overall HPV, high-risk-HPV, single and multiple infection... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; Prevalence; Dai; Genotypes; Rural; Urban; China. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000300325 |
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Gonçalves,Ana Katherine; Cobucci,Ricardo Ney; Rodrigues,Hugo Marcus; Melo,Amanda Gosson de; Giraldo,Paulo César. |
Recently, many studies have evaluated HPV vaccine safety and adverse effects. Two vaccine shave been recently evaluated in randomized controlled trials: the bivalent vaccine for HPV 16 and 18 (Cervarix, GlaxoSmithKline Biologicals, Rixensart, Belgium) and the quadrivalent vaccine for HPV 6, 11, 16, and 18 (Gardasil, Merck and Co., Inc., Whitehouse Station, NJ). We have performed a systematic review of all randomized controlled trials in which HPV vaccines were compared with placebo regarding safety, tolerability and adverse effects. Studies were searched up to March 2013 in the databases: Pubmed, Embase, Scielo and Cancerlit. Odds Ratios (OR) of most incident adverse effects were obtained. Twelve reports, involving 29,540 subjects, were included. In the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; Vaccines; Adverse effects. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600651 |
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Souza,Lúcia Maria de Sena; Miller,William Meihack; Nery,José Augusto da Costa; Andrade,Arnaldo Feitosa Braga de; Asensi,Marise Dutra. |
Despite the prevalence of syphilis worldwide, little is known about its manifestations when associated with other Sexually Transmitted Infections (STI), specifically the Human Papilloma Virus (HPV). Current epidemiological studies show that there is a high incidence of both diseases in ambulatory clinics all over Brazil. This study aims to estimate the incidence of syphilis - HPV co-infections, among patients from the STI ambulatory clinic at the Santa Casa da Misericórdia Hospital, Rio de Janeiro, Brazil. Two-hundred and seven patients were seen in the clinic between March and December 2005, of which 113 (54.6%) sought care for an HPV infection. Blood samples were taken from all patients to check syphilis serology using the flocculation and the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Co-infection; Syphilis; HPV; STD. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000300010 |
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Carestiato,Fernanda N.; Silva,Katia C; Dimetz,Trude; Oliveira,Ledy H. S.; Cavalcanti,Silvia M. B.. |
Human Papillomavirus (HPV) infection is the most prevalent sexually-transmitted virus worldwide. It is known to be the etiological agent of cervical cancer and cervical intraepithelial neoplasia (CIN). Consequently, there is strong motivation to evaluate HPV testing in cervical cancer screening. Recently developed, the second generation of the hybrid capture test (HCA II) is a non-radioactive, relatively rapid, hybridization assay, designed to detect 18 HPV types divided into high and low-risk groups. We evaluated 7,314 patients (5,833 women and 1,481 men) for HPV infection by HCA II. Among them, 3,008 (41.1%) presented HPV infection: 430 (14.2%) had HPV DNA of low risk for cancer, 1,631 (54.2%) had high risk HPV types and 947 (31.5%) had both types. The... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HPV; SIL; Cancer; Hybrid capture. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000500006 |
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Registros recuperados: 25 | |
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