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To study the effect of halothane as a cardioplegic agent, ten Wistar rats were anesthetized by ether inhalation and their hearts were perfused in a Langendorff system with Krebs-Henseleit solution (36oC; 90 cm H2O pressure). After a 15-min period for stabilization the control values for heart rate, force (T), dT/dt and coronary flow were recorded and a halothane-enriched solution (same temperature and pressure) was perfused until cardiac arrest was obtained. The same Krebs-Henseleit solution was reperfused again and the parameters studied were recorded after 1, 3, 5, 10, 20 and 30 min. Cardiac arrest occurred in all hearts during the first two min of perfusion with halothane-bubbled solution. One minute after reperfusion without halothane, the following... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Cardioplegia; Myocardial; Protection; Halothane. |
Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000600009 |
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Natalini,Cláudio Corrêa; Polydoro,Alexandre da Silva. |
Ten healthy adult horses male or female, mean body weight of 424±44.1kg, were anesthetized with romifidine, tiletamine/zolazepam and halothane for 60 minutes using a modified to-and-fro rebreathing anesthetic system, added of 1 liter mechanical dead space. The gas flow rate was 10 liters oxygen/minute during all inhalation anesthetic time. Variables analysed were arterial blood pH, carbon dioxide partial pressure (PaCO2) and oxygen partial pressure (PaO2), and respiratory rate (RR). The horses were allowed to breath spontaneously, and were positioned in right lateral recumbency the arterial O2 values were significantly higher during halothane anesthesia when compared to the baseline values, and significantly lower after induction with tiletamine/zolazepam... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Equine; Horses; Anesthesia; Anaesthesia; Halothane. |
Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84781997000400013 |
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